Exploratory Animal and Medical Research · Published 2025-01-01 · DOI 10.52635/eamr/15.1.31-39
The present study was designed to study the role of flaxseed oil in management of rheumatoid arthritis (RA). Chinchadi oil was selected for pain management, which is recommended by Ayurvedic physicians and flaxseed oil is well known for its anti-inflammatory action. Considering this, the objective was to develop omega-3 medicated massage oil and evaluate the efficacy of omega-3 medicated massage oil (prepared using chinchadi oil and flaxseed oil) in the management of Rheumatoid arthritis. This was an open clinical trial which recruited 32 subjects of either sex. The study participants were recruited in two groups. The first group serve as control group received whole body massage with plain chinchadi oil and the experimental group received whole body massage with omega-3 medicated massage oil. The whole-body massage was given for the period of 30 minutes each day for 14 days. Additionally, flaxseed oil softgel capsule (containing 1000 mg omega-3 fatty acid) was given to experimental group for the period of 90 days regularly. At the end of study period, there was significant improvement in grip power of right and left (p<0.05), however in case of walking time, non-significant alteration was observed. Further various other parameters such as morning stiffness, tenderness, swelling and joint pain showed positive alterations. The pathological assessment showed, no gross adverse outcome of massage oil treatment of omega-3 medicated chinchadi oil for two weeks and oral supplementation of flaxseed oil softgel capsule for the period of 90 days. In conclusion, 14-day whole body massage therapy with omega-3 medicated massage oil as topical application and 90 days’ oral supplementation of flaxseed oil in the form of softgel capsules exhibited better clinical improvement over plain chinchadi oil based on pathological and clinical assessment, indicating better efficacy of omega-3 medicated massage oil in the control and management of RA.
Abstract from DOAJ. Public domain (CC0 1.0).
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