MAP2K6 reprograms NAD+ metabolism via the HMGA1–NAMPT axis to sensitize ovarian cancer cells to PARP inhibition

Cell Death and Disease · Published 2026-07-17 · DOI 10.1038/s41419-026-09104-2

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Authors (12)

Ming Wen, Zhuohang Chen, Dongdong Zhan, Mingwei Liu, Shuran Tan, Fang Zhu, Siyu Yang, Jinru Xie, Yu Zhang, Jianjian Li, Lunquan Sun, Rong Tan

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Publication details

Year

2026

Citation

Wen, M., Chen, Z., Zhan, D., et al. (2026). MAP2K6 reprograms NAD+ metabolism via the HMGA1–NAMPT axis to sensitize ovarian cancer cells to PARP inhibition. Cell Death and Disease. https://doi.org/10.1038/s41419-026-09104-2

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