Research map: Efficacy of a SIRT1 Aptamer as an Anti-Angiogenic and Antioxidant Agent in in vitro, ex vivo, and in vivo Models

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  1. Tumor Angiogenesis: Therapeutic Implications · Louis M. Sherwood · 1971 · 10246 citations · Cited by this paper
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  15. Antioxidants: a comprehensive review · İlhami Gülçın · 2025 · 363 citations · Cited by this paper
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  17. SirT1 Regulation of Antioxidant Genes Is Dependent on the Formation of a FoxO3a/PGC-1α Complex · Yolanda Olmos · 2013 · 316 citations · Cited by this paper
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  20. Dual Tumor Suppressor and Tumor Promoter Action of Sirtuins in Determining Malignant Phenotype · Vincenzo Carafa · 2019 · 200 citations · Cited by this paper
  21. SIRT1 deacetylates and stabilizes hypoxia-inducible factor-1α (HIF-1α) via direct interactions during hypoxia · Hyun-Yoo Joo · 2015 · 145 citations · Cited by this paper
  22. New Insights into Aptamers: An Alternative to Antibodies in the Detection of Molecular Biomarkers · Michaela Domšicová · 2024 · 134 citations · Cited by this paper
  23. A Molecular Perspective on HIF-1α and Angiogenic Stimulator Networks and Their Role in Solid Tumors: An Update · Anuja Gajanan Magar · 2024 · 129 citations · Cited by this paper
  24. The aortic ring model of angiogenesis: a quarter century of search and discovery · Roberto Francesco Nicosia · 2009 · 127 citations · Cited by this paper
  25. Oxidative stress-induced angiogenesis · Yujing Huang · 2019 · 123 citations · Cited by this paper
  26. Emerging roles of SIRT1 activator, SRT2104, in disease treatment · Ning Chang · 2024 · 100 citations · Cited by this paper
  27. Human Endothelial Cell Spheroid-based Sprouting Angiogenesis Assay in Collagen · Fabian Tetzlaff · 2018 · 85 citations · Cited by this paper
  28. A potential role for reactive oxygen species and the HIF-1α–VEGF pathway in hypoxia-induced pulmonary vascular leak · David C. Irwin · 2009 · 80 citations · Cited by this paper
  29. Mechanisms of angiogenesis in tumour · Run Zhang · 2024 · 76 citations · Cited by this paper
  30. A Systematic Review on Advances in Management of Oxidative Stress-Associated Cardiovascular Diseases · Soyeon Jin · 2024 · 72 citations · Cited by this paper
  31. In vitro antioxidant activity of pet ether extract of black pepper · Ramnik Singh · 2008 · 69 citations · Cited by this paper
  32. Intracellular endothelial cell metabolism in vascular function and dysfunction · Kathryn M. Citrin · 2024 · 69 citations · Cited by this paper
  33. Recent advances in aptamer discovery, modification and improving performance · Arezoo Fallah · 2024 · 62 citations · Cited by this paper
  34. SIRT1 mediated inhibition of VEGF/VEGFR2 signaling by Resveratrol and its relevance to choroidal neovascularization · Huiming Zhang · 2015 · 60 citations · Cited by this paper
  35. A Molecular Perspective on Sirtuin Activity · Carla S. Silva Teixeira · 2020 · 55 citations · Cited by this paper
  36. Oxidative Stress and Cerebral Vascular Tone: The Role of Reactive Oxygen and Nitrogen Species · Michele Salvagno · 2024 · 53 citations · Cited by this paper
  37. Angiogenesis modulation by exogenous antioxidants · Dorota Magdalena Radomska-Leśniewska · 2017 · 47 citations · Cited by this paper
  38. Role of Sirtuins in Tumor Angiogenesis · Lincy Edatt · 2020 · 45 citations · Cited by this paper
  39. Microvascular Experimentation in the Chick Chorioallantoic Membrane as a Model for Screening Angiogenic Agents including from Gene-Modified Cells · Donna C. Kennedy · 2021 · 43 citations · Cited by this paper

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