Research map: The potential role of trained immunity in HIV-associated atherosclerotic cardiovascular disease: mechanisms and therapeutic implications

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  1. A guide to immunometabolism for immunologists · Luke A.J. O'Neill · 2016 · 3332 citations · Cited by this paper
  2. A review of soluble mediator and cytokine networks linking combination immunotherapy, tumor microenvironment remodeling and skeletal muscle dysfunction · 2026 · Related
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  4. GFI1 as a novel regulator of γδ T cell development and the IL-17/IFN-γ lineage commitment · 2026 · Related
  5. mTOR- and HIF-1α–mediated aerobic glycolysis as metabolic basis for trained immunity · Shih‐Chin Cheng · 2014 · 2272 citations · Cited by this paper
  6. HIF-1α-centered metabolic reprogramming in osteoarthritis: cell type-specific effects and intercellular crosstalk among chondrocytes, BMSCs, and macrophages · 2026 · Related
  7. Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity · Sadia Saeed · 2014 · 1805 citations · Cited by this paper
  8. Acquired immune-mediated thrombotic thrombocytopenic purpura with severe cholestatic liver injury and reversible acute kidney injury after ivonescimab-containing chemoimmunotherapy: a case report and literature review · 2026 · Related
  9. Trained Immunity: A Memory for Innate Host Defense · Mihai Gheorghe Netea · 2011 · 1712 citations · Cited by this paper
  10. Lipoprotein (a) fuels EV71 replication by activating p38 MAPK-autophagy axis · 2026 · Related
  11. Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity · Rob J.W. Arts · 2016 · 911 citations · Cited by this paper
  12. The role of trained immunity in chronic non-communicable inflammatory diseases · 2025 · Related
  13. Metabolic Induction of Trained Immunity through the Mevalonate Pathway · Siroon Bekkering · 2018 · 790 citations · Cited by this paper
  14. Persistent IFN-I signaling inhibits mitochondrial oxidative metabolism in CD8+ T cells during HIV-1 infection under cART · 2026 · Related
  15. Immunometabolic Pathways in BCG-Induced Trained Immunity · Rob J.W. Arts · 2016 · 695 citations · Cited by this paper
  16. Trained Immunity and Cardiovascular Risk: An Immunological Perspective · 2026 · Related
  17. Trained immunity, tolerance, priming and differentiation: distinct immunological processes · Maziar Divangahi · 2020 · 627 citations · Cited by this paper
  18. Trained immunity in monocytes and macrophages in atherosclerotic cardiovascular disease · 2026 · Related
  19. Pitavastatin to Prevent Cardiovascular Disease in HIV Infection · Steven Kyle Grinspoon · 2023 · 498 citations · Cited by this paper
  20. A statin-loaded reconstituted high-density lipoprotein nanoparticle inhibits atherosclerotic plaque inflammation · Raphaël Duivenvoorden · 2014 · 445 citations · Cited by this paper
  21. HIV infection and cardiovascular disease · Lars G. Hemkens · 2014 · 249 citations · Cited by this paper
  22. Cardiovascular Disease and HIV Infection · Virginia A. Triant · 2013 · 244 citations · Cited by this paper
  23. Inhibiting macrophage proliferation suppresses atherosclerotic plaque inflammation · Jun Tang · 2015 · 233 citations · Cited by this paper
  24. HIV infection and coronary heart disease: mechanisms and management · Priscilla Y. Hsue · 2019 · 233 citations · Cited by this paper
  25. Trained immunity: adaptation within innate immune mechanisms · Jorge Domínguez‐Andrés · 2022 · 203 citations · Cited by this paper
  26. Cytokine Circuits in Cardiovascular Disease · Jesse W. Williams · 2019 · 175 citations · Cited by this paper
  27. Immunometabolic control of trained immunity · Niels P. Riksen · 2020 · 173 citations · Cited by this paper
  28. BCG-induced trained immunity: history, mechanisms and potential applications · Jingjing Chen · 2023 · 168 citations · Cited by this paper
  29. Aorta- and liver-generated TMAO enhances trained immunity for increased inflammation via ER stress/mitochondrial ROS/glycolysis pathways · Fatma Saaoud · 2022 · 148 citations · Cited by this paper
  30. HIV Proteins and Endothelial Dysfunction: Implications in Cardiovascular Disease · Appakkudal R. Anand · 2018 · 146 citations · Cited by this paper
  31. Trained immunity: General and emerging concepts · Patricia Vuscan · 2024 · 138 citations · Cited by this paper
  32. Rewiring of glucose metabolism defines trained immunity induced by oxidized low-density lipoprotein · Samuel T. Keating · 2020 · 133 citations · Cited by this paper
  33. Projections of non-communicable disease and health care costs among HIV-positive persons in Italy and the U.S.A.: A modelling study · Mikaëla Smit · 2017 · 132 citations · Cited by this paper
  34. Inflammation in HIV and Its Impact on Atherosclerotic Cardiovascular Disease · Laventa M. Obare · 2024 · 121 citations · Cited by this paper
  35. Myocardial infarction drives trained immunity of monocytes, accelerating atherosclerosis · Zheng N. Dong · 2023 · 120 citations · Cited by this paper
  36. Trained Immunity and Reactivity of Macrophages and Endothelial Cells · Charles Drummer · 2020 · 118 citations · Cited by this paper
  37. The role of neutrophils in trained immunity · Lydia Kalafati · 2022 · 110 citations · Cited by this paper
  38. Microbial translocation is a cause of systemic immune activation in chronic HIV infection · Jason M. Brenchley · 2006 · 103 citations · Cited by this paper
  39. Aldosterone induces trained immunity: the role of fatty acid synthesis · Charlotte D.C.C. van der Heijden · 2019 · 101 citations · Cited by this paper

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