Targeting PID1 generates oxysterols to switch macrophage cell fates for improved antitumor immunity

Nature Cancer · Published 2026-06-16 · DOI 10.1038/s43018-026-01189-0

Authors (25)

Yuxiao Zheng, Qi Wang, Chen Dong, Qiong Wang, Mingshun Han, Haiqing Zhao, Shuang Wang, Longlong Chen, Xiaoli Zhang, Dan Yang, Jun Xiao, Zhihuan Chew, Zhenfei Xie, Lei Yang, Jinyong Fan, Xin Zheng, Dezhen Tu, Weiyun Li, Lingming Zheng, Lijian Hui, Xiaowu Huang, Jinsong Li, Huiru Tang, Bin Wei, Hongyan Wang

Abstract

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Publication details

Year

2026

Citation

Zheng, Y., Wang, Q., Dong, C., et al. (2026). Targeting PID1 generates oxysterols to switch macrophage cell fates for improved antitumor immunity. Nature Cancer. https://doi.org/10.1038/s43018-026-01189-0

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