Research map: Epigenetic legacies of famine: mechanistic pathways to obesity in modern environments

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  1. Targeting non-coding RNAs to overcome cancer therapy resistance · Baoqing Chen · 2022 · 448 citations · Cited by this paper
  2. Lipid-based nanocarrier-enabled combination therapy for breast cancer: overcoming drug resistance toward precision oncology · 2026 · Related
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  5. An Overview of Epigenetics in Obesity: The Role of Lifestyle and Therapeutic Interventions · Abeer Mostafa Mahmoud · 2022 · 186 citations · Cited by this paper
  6. EPA-loaded silica nanoemulsions attenuate DEN-induced hepatic fibroinflammation by modulating homocysteine, PKCα/NF-κB, and Nrf2 signaling · 2026 · Related
  7. Hypothalamus-pituitary-adrenal and gut-brain axes in biological interaction pathway of the depression · Amanda Gollo Bertollo · 2025 · 140 citations · Cited by this paper
  8. Cycloastragenol overcomes trastuzumab resistance in HER2-positive breast cancer by regulating cell cycle and epithelial-mesenchymal transition through EZH2/PTEN/AKT pathway · 2026 · Related
  9. New Insights into the Role of Insulin and Hypothalamic-Pituitary-Adrenal (HPA) Axis in the Metabolic Syndrome · J. A. M. J. L. Janssen · 2022 · 132 citations · Cited by this paper
  10. Exploring betanin regulatory impact on TGF-β and PI3K/AKT pathways in oral cancer · 2026 · Related
  11. Dietary nutrients shape gut microbes and intestinal mucosa via epigenetic modifications · Jianmin Wu · 2020 · 131 citations · Cited by this paper
  12. Myrtenol modulates TWEAK/TLR4–NF-κB, miR-21, PTEN, and ERK-1 expressions and improves behavioral outcomes in a rat glioblastoma model · 2026 · Related
  13. Epigenetic regulation of transcription factors involved in NLRP3 inflammasome and NF-kB signaling pathways · John Kaszycki · 2025 · 78 citations · Cited by this paper
  14. Protective effects of ginseng against reproductive injury: mechanisms and research progress · 2026 · Related
  15. Exploring the Connection Between BDNF/TrkB and AC/cAMP/PKA/CREB Signaling Pathways: Potential for Neuroprotection and Therapeutic Targets for Neurological Disorders · Abhishek Kumar Gupta · 2025 · 53 citations · Cited by this paper
  16. Development of citrinin-loaded liposomes and in vitro toxicogenetic evaluation on breast cells · 2026 · Related
  17. The cortisol axis and psychiatric disorders: an updated review · Mina Y. George · 2025 · 53 citations · Cited by this paper
  18. Decoding the Adipocyte Epigenome: Differentiation, Metabolic Memory, and Obesity · 2025 · Related
  19. Genetic basis of early onset and progression of type 2 diabetes in South Asians · Sam Hodgson · 2024 · 45 citations · Cited by this paper
  20. Inflammatory and Immune Biomarkers in Mood Disorders: From Mechanistic Pathways to Clinical Translation · Mario Pinzi · 2025 · 38 citations · Cited by this paper
  21. Windows of Vulnerability: Consequences of Exposure Timing during the Dutch Hunger Winter · Daniel Ramirez · 2022 · 31 citations · Cited by this paper
  22. Adaptive Effects of Endocrine Hormones on Metabolism of Macronutrients during Fasting and Starvation: A Scoping Review · Reza M. Karimi · 2024 · 31 citations · Cited by this paper
  23. Survival of the fattest: How body fat and migration influence survival in highly seasonal environments · Kristin Denryter · 2022 · 29 citations · Cited by this paper
  24. Epigenetic regulation of autophagy by histone-modifying enzymes under nutrient stress · Young Suk Yu · 2023 · 28 citations · Cited by this paper
  25. Metabolic imbalance driving immune cell phenotype switching in autoimmune disorders: Tipping the balance of T‐ and B‐cell interactions · Matteo Barberis · 2024 · 28 citations · Cited by this paper
  26. Metabolic Disturbances Involved in Cardiovascular Diseases: The Role of Mitochondrial Dysfunction, Altered Bioenergetics and Oxidative Stress · Donatella Pietrangelo · 2025 · 25 citations · Cited by this paper
  27. The association between prenatal famine, DNA methylation and mental disorders: a systematic review and meta-analysis · Heike Eichenauer · 2023 · 22 citations · Cited by this paper
  28. Nutrition, Gut Microbiota, and Epigenetics in the Modulation of Immune Response and Metabolic Health · Sabrin Bacaloni · 2025 · 19 citations · Cited by this paper
  29. Natural selection and human adiposity: crafty genotype, thrifty phenotype · Jonathan C. K. Wells · 2023 · 17 citations · Cited by this paper
  30. miRNA and leptin signaling in metabolic diseases and at extreme environments · Samrita Mondal · 2024 · 17 citations · Cited by this paper
  31. Obesity and nutritional strategies: advancing prevention and management through evidence-based approaches · Rosario Suárez · 2025 · 17 citations · Cited by this paper
  32. Association between Early Life Famine Exposure and Metabolic Syndrome in Adulthood · Fan Yao · 2022 · 16 citations · Cited by this paper
  33. Recent Evidences of Epigenetic Alterations in Chronic Obstructive Pulmonary Disease (COPD): A Systematic Review · Rosetta Ragusa · 2025 · 14 citations · Cited by this paper
  34. Mitochondrial dysfunction and epigenetics underlying the link between early-life nutrition and non-alcoholic fatty liver disease · Anabela La Colla · 2022 · 13 citations · Cited by this paper
  35. Adaptive Responses in Severe Acute Malnutrition: Endocrinology, Metabolomics, Mortality, and Growth · LAURA C. PAGE · 2025 · 12 citations · Cited by this paper
  36. Epigenetic Mechanisms and Nephrotic Syndrome: A Systematic Review · Samantha Hayward · 2023 · 11 citations · Cited by this paper
  37. Potential of Modulating Aldosterone Signaling and Mineralocorticoid Receptor with microRNAs to Attenuate Diabetic Kidney Disease · Shinji Hagiwara · 2024 · 11 citations · Cited by this paper
  38. Lipotoxicity in a Vicious Cycle of Pancreatic Beta Cell Exhaustion · Vladimir Grubelnik · 2022 · 10 citations · Cited by this paper
  39. Slim choices: young people’s experiences of individual responsibility for childhood obesity · Zofia Boni · 2020 · 9 citations · Cited by this paper

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