Research map: The Pentose Phosphate Pathway in Immunotherapy

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Papers in this map

  1. mTOR Signaling in Growth, Metabolism, and Disease · Robert A. Saxton · 2017 · 7778 citations · Cited by this paper
  2. Immune landscape of COVID-19 recovery: Nucleocapsid as a major target of CD8+ T cell antiviral responses in convalescent HLA-A*02+ individuals from Brazil · 2026 · Related
  3. T cell exhaustion · E. John Wherry · 2011 · 4141 citations · Cited by this paper
  4. High CD163+CD206+ macrophage infiltration in the bone marrow microenvironment of newly diagnosed multiple myeloma patients · 2026 · Related
  5. A guide to immunometabolism for immunologists · Luke A.J. O'Neill · 2016 · 3332 citations · Cited by this paper
  6. Recombinant human interleukin-32γ facilitates macrophage phagocytosis of Streptococcus pneumoniae by activating nuclear factor kappa B-soluble epoxide hydrolase pathway · 2026 · Related
  7. CAR-T cell therapy: current limitations and potential strategies · Robert C. Sterner · 2021 · 2926 citations · Cited by this paper
  8. Lysosome-induced increase in intracellular granularity of leukocytes: a key morphological biomarker for early sepsis in cell population data · 2026 · Related
  9. Glutathione: Overview of its protective roles, measurement, and biosynthesis · Henry Jay Forman · 2008 · 2646 citations · Cited by this paper
  10. High-dimensional single-cell mass cytometry analysis of IL-4 treated human macrophages reveals heterogeneity and a CD206high anticolitic subset · 2026 · Related
  11. ATP-Citrate Lyase Links Cellular Metabolism to Histone Acetylation · Kathryn E. Wellen · 2009 · 2334 citations · Cited by this paper
  12. SHIP blocks (MDP + LPS)-induced synergy in macrophages independent of catalytic activity · 2026 · Related
  13. The Metabolic Signature of Macrophage Responses · Antonella Viola · 2019 · 2097 citations · Cited by this paper
  14. New Approach Methodologies (NAMs) Complement but Cannot Replace Animal Models in Critical Care Medicine Research · 2026 · Related
  15. Activation of a Metabolic Gene Regulatory Network Downstream of mTOR Complex 1 · Katrin Düvel · 2010 · 2044 citations · Cited by this paper
  16. A role for noncoding RNAs and alternative splicing in the regulation of neutrophil activation and gene expression in systemic lupus erythematosus · 2026 · Related
  17. L-Arginine Modulates T Cell Metabolism and Enhances Survival and Anti-tumor Activity · Roger Geiger · 2016 · 1781 citations · Cited by this paper
  18. Guidelines for single-cell RNA sequencing analysis of eosinophils · 2026 · Related
  19. mTOR regulates memory CD8 T-cell differentiation · Koichi Araki · 2009 · 1591 citations · Cited by this paper
  20. Autofluorescence enables detection and quantification of EETosis in human leukocyte cultures · 2026 · Related
  21. The pentose phosphate pathway and cancer · Krushna Chandra Patra · 2014 · 1471 citations · Cited by this paper
  22. Long-term outcomes following CAR T cell therapy: what we know so far · Kathryn M. Cappell · 2023 · 1414 citations · Cited by this paper
  23. Nrf2 Redirects Glucose and Glutamine into Anabolic Pathways in Metabolic Reprogramming · Yoichiro Mitsuishi · 2012 · 1409 citations · Cited by this paper
  24. Mitochondria Are Required for Antigen-Specific T Cell Activation through Reactive Oxygen Species Signaling · Laura A. Sena · 2013 · 1350 citations · Cited by this paper
  25. Diabetes primes neutrophils to undergo NETosis, which impairs wound healing · Siu Ling Wong · 2015 · 1295 citations · Cited by this paper
  26. An emerging role for neutrophil extracellular traps in noninfectious disease · Selina K. Jorch · 2017 · 1280 citations · Cited by this paper
  27. Metabolic Instruction of Immunity · Michael D. Buck · 2017 · 1245 citations · Cited by this paper
  28. Inhibition of Pyruvate Kinase M2 by Reactive Oxygen Species Contributes to Cellular Antioxidant Responses · Dimitrios Anastasiou · 2011 · 1207 citations · Cited by this paper
  29. Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion · Robert D. Leone · 2019 · 1193 citations · Cited by this paper
  30. The epigenetic landscape of T cell exhaustion · Debattama R. Sen · 2016 · 1018 citations · Cited by this paper
  31. Glucose Metabolism Regulates T Cell Activation, Differentiation, and Functions · Clovis Steve Palmer · 2015 · 1008 citations · Cited by this paper
  32. Mitochondrial stress induced by continuous stimulation under hypoxia rapidly drives T cell exhaustion · Nicole E. Scharping · 2021 · 902 citations · Cited by this paper
  33. Reactive Oxygen Species and Neutrophil Function · Christine C. Winterbourn · 2016 · 896 citations · Cited by this paper
  34. Unraveling the Complex Interplay Between T Cell Metabolism and Function · Ramon I. Klein Geltink · 2018 · 853 citations · Cited by this paper
  35. Metabolic coordination of T cell quiescence and activation · Nicole M. Chapman · 2019 · 781 citations · Cited by this paper
  36. Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation · Valerie A. Gerriets · 2014 · 741 citations · Cited by this paper
  37. The pentose phosphate pathway in health and disease · Tara A. TeSlaa · 2023 · 653 citations · Cited by this paper
  38. Regulation of the pentose phosphate pathway in cancer · Peng Jiang · 2014 · 585 citations · Cited by this paper
  39. T cell stemness and dysfunction in tumors are triggered by a common mechanism · Suman Kumar Vodnala · 2019 · 560 citations · Cited by this paper

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