Research map: Bone- and muscle-targeted adeno-associated viral vectors enable tissue-selective vitamin D receptor knockdown in mice

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  1. A robust and high-throughput Cre reporting and characterization system for the whole mouse brain · Linda Madisen · 2009 · 7610 citations · Cited by this paper
  2. Type 2 Diabetes and Falls Incidents among the Elderly: An Umbrella Review of their Associations with Vitamin D Levels and Other Salient Peer Reviewed Research Observations · Ray Marks · 2026 · Cites this paper
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  6. Mice lacking the vitamin D receptor exhibit impaired bone formation, uterine hypoplasia and growth retardation after weaning · Tatsuya Yoshizawa · 1997 · 1184 citations · Cited by this paper
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  8. Targeted ablation of the vitamin D receptor: An animal model of vitamin D-dependent rickets type II with alopecia · Yan Chun Li · 1997 · 960 citations · Cited by this paper
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  10. Duodenal calcium absorption in vitamin D receptor–knockout mice: Functional and molecular aspects · Sophie J. Van Cromphaut · 2001 · 596 citations · Cited by this paper
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  12. The AAV Vector Toolkit: Poised at the Clinical Crossroads · Aravind Asokan · 2012 · 472 citations · Cited by this paper
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  14. Deletion of Vitamin D Receptor Gene in Mice Results in Abnormal Skeletal Muscle Development with Deregulated Expression of Myoregulatory Transcription Factors · Itsuro Endo · 2003 · 433 citations · Cited by this paper
  15. rAAV8 encapsidated HMR-001/z enables high efficiency hepatic transduction and restores hemostasis in hemophilic mice · 2026 · Related
  16. Identification of a myotropic AAV by massively parallel in vivo evaluation of barcoded capsid variants · Jonas Weinmann · 2020 · 271 citations · Cited by this paper
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  18. Design of Tissue-specific Regulatory Cassettes for High-level rAAV-mediated Expression in Skeletal and Cardiac Muscle · Maja Z. Salva · 2007 · 233 citations · Cited by this paper
  19. Assessment of F/HN-pseudotyped lentiviral vector following intravenous delivery to mice · 2026 · Related
  20. Gene targeting restricted to mouse striated muscle lineage · Pierre Miniou · 1999 · 231 citations · Cited by this paper
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  22. Inducible Cre transgenic mouse strain for skeletal muscle-specific gene targeting · John Joseph McCarthy · 2012 · 210 citations · Cited by this paper
  23. Optimization of AAV expression cassettes to improve packaging capacity and transgene expression in neurons · Jun-Hyeok Choi · 2014 · 196 citations · Cited by this paper
  24. Gene Regulation by Vitamin D3 · Carsten Carlberg · 1998 · 193 citations · Cited by this paper
  25. Vitamin D Receptor in Osteoblasts Is a Negative Regulator of Bone Mass Control · Yoko Yamamoto · 2013 · 179 citations · Cited by this paper
  26. Systemic AAV-9 transduction in mice is influenced by animal age but not by the route of administration · Benjamin Carlos Bostick · 2007 · 177 citations · Cited by this paper
  27. A Single Intravenous Injection of Adeno-associated Virus Serotype-9 Leads to Whole Body Skeletal Muscle Transduction in Dogs · Yongping Yue · 2008 · 173 citations · Cited by this paper
  28. Liver-specific microRNA-122 target sequences incorporated in AAV vectors efficiently inhibits transgene expression in the liver · C Qiao · 2010 · 164 citations · Cited by this paper
  29. Improved cardiac gene transfer by transcriptional and transductional targeting of adeno-associated viral vectors · Oliver Josef Müller · 2006 · 158 citations · Cited by this paper
  30. Vitamin D Receptor Ablation and Vitamin D Deficiency Result in Reduced Grip Strength, Altered Muscle Fibers, and Increased Myostatin in Mice · Christian M. Girgis · 2015 · 155 citations · Cited by this paper
  31. Construction and analysis of compact muscle-specific promoters for AAV vectors · Bowen Wang · 2008 · 149 citations · Cited by this paper
  32. Adeno-associated virus vector-mediated gene transfer into dystrophin-deficient skeletal muscles evokes enhanced immune response against the transgene product · Katsutoshi Yuasa · 2002 · 136 citations · Cited by this paper
  33. Mice with myocyte deletion of vitamin D receptor have sarcopenia and impaired muscle function · Christian M. Girgis · 2019 · 134 citations · Cited by this paper
  34. The Vitamin D/Vitamin D receptor (VDR) axis in muscle atrophy and sarcopenia · Shelby E. Bollen · 2022 · 117 citations · Cited by this paper
  35. Deletion of the vitamin D receptor specifically in the parathyroid demonstrates a limited role for the receptor in parathyroid physiology · Tomer Meir · 2009 · 81 citations · Cited by this paper
  36. Vitamin D and Its Receptor from a Structural Perspective · Natacha Rochel · 2022 · 78 citations · Cited by this paper
  37. MyoD-cre transgenic mice: A model for conditional mutagenesis and lineage tracing of skeletal muscle · Jennifer C. J. Chen · 2005 · 68 citations · Cited by this paper
  38. Next-generation muscle-directed gene therapy by in silico vector design · Shilpita Sarcar · 2019 · 60 citations · Cited by this paper
  39. In Vivo Gene Editing of Muscle Stem Cells with Adeno-Associated Viral Vectors in a Mouse Model of Duchenne Muscular Dystrophy · Jennifer B. Kwon · 2020 · 60 citations · Cited by this paper

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