Research map: Gingival mesenchymal stem cell-derived exosomes ameliorate human adult keratinocyte transformed cell line inflammation and apoptosis via the TLR4/NF-κB pathway

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  1. Mesenchymal Stem Cells Derived from Human Gingiva Are Capable of Immunomodulatory Functions and Ameliorate Inflammation-Related Tissue Destruction in Experimental Colitis · Qunzhou Zhang · 2009 · 765 citations · Cited by this paper
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  4. Azoxystrobin induces mitochondrial apoptosis by inhibiting cytochrome b Qo site of mitochondrial complex Ⅲ in oral leukoplakia cells and a mouse model · 2026 · Related
  5. Exosomes from TNF-α-treated human gingiva-derived MSCs enhance M2 macrophage polarization and inhibit periodontal bone loss · Yuki Nakao · 2020 · 467 citations · Cited by this paper
  6. DDX24 exacerbates inflammation-induced immunosuppression in oral squamous cell carcinoma progression through IL-17 signaling pathway · 2026 · Related
  7. Exosomes derived from human adipose tissue-derived mesenchymal stem cells alleviate atopic dermatitis · Byong Seung Cho · 2018 · 320 citations · Cited by this paper
  8. “Clinical efficacy and expression of antimicrobial resistance genes after using a novel herbal mouthwash compared to chlorhexidine: A Randomised controlled trial in generalised gingivitis patients” · 2026 · Related
  9. Immune mechanisms in oral lichen planus · Asma El‐Howati · 2022 · 221 citations · Cited by this paper
  10. Periodontal pathogen–driven endotoxemia and bacteremia as a mechanistic link to liver disease. A scoping review · 2026 · Related
  11. TNF-α stimulation enhances the neuroprotective effects of gingival MSCs derived exosomes in retinal ischemia-reperfusion injury via the MEG3/miR-21a-5p axis · Ziyu Yu · 2022 · 169 citations · Cited by this paper
  12. Vertical facial discrepancies in Brazilian children and adolescents are associated with polymorphisms in members of the Wnt gene family · 2026 · Related
  13. Exosomes released from educated mesenchymal stem cells accelerate cutaneous wound healing via promoting angiogenesis · Xinyu Qiu · 2020 · 161 citations · Cited by this paper
  14. mRNA and lncRNA expression profiles as potential targets for diagnosis and treatment of oral lichen planus · 2026 · Related
  15. Oral lichen planus: comparative efficacy and treatment costs—a systematic review · Shaiba Sandhu · 2022 · 76 citations · Cited by this paper
  16. Regulatory roles of gingival fibroblasts in periodontal homeostasis and inflammatory progression · 2026 · Related
  17. Topical calcineurin inhibitors in the treatment of oral lichen planus: a systematic review and meta‐analysis · Silu Sun · 2019 · 69 citations · Cited by this paper
  18. The role of FAT family cadherins in craniofacial development: A scoping review · 2026 · Related
  19. MSCs‑derived exosomes attenuate ischemia-reperfusion brain injury and inhibit microglia apoptosis might via exosomal miR-26a-5p mediated suppression of CDK6 · Chang Cheng · 2021 · 68 citations · Cited by this paper
  20. The influence of food hardness on the physiological parameters of mastication in children: A scoping review · 2026 · Related
  21. Autoimmune disorders in oral lichen planus: A systematic review and meta‐analysis · Teresa De Porras‐Carrique · 2022 · 68 citations · Cited by this paper
  22. Gingival mesenchymal stem cell‐derived exosomes are immunosuppressive in preventing collagen‐induced arthritis · Xiaohong Tian · 2021 · 67 citations · Cited by this paper
  23. Enhancing bone regeneration and immunomodulation via gelatin methacryloyl hydrogel-encapsulated exosomes from osteogenic pre-differentiated mesenchymal stem cells · Xiaorong Li · 2024 · 66 citations · Cited by this paper
  24. The molecular mechanisms of the effect of Dexamethasone and Cyclosporin A on TLR4 /NF-κB signaling pathway activation in oral lichen planus · Yana Ge · 2012 · 62 citations · Cited by this paper
  25. Human gingival mesenchymal stem cell‐derived exosomes cross‐regulate the Wnt/β‐catenin and NF‐κB signalling pathways in the periodontal inflammation microenvironment · Yingzhe Hu · 2023 · 59 citations · Cited by this paper
  26. Vitamin D/VDR signaling suppresses microRNA‐802‐induced apoptosis of keratinocytes in oral lichen planus · Bin Zhao · 2018 · 54 citations · Cited by this paper
  27. Oral Lichen Planus: An Updated Review of Etiopathogenesis, Clinical Presentation, and Management · Yashpal Manchanda · 2023 · 52 citations · Cited by this paper
  28. Exosomes Derived From Human Gingival Mesenchymal Stem Cells Attenuate the Inflammatory Response in Periodontal Ligament Stem Cells · Jiayao Sun · 2022 · 51 citations · Cited by this paper
  29. TLR4 and TLR9 are induced in oral lichen planus · Maria Siponen · 2012 · 38 citations · Cited by this paper
  30. Study on the Role of Salivary Flora and NF-κB Inflammatory Signal Pathway in Oral Lichen Planus · Songsong Deng · 2020 · 28 citations · Cited by this paper
  31. Alteration of Streptococcus salivarius in Buccal Mucosa of Oral Lichen Planus and Controlled Clinical Trial in OLP Treatment · Yuting Li · 2020 · 28 citations · Cited by this paper
  32. Escherichia coli enhances Th17/Treg imbalance via TLR4/NF-κB signaling pathway in oral lichen planus · Jia Wang · 2023 · 28 citations · Cited by this paper
  33. S100A9 Exacerbates the Inflammation in Rosacea through Toll-Like Receptor 4/MyD88/NF-κB Signaling Pathway · Yan Le · 2024 · 23 citations · Cited by this paper
  34. Exosomes Derived From Human Gingival Mesenchymal Stem Cells Induce Metabolic Reprogramming of Inflammatory Macrophages · Jialu Wang · 2025 · 21 citations · Cited by this paper
  35. Downregulation of toll‐like receptor‐mediated signalling pathways in oral lichen planus · Suraya Hani Mohd Sinon · 2015 · 20 citations · Cited by this paper
  36. In vitro cell culture system optimization of keratinocytes from oral lichen planus ( OLP ) patients · Tianyu Cao · 2016 · 19 citations · Cited by this paper
  37. Probiotics as Potential Biological Immunomodulators in the Management of Oral Lichen Planus: What’s New? · Paola Zanetta · 2022 · 18 citations · Cited by this paper
  38. Altered Expression of Toll-like Receptors in Human Oral Epithelium in Oral Lichenoid Reactions · Abdelhakim Salem · 2016 · 17 citations · Cited by this paper
  39. Gingival-derived mesenchymal stem cells alleviate allergic asthma inflammation via HGF in animal models · Qiannan Fang · 2024 · 11 citations · Cited by this paper

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