Research map: Food enzyme safety: an extensive lineage of safe Aspergillus niger production strains

Papers in this map

1. Methods for detecting carcinogens and mutagens with the salmonella/mammalian-microsome mutagenicity test · Bruce N. Ames · 1975 · 7414 citations · Cited by this paper
2. Starch-derived oligosaccharides as prebiotics in innovative functional foods · Xingyuan Liu · 2026 · Cites this paper
3. In silico prediction of Ames mutagenicity for organosilicon compounds: Exploring and enhancing chemical space boundaries · 2026 · Related
4. Revised methods for the Salmonella mutagenicity test · Dorothy M. Maron · 1983 · 7397 citations · Cited by this paper
5. Standardization and Assessment of Acute Dermal Toxicity of an Ayurvedic Medicine Brihat Somraji Taila in Sprague-Dawley rats · 2026 · Related
6. Genome sequencing and analysis of the versatile cell factory Aspergillus niger CBS 513.88 · Herman J. Pel · 2007 · 1193 citations · Cited by this paper
7. Evaluating dosing guidelines for Ginkgo biloba: An evidence-based approach to standardisation · 2026 · Related
8. On the safety of Aspergillus niger - a review · E. Schuster · 2002 · 776 citations · Cited by this paper
9. Dietary intake and health risk characterization of cadmium, lead, and mercury in milkfish (Chanos chanos) and tilapia (Oreochromis spp.) from aquaculture farms surrounding Manila bay, Philippines · 2026 · Related
10. antiSMASH 8.0: extended gene cluster detection capabilities and analyses of chemistry, enzymology, and regulation · Kai Blin · 2025 · 661 citations · Cited by this paper
11. Polycyclic aromatic hydrocarbon (PAH) contamination in clinical nutrition: Levels and associated health risks in enteral nutrition formulas · 2026 · Related
12. Safety of the fungal workhorses of industrial biotechnology: update on the mycotoxin and secondary metabolite potential of Aspergillus niger, Aspergillus oryzae, and Trichoderma reesei · Jens C. Frisvad · 2018 · 384 citations · Cited by this paper
13. Automated extraction of toxicological mechanism of action from PubMed literature using Large Language Models · 2026 · Related
14. Fumonisin B2 Production by Aspergillus niger · Jens C. Frisvad · 2007 · 367 citations · Cited by this paper
15. Derivation of an occupational exposure limit (OEL) for a potent bispecific protein—Blinatumomab (BLINCYTO®) · 2026 · Related
16. How a fungus shapes biotechnology: 100 years of Aspergillus niger research · Timothy C. Cairns · 2018 · 348 citations · Cited by this paper
17. Microplastics in intravenous fluids: Occurrence, characterization, and risk indicators · 2026 · Related
18. Food-processing enzymes from recombinant microorganisms—a review · Zofia Olempska-Beer · 2006 · 332 citations · Cited by this paper
19. 40-week repeat-dose toxicity, toxicokinetics, and immunogenicity of efsubaglutide alfa following subcutaneous administration in cynomolgus monkeys · 2026 · Related
20. Fumonisin and Ochratoxin Production in Industrial Aspergillus niger Strains · Jens C. Frisvad · 2011 · 240 citations · Cited by this paper
21. Evaluation of subchronic toxicity, genotoxicity, and blood kinetics of 1,2-benzisothiazolin-3-one following oral administration · 2026 · Related
22. Evaluating the Safety of Microbial Enzyme Preparations Used in Food Processing: Update for a New Century · Michael W. Pariza · 2001 · 237 citations · Cited by this paper
23. Mycotoxins, mycotoxicoses, mycotoxicology andMycopathologia · Joan Wennstrom Bennett · 1987 · 177 citations · Cited by this paper
24. Molecular Mechanism of Lipotoxicity as an Interesting Aspect in the Development of Pathological States—Current View of Knowledge · Katarzyna Lipke · 2022 · 156 citations · Cited by this paper
25. Determining the Safety of Enzymes Used in Food Processing · Michael W. Pariza · 1983 · 123 citations · Cited by this paper
26. Scientific Opinion on the re-evaluation of butylated hydroxyanisole - BHA (E 320) as a food additive · EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS) · 2011 · 114 citations · Cited by this paper
27. Mode-of-Action Framework for Evaluating the Relevance of Rodent Forestomach Tumors in Cancer Risk Assessment · Deborah M. Proctor · 2007 · 86 citations · Cited by this paper
28. On the safety of a new generation of DSM Aspergillus niger enzyme production strains · Piet W. M. van Dijck · 2003 · 85 citations · Cited by this paper
29. Variation in the fumonisin biosynthetic gene cluster in fumonisin-producing and nonproducing black aspergilli · Antonia Susca · 2014 · 70 citations · Cited by this paper
30. Scientific Opinion on the re-evaluation of propionic acid (E 280), sodium propionate (E 281), calcium propionate (E 282) and potassium propionate (E 283) as food additives · EFSA Panel on Food additives and Nutrient Sources added to Food (ANS) · 2014 · 61 citations · Cited by this paper
31. Production of critic acid: A review · Abou‐Zeid A. Abou‐Zeid · 1984 · 45 citations · Cited by this paper
32. A Polyketide Synthase Encoded by the Gene An15g07920 Is Involved in the Biosynthesis of Ochratoxin A in Aspergillus niger · Jian Zhang · 2016 · 43 citations · Cited by this paper
33. Industrial microbial enzyme safety: What does the weight-of-evidence indicate? · Gregory S. Ladics · 2018 · 25 citations · Cited by this paper
34. On the need for confirmation of negative genotoxicity results in vitro and on the usefulness of mammalian cell mutation tests in a core battery: experiences of a contract research laboratory · David Kirkland · 1994 · 13 citations · Cited by this paper
35. Modified suspension Ames test for testing proteinaceous substances: An initial step · Hans Verhagen · 1994 · 13 citations · Cited by this paper
36. Assessment of the mode of action underlying development of forestomach tumors in rodents following oral exposure to ethyl acrylate and relevance to humans · Chad M. Thompson · 2018 · 12 citations · Cited by this paper
37. Aspergillus-associated diseases from an infectious diseases and allergological perspective · Jannik Stemler · 2024 · 4 citations · Cited by this paper

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