New Approach Methodologies (NAMs) Complement but Cannot Replace Animal Models in Critical Care Medicine Research

Journal of Leukocyte Biology · Published 2026-08-01 · DOI 10.1093/jleuko/qiag108

Authors (7)

Marlene E Starr, Matthew D Taylor, Longxiang Su, Atsushi Murao, Steve J Schwulst, James A Lederer, Max Brenner

Abstract

PubPorta does not have an abstract for this article yet.

Read the article at the publisher →

Publication details

Year

2026

Citation

Starr, M., Taylor, M., Su, L., et al. (2026). New Approach Methodologies (NAMs) Complement but Cannot Replace Animal Models in Critical Care Medicine Research. Journal of Leukocyte Biology. https://doi.org/10.1093/jleuko/qiag108

Related articles

• Immune landscape of COVID-19 recovery: Nucleocapsid as a major target of CD8+ T cell antiviral responses in convalescent HLA-A*02+ individuals from Brazil · Journal of Leukocyte Biology · 2026 · Same journal
• High CD163+CD206+ macrophage infiltration in the bone marrow microenvironment of newly diagnosed multiple myeloma patients · Journal of Leukocyte Biology · 2026 · Same journal
• Recombinant human interleukin-32γ facilitates macrophage phagocytosis of Streptococcus pneumoniae by activating nuclear factor kappa B-soluble epoxide hydrolase pathway · Journal of Leukocyte Biology · 2026 · Same journal
• Lysosome-induced increase in intracellular granularity of leukocytes: a key morphological biomarker for early sepsis in cell population data · Journal of Leukocyte Biology · 2026 · Same journal
• High-dimensional single-cell mass cytometry analysis of IL-4 treated human macrophages reveals heterogeneity and a CD206high anticolitic subset · Journal of Leukocyte Biology · 2026 · Same journal
• SHIP blocks (MDP + LPS)-induced synergy in macrophages independent of catalytic activity · Journal of Leukocyte Biology · 2026 · Same journal
• A role for noncoding RNAs and alternative splicing in the regulation of neutrophil activation and gene expression in systemic lupus erythematosus · Journal of Leukocyte Biology · 2026 · Same journal
• Guidelines for single-cell RNA sequencing analysis of eosinophils · Journal of Leukocyte Biology · 2026 · Same journal
• Autofluorescence enables detection and quantification of EETosis in human leukocyte cultures · Journal of Leukocyte Biology · 2026 · Same journal
• Sombrero vesicles: from overlooked structures to primary mediators of eosinophil secretion · Journal of Leukocyte Biology · 2026 · Same journal