Research map: Culture-negative periprosthetic joint infection: an umbrella review of prevalence, diagnostic strategies, treatment, and methodological limitations

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Papers in this map

  1. Diagnosis and Management of Prosthetic Joint Infection: Clinical Practice Guidelines by the Infectious Diseases Society of Americaa · Douglas R. Osmon · 2012 · 2301 citations · Cited by this paper
  2. Defining postoperative spinal infections: navigating the inconsistencies in diagnostic definitions · 2025 · Related
  3. The 2018 Definition of Periprosthetic Hip and Knee Infection: An Evidence-Based and Validated Criteria · Javad Parvizi · 2018 · 2169 citations · Cited by this paper
  4. Synovial fluid α -defensin might be false positive in early stages after major total arthroplasty revision surgery · 2026 · Related
  5. Sonication of Removed Hip and Knee Prostheses for Diagnosis of Infection · Andrej Trampuž · 2007 · 1451 citations · Cited by this paper
  6. CarboCell G/C provides sustained high local bone antibiotic levels with minimal systemic exposure, supporting its therapeutic potential in orthopedic infection management · 2026 · Related
  7. The EBJIS definition of periprosthetic joint infection · Martin A. McNally · 2020 · 789 citations · Cited by this paper
  8. Neutrophil extracellular trap (NET)-related index as an indicator of periprosthetic joint infection · 2026 · Related
  9. Diagnosis of Periprosthetic Joint Infection: The Potential of Next-Generation Sequencing · Majd Tarabichi · 2018 · 321 citations · Cited by this paper
  10. Rapid pathogen detection in synovial fluid of acute native joint infections in adults: a clinical evaluation of a novel automated multiplex polymerase chain reaction (mPCR) system · 2025 · Related
  11. Culture-Negative Periprosthetic Joint Infection · Timothy L. Tan · 2018 · 254 citations · Cited by this paper
  12. Treatment of periprosthetic joint infection – outcomes following algorithm-guided treatment at a multidisciplinary referral centre · 2026 · Related
  13. Prior Use of Antimicrobial Therapy is a Risk Factor for Culture-negative Prosthetic Joint Infection · Davud Malekzadeh · 2010 · 226 citations · Cited by this paper
  14. The proportion of chronic periprosthetic joint infection patients with Candida isolates · 2026 · Related
  15. Improved Diagnosis of Prosthetic Joint Infection by Culturing Periprosthetic Tissue Specimens in Blood Culture Bottles · Trisha Nicole Peel · 2016 · 176 citations · Cited by this paper
  16. Effect of novel antimicrobial blue light-emitting optical fiber on vancomycin-resistant Enterococcus faecium and carbapenemase-producing Klebsiella pneumoniae · 2025 · Related
  17. Sonication of Arthroplasty Implants Improves Accuracy of Periprosthetic Joint Infection Cultures · Adam C. Rothenberg · 2017 · 156 citations · Cited by this paper
  18. Osteomyelitis in peri-implant bone of hip prosthetic joint infection: prevalence and clinical impact · 2026 · Related
  19. A Review of the Literature on Culture-Negative Periprosthetic Joint Infection: Epidemiology, Diagnosis and Treatment · Hong-Kwon Yoon · 2017 · 146 citations · Cited by this paper
  20. High intra- and inter-observer reliability of the PJI-TNM classification in acute and chronic periprosthetic hip joint infection · 2026 · Related
  21. Culture-negative periprosthetic joint infection: prevalence, aetiology, evaluation, recommendations, and treatment · Irene L. Kalbian · 2020 · 124 citations · Cited by this paper
  22. Optimal Periprosthetic Tissue Specimen Number for Diagnosis of Prosthetic Joint Infection · Trisha Nicole Peel · 2016 · 117 citations · Cited by this paper
  23. Next generation sequencing for pathogen detection in periprosthetic joint infections · Pier Francesco Indelli · 2021 · 89 citations · Cited by this paper
  24. Debridement, antibiotics, and implant retention (DAIR) for the early prosthetic joint infection of total knee and hip arthroplasties: a systematic review · Umile Giuseppe Longo · 2023 · 82 citations · Cited by this paper
  25. The Effect of Preoperative Antimicrobial Prophylaxis on Intraoperative Culture Results in Patients with a Suspected or Confirmed Prosthetic Joint Infection: a Systematic Review · Marjan Wouthuyzen‐Bakker · 2017 · 77 citations · Cited by this paper
  26. Next-Generation Sequencing Supports Targeted Antibiotic Treatment for Culture Negative Orthopedic Infections · Ravina Kullar · 2022 · 77 citations · Cited by this paper
  27. An Enhanced Understanding of Culture-Negative Periprosthetic Joint Infection with Next-Generation Sequencing: A Multicenter Study. · Karan Goswami · 2022 · 69 citations · Cited by this paper
  28. The Effectiveness of Metagenomic Next-Generation Sequencing in the Diagnosis of Prosthetic Joint Infection: A Systematic Review and Meta-Analysis · Jun Tan · 2022 · 66 citations · Cited by this paper
  29. Do Culture-Negative Periprosthetic Joint Infections Have a Worse Outcome Than Culture-Positive Periprosthetic Joint Infections? A Systematic Review and Meta-Analysis · Marie–Jacqueline Reisener · 2018 · 51 citations · Cited by this paper
  30. Diagnostic Value of Next‐Generation Sequencing in Periprosthetic Joint Infection: A Systematic Review · Yuchen Tang · 2021 · 38 citations · Cited by this paper
  31. Performance of Sequencing Assays in Diagnosis of Prosthetic Joint Infection: A Systematic Review and Meta-Analysis · Mingyang Li · 2019 · 35 citations · Cited by this paper
  32. First evaluation of a commercial multiplex PCR panel for rapid detection of pathogens associated with acute joint infections · Jorrit W. A. Schoenmakers · 2023 · 34 citations · Cited by this paper
  33. Diagnostic accuracy of 16S rDNA PCR, multiplex PCR and metagenomic next-generation sequencing in periprosthetic joint infections: a systematic review and meta-analysis · Flaminia Olearo · 2025 · 29 citations · Cited by this paper
  34. Debridement, Antibiotic Pearls, and Retention of the Implant (DAPRI) in the Treatment of Early Periprosthetic Joint Infections: A Consecutive Series · Pier Francesco Indelli · 2023 · 22 citations · Cited by this paper
  35. Comparable clinical outcomes of culture-negative and culture-positive periprosthetic joint infections: a systematic review and meta-analysis · Feng Li · 2023 · 20 citations · Cited by this paper
  36. Outcomes of culture-negative or -positive periprosthetic joint infections: A systematic review and meta-analysis · Yahao Lai · 2023 · 16 citations · Cited by this paper
  37. Higher diagnostic value of next‐generation sequencing versus culture in periprosthetic joint infection: A systematic review and meta‐analysis · Shilong Su · 2024 · 14 citations · Cited by this paper
  38. Multiplex PCR in septic arthritis and periprosthetic joint infections microorganism identification: Results from the application of a new molecular testing diagnostic algorithm · Stefano Ghirardelli · 2024 · 12 citations · Cited by this paper
  39. 2025 ICM: One-Stage Exchange · Erik Nathan Hansen · 2025 · 6 citations · Cited by this paper

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