Research map: Targeted degradation of P-TEFb via MDM2 substrate substitution collapses oncogenic transcriptional programs in MDM2-amplified cancers

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Papers in this map

  1. Driver genomic lesions in MDM2, CDK4, and JUN co-opt targetable super-enhancer networks to impose liposarcomagenic core regulatory circuitry · Ye Chen · 2026 · Cites this paper
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  11. MAP2K6 reprograms NAD+ metabolism via the HMGA1–NAMPT axis to sensitize ovarian cancer cells to PARP inhibition · 2026 · Related

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