Research map: Iron-ing out ferroptosis-mediated T cell dysfunction in cancer

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Papers in this map

  1. Chimeric Antigen Receptor T Cells for Sustained Remissions in Leukemia · Shannon L. Maude · 2014 · 5491 citations · Cited by this paper
  2. Combined ctDNA and serum PSA for dynamic monitoring of metastatic prostate cancer starting first-line treatment: a prospective national cohort study · 2026 · Related
  3. Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia · Joseph A. Fraietta · 2018 · 1842 citations · Cited by this paper
  4. GABA signaling activation drives glioblastoma progression in female mice through myeloid-derived suppressor cells · 2026 · Related
  5. The cell biology of ferroptosis · Scott J. Dixon · 2024 · 1477 citations · Cited by this paper
  6. PAPOLA-mediated hyperactive polyadenylation promotes leukemogenesis and leukemia stem cell self-renewal through metabolic reprogramming · 2026 · Related
  7. T cell lipid peroxidation induces ferroptosis and prevents immunity to infection · Mai Matsushita · 2015 · 676 citations · Cited by this paper
  8. Adjuvant personalized multivalent neoantigen DNA vaccination for MGMT unmethylated glioblastoma: a phase 1 trial · 2026 · Related
  9. Selenium–GPX4 axis protects follicular helper T cells from ferroptosis · Yin Yao · 2021 · 385 citations · Cited by this paper
  10. Tumor irradiation promotes antigen dressing of dendritic cells to enhance CAR T cell persistence and efficacy in lung metastases · 2026 · Related
  11. FOXO1 is a master regulator of memory programming in CAR T cells · Alexander E. Doan · 2024 · 219 citations · Cited by this paper
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  13. Chronic lymphocytic leukemia cells impair mitochondrial fitness in CD8+ T cells and impede CAR T-cell efficacy · Jaco A. C. van Bruggen · 2019 · 193 citations · Cited by this paper
  14. Targeting PID1 generates oxysterols to switch macrophage cell fates for improved antitumor immunity · 2026 · Related
  15. Elevated transferrin receptor impairs T cell metabolism and function in systemic lupus erythematosus · Kelsey Voss · 2023 · 113 citations · Cited by this paper
  16. Bacterial engineering for cancer therapy · 2026 · Related
  17. GPX4 is a key ferroptosis regulator orchestrating T cells and CAR-T-cells sensitivity to ferroptosis · Marta Kłopotowska · 2025 · 23 citations · Cited by this paper
  18. A high-MAPK, low-WNT cell state drives metastatic dissemination in colorectal cancer · 2026 · Related
  19. Lipid metabolism drives dietary effects on T cell ferroptosis and immunity · Naiqi Wang · 2026 · 17 citations · Cited by this paper
  20. Iron overload in the tumor microenvironment induces CD8+ T cell ferroptosis and dysfunction · Zhenyu Lin · 2026 · 5 citations · Cited by this paper
  21. Iron-mediated ferroptosis impairs CAR-T cell function and antitumor efficacy · Delin Kong · 2026 · 2 citations · Cited by this paper
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