Research map: Copper dependency in leukemia metabolism

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  1. Hallmarks of Cancer: New Dimensions · Douglas Hanahan · 2022 · 9836 citations · Cited by this paper
  2. Combined ctDNA and serum PSA for dynamic monitoring of metastatic prostate cancer starting first-line treatment: a prospective national cohort study · 2026 · Related
  3. Copper induces cell death by targeting lipoylated TCA cycle proteins · Peter Tsvetkov · 2022 · 5027 citations · Cited by this paper
  4. GABA signaling activation drives glioblastoma progression in female mice through myeloid-derived suppressor cells · 2026 · Related
  5. Acute Lymphoblastic Leukemia in Children · Stephen P. Hunger · 2015 · 2276 citations · Cited by this paper
  6. PAPOLA-mediated hyperactive polyadenylation promotes leukemogenesis and leukemia stem cell self-renewal through metabolic reprogramming · 2026 · Related
  7. Treating Childhood Acute Lymphoblastic Leukemia without Cranial Irradiation · Ching‐Hon Pui · 2009 · 1236 citations · Cited by this paper
  8. Adjuvant personalized multivalent neoantigen DNA vaccination for MGMT unmethylated glioblastoma: a phase 1 trial · 2026 · Related
  9. Genetic Basis of Acute Lymphoblastic Leukemia · Ilaria Iacobucci · 2017 · 572 citations · Cited by this paper
  10. Tumor irradiation promotes antigen dressing of dendritic cells to enhance CAR T cell persistence and efficacy in lung metastases · 2026 · Related
  11. A druggable copper-signalling pathway that drives inflammation · Stéphanie Solier · 2023 · 337 citations · Cited by this paper
  12. Oncolytic viruses and cytokine-based gene therapies reprogram the tumor microenvironment · 2026 · Related
  13. The Multifaceted Roles of Copper in Cancer: A Trace Metal Element with Dysregulated Metabolism, but Also a Target or a Bullet for Therapy · Pierre Lelièvre · 2020 · 272 citations · Cited by this paper
  14. Targeting PID1 generates oxysterols to switch macrophage cell fates for improved antitumor immunity · 2026 · Related
  15. Mitochondrial metabolism as a potential therapeutic target in myeloid leukaemia · Lucie de Beauchamp · 2021 · 181 citations · Cited by this paper
  16. Bacterial engineering for cancer therapy · 2026 · Related
  17. Coordination of metal center biogenesis in human cytochrome c oxidase · Eva Nývltová · 2022 · 122 citations · Cited by this paper
  18. A high-MAPK, low-WNT cell state drives metastatic dissemination in colorectal cancer · 2026 · Related
  19. Central nervous system involvement in childhood acute lymphoblastic leukemia: challenges and solutions · Maria Thastrup · 2022 · 117 citations · Cited by this paper
  20. Metabolic adaptation of acute lymphoblastic leukemia to the central nervous system microenvironment depends on stearoyl-CoA desaturase · Angela Maria Savino · 2020 · 72 citations · Cited by this paper
  21. Targeting mitochondrial respiration for the treatment of acute myeloid leukemia · Jenna L. Carter · 2020 · 58 citations · Cited by this paper
  22. Inhibition of heme biosynthesis triggers cuproptosis in acute myeloid leukemia · Alexander Charles Lewis · 2025 · 30 citations · Cited by this paper
  23. Targeting mineral metabolism in cancer: Insights into signaling pathways and therapeutic strategies · Kartik Bhatnagar · 2025 · 15 citations · Cited by this paper
  24. Copper depletion boosts CNS leukemia therapy by inhibiting nucleotide synthesis through impairment of mitochondrial complex IV activity · Alan Y. L. Wong · 2026 · 2 citations · Cited by this paper

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