Research map: Importance of Inclusion of Representative Populations in Pivotal Clinical Trials: Zolbetuximab as an Example

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Papers in this map

  1. First-line nivolumab plus chemotherapy versus chemotherapy alone for advanced gastric, gastro-oesophageal junction, and oesophageal adenocarcinoma (CheckMate 649): a randomised, open-label, phase 3 trial · Yelena Yuriy Janjigian · 2021 · 3119 citations · Cited by this paper
  2. Statistical and Methodological Considerations in the Evaluation of Ultra-Low-Dose Nivolumab · 2026 · Related
  3. Zolbetuximab plus mFOLFOX6 in patients with CLDN18.2-positive, HER2-negative, untreated, locally advanced unresectable or metastatic gastric or gastro-oesophageal junction adenocarcinoma (SPOTLIGHT): a multicentre, randomised, double-blind, phase 3 trial · Kohei Shitara · 2023 · 826 citations · Cited by this paper
  4. Virtual Sustained Tobacco Treatment for Patients With Cancer: A Randomized Controlled Trial (ECOG-ACRIN: EAQ171CD) Within the National Cancer Institute Community Oncology Research Program · 2026 · Related
  5. Zolbetuximab plus CAPOX in CLDN18.2-positive gastric or gastroesophageal junction adenocarcinoma: the randomized, phase 3 GLOW trial · Manish A. Shah · 2023 · 657 citations · Cited by this paper
  6. Innovate or Be Left Behind: A Path to Prospective External Control Arms for Accelerated Oncology Drug Development · 2026 · Related
  7. Epidemiology of stomach cancer · Milena Ilić · 2022 · 508 citations · Cited by this paper
  8. AAML1831: A Phase III Trial Comparing Standard Induction Therapy With CPX-351 in De Novo Pediatric AML: A Report From the Children's Oncology Group · 2026 · Related
  9. Characteristics of gastric cancer around the world · María José López · 2022 · 436 citations · Cited by this paper
  10. Clinical and Psychological Outcomes After Monoclonal Gammopathy Screening: A Population-Based Screening Study and Subsequent Randomized Trial of Follow-Up · 2026 · Related
  11. Racial/ethnic differences in drug disposition and response: Review of recently approved drugs · Anuradha Ramamoorthy · 2015 · 351 citations · Cited by this paper
  12. Phase I/II Study of Sonrotoclax (BGB-11417) Monotherapy in Patients With Mantle Cell Lymphoma Previously Treated With Anti-CD20 Therapy and a Bruton Tyrosine Kinase Inhibitor · 2026 · Related
  13. The Clinical Evidence Linking Helicobacter pylori to Gastric Cancer · Steven F. Moss · 2016 · 326 citations · Cited by this paper
  14. SKYSCRAPER-01: Tiragolumab in Combination With Atezolizumab in Previously Untreated PD-L1–High, Locally Advanced, Unresectable or Metastatic Non–Small Cell Lung Cancer · 2026 · Related
  15. Signatures of tumour immunity distinguish Asian and non-Asian gastric adenocarcinomas · Suling J. Lin · 2014 · 236 citations · Cited by this paper
  16. Moderate Hypofractionation for Regional Node Irradiation Is Safe and Effective · 2026 · Related
  17. Comparisons of Gastric Cancer Treatments: East vs. West · Kai A. Bickenbach · 2012 · 159 citations · Cited by this paper
  18. Beyond Statistical Significance: Methodological Fragility and Censoring Bias in the 5-Year Update of CheckMate 743 · 2026 · Related
  19. Comparison of Gastric Cancer Survival Between Caucasian and Asian Patients Treated in the United States: Results from the Surveillance Epidemiology and End Results (SEER) Database · Jiping Wang · 2015 · 110 citations · Cited by this paper
  20. Limiting Dexamethasone Exposure With Highly Emetogenic Chemotherapy Regimens: Is the Verdict In? · 2026 · Related
  21. The difference in gastric cancer between Japan, USA and Europe: What are the facts? What are the suggestions? · Peter A. Davis · 2001 · 108 citations · Cited by this paper
  22. BiDil for Heart Failure in Black Patients: The U.S. Food and Drug Administration Perspective · Robert Temple · 2007 · 108 citations · Cited by this paper
  23. Epidemiological Review of Gastroesophageal Junction Adenocarcinoma in Asian Countries · Noriaki Manabe · 2021 · 74 citations · Cited by this paper
  24. Discordance of Somatic Mutations Between Asian and Caucasian Patient Populations with Gastric Cancer · Feifei Jia · 2016 · 39 citations · Cited by this paper
  25. Regulatory and Scientific Issues Regarding Use of Foreign Data in Support of New Drug Applications in the United States: An FDA Perspective · Ni A. Khin · 2013 · 38 citations · Cited by this paper
  26. Importing oncology trials from China: a bridge over troubled waters? · Harpreet Singh · 2022 · 24 citations · Cited by this paper
  27. Non-CpG sites preference in G:C > A:T transition of TP53 in gastric cancer of Eastern Europe (Poland, Romania and Hungary) compared to East Asian countries (China and Japan) · Hiroko Natsume · 2023 · 18 citations · Cited by this paper
  28. Helicobacter pylori Across Continents: Contrasts in Epidemiology, Genetics, Clinical Impact, and Management Between East and West · Ken Namikawa · 2025 · 14 citations · Cited by this paper
  29. SPOTlight on GLOW · Sarah Derks · 2023 · 12 citations · Cited by this paper
  30. Impact and effective management of nausea/vomiting on patients treated with zolbetuximab + chemotherapy: insights from the phase III SPOTLIGHT and GLOW studies · Kouhei Shitara · 2026 · 8 citations · Cited by this paper
  31. On evaluation of consistency in multi-regional clinical trials · Lisa Ying · 2017 · 6 citations · Cited by this paper
  32. Zolbetuximab on the SPOTLIGHT—a light spot? · Renata D’Alpino Peixoto · 2024 · 2 citations · Cited by this paper

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