Annals of Internal Medicine: Clinical Cases · Published 2026-08-01 · DOI 10.7326/aimcc.2025.1292
This report describes a 43-year-old man who presented with muscle cramps and limb pain and was found to have severe hypocalcemia (5.3 mg/dL). Physical examination revealed positive Trousseau and Chvostek signs. Laboratory evaluation showed a low parathyroid hormone level, elevated serum phosphate level, and normal vitamin D level, consistent with primary hypoparathyroidism rather than postoperative causes. Early recognition of these classic neuromuscular signs in an outpatient setting enabled prompt diagnosis and treatment. The patient received intravenous calcium supplementation and was referred for endocrinologic follow-up. This case highlights the clinical value of bedside signs in identifying underlying hypocalcemic disorders.
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Oral, A. (2026). Trousseau and Chvostek Signs in Primary Hypoparathyroidism. Annals of Internal Medicine: Clinical Cases. https://doi.org/10.7326/aimcc.2025.1292