Research map: Contribution of monocyte subpopulations to the pathogenesis and therapy outcome of type 1 diabetes management in pediatric patients

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Papers in this map

  1. Gene expression profiling reveals the defining features of the classical, intermediate, and nonclassical human monocyte subsets · Kok Loon Wong · 2011 · 1127 citations · Cited by this paper
  2. A review of soluble mediator and cytokine networks linking combination immunotherapy, tumor microenvironment remodeling and skeletal muscle dysfunction · 2026 · Related
  3. Human Monocyte Subsets and Phenotypes in Major Chronic Inflammatory Diseases · Theodore S. Kapellos · 2019 · 928 citations · Cited by this paper
  4. GFI1 as a novel regulator of γδ T cell development and the IL-17/IFN-γ lineage commitment · 2026 · Related
  5. Increased Number of Islet-Associated Macrophages in Type 2 Diabetes · Jan A. Ehses · 2007 · 790 citations · Cited by this paper
  6. HIF-1α-centered metabolic reprogramming in osteoarthritis: cell type-specific effects and intercellular crosstalk among chondrocytes, BMSCs, and macrophages · 2026 · Related
  7. Type 1 diabetes mellitus as a disease of the β-cell (do not blame the immune system?) · Bart O. Roep · 2020 · 641 citations · Cited by this paper
  8. Acquired immune-mediated thrombotic thrombocytopenic purpura with severe cholestatic liver injury and reversible acute kidney injury after ivonescimab-containing chemoimmunotherapy: a case report and literature review · 2026 · Related
  9. Risk of Infection in Type 1 and Type 2 Diabetes Compared With the General Population: A Matched Cohort Study · Iain M. Carey · 2018 · 633 citations · Cited by this paper
  10. Lipoprotein (a) fuels EV71 replication by activating p38 MAPK-autophagy axis · 2026 · Related
  11. CD163 and Inflammation: Biological, Diagnostic, and Therapeutic Aspects · Anders Etzerodt · 2012 · 625 citations · Cited by this paper
  12. Delivery platforms for in vivo CAR-T engineering · 2026 · Related
  13. Hemoglobin Scavenger Receptor CD163 Mediates Interleukin-10 Release and Heme Oxygenase-1 Synthesis · Pandelis Philippidis · 2003 · 472 citations · Cited by this paper
  14. Envafolimab – novel anti-PD-1/PD-L1 antibody in cancer treatment · 2026 · Related
  15. Non-Classical monocytes display inflammatory features: Validation in Sepsis and Systemic Lupus Erythematous · Ratnadeep Mukherjee · 2015 · 446 citations · Cited by this paper
  16. Integrated plasma proteomics identifies HLA-G and osteopontin as circulating biomarkers of resistance to PD-1 inhibitor plus chemotherapy in choriocarcinoma · 2026 · Related
  17. Increased Toll-Like Receptor (TLR) 2 and TLR4 Expression in Monocytes from Patients with Type 1 Diabetes: Further Evidence of a Proinflammatory State · Sridevi Devaraj · 2007 · 376 citations · Cited by this paper
  18. Germline based SARS-CoV-2 specific B cell repertoire motif identified with novel sequence based bioinformatic pipeline · 2026 · Related
  19. The Role of Monocytes and Macrophages in Autoimmune Diseases: A Comprehensive Review · Wentao Ma · 2019 · 376 citations · Cited by this paper
  20. Defining nature, responses and drivers of regulatory- and conventional CD4+ T cells in the human term decidua · 2026 · Related
  21. The CD14 bright CD16+ monocyte subset is expanded in rheumatoid arthritis and promotes expansion of the Th17 cell population · Manuela Rossol · 2011 · 346 citations · Cited by this paper
  22. Monocytes from Patients with Type 1 Diabetes Spontaneously Secrete Proinflammatory Cytokines Inducing Th17 Cells · Elizabeth M. Bradshaw · 2009 · 303 citations · Cited by this paper
  23. Increased Monocytic Activity and Biomarkers of Inflammation in Patients With Type 1 Diabetes · Sridevi Devaraj · 2006 · 295 citations · Cited by this paper
  24. Classically and alternatively activated macrophages contribute to tissue remodelling after myocardial infarction · Christian Troidl · 2009 · 284 citations · Cited by this paper
  25. Targeting of CD163+ Macrophages in Inflammatory and Malignant Diseases · Maria Kløjgaard Skytthe · 2020 · 267 citations · Cited by this paper
  26. Pattern of human monocyte subpopulations in health and disease · Agnieszka Ożańska · 2020 · 251 citations · Cited by this paper
  27. Islet inflammation in type 2 diabetes · Marianne Böni‐Schnetzler · 2019 · 215 citations · Cited by this paper
  28. Development of autoantibodies precedes clinical manifestations of autoimmune diseases: A comprehensive review · Wen-Tao Ma · 2017 · 147 citations · Cited by this paper
  29. Identification of Novel Human Monocyte Subsets and Evidence for Phenotypic Groups Defined by Interindividual Variations of Expression of Adhesion Molecules · Fadila Merah‐Mourah · 2020 · 145 citations · Cited by this paper
  30. Increased Expression of CCL2 in Insulin-Producing Cells of Transgenic Mice Promotes Mobilization of Myeloid Cells From the Bone Marrow, Marked Insulitis, and Diabetes · Andrea P. Martin · 2008 · 117 citations · Cited by this paper
  31. Only the soluble form of the scavenger receptor CD163 acts inhibitory on phorbol ester‐activated T‐lymphocytes, whereas membrane‐bound protein has no effect · Werner Frings · 2002 · 105 citations · Cited by this paper
  32. Alterations in Monocyte CD16 in Association with Diabetes Complications · Danqing Min · 2012 · 81 citations · Cited by this paper
  33. Abnormal NF-κB Function Characterizes Human Type 1 Diabetes Dendritic Cells and Monocytes · Zia U.A. Mollah · 2008 · 71 citations · Cited by this paper
  34. Increase in Peripheral Blood Intermediate Monocytes is Associated with the Development of Recent-Onset Type 1 Diabetes Mellitus in Children · Xiaoya Ren · 2017 · 49 citations · Cited by this paper
  35. The Role of Soluble CD163 (sCD163) in Human Physiology and Pathophysiology · Andriana Plevriti · 2024 · 45 citations · Cited by this paper
  36. An increase in inflammation and islet dysfunction is a feature of prediabetes · Jessica R. Weaver · 2020 · 38 citations · Cited by this paper
  37. Immunological balance between Treg and Th17 lymphocytes as a key element of type 1 diabetes progression in children · Aleksandra Starosz · 2022 · 38 citations · Cited by this paper
  38. Monocyte CD163 is altered in association with diabetic complications: possible protective role · Danqing Min · 2016 · 31 citations · Cited by this paper
  39. Vitamin D3 Treatment Decreases Frequencies of CD16-Positive and TNF-α-Secreting Monocytes in Asthmatic Patients · Kamil Grubczak · 2015 · 24 citations · Cited by this paper

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