Research map: Complement augments antibody neutralization of SARS-CoV-2 variants
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Papers in this map
Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody
· Dora Pinto · 2020 · 2164 citations · Cited by this paper
Premature senescence impairs hematopoietic stem cell function during sickle cell disease in mice and humans
· Aditya Barve · 2026 · 2 citations · Related
Considerable escape of SARS-CoV-2 Omicron to antibody neutralization
· Delphine Planas · 2021 · 1625 citations · Cited by this paper
Clinical validation of an HPV whole-genome sequencing assay for MRD detection in patients with HPV+ head and neck cancer treated with surgery
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Complement System Part I – Molecular Mechanisms of Activation and Regulation
· Nicolas S. Merle · 2015 · 1624 citations · Cited by this paper
Cancer-induced nerve injury unveils a sympathetic-to-sensory nerve axis in a mouse model of head and neck squamous cell carcinoma
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A neutralizing human antibody binds to the N-terminal domain of the Spike protein of SARS-CoV-2
· Xiangyang Chi · 2020 · 1584 citations · Cited by this paper
KSHV-infected endothelial cells expand and up-regulate angiogenic pathways and CXCR4 in patient-derived Kaposi sarcoma models
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· Katherine McMahan · 2020 · 1240 citations · Cited by this paper
PTEN acts as a master mediator of nonhealing venous leg ulcers by suppressing immune response, angiogenesis, and lymphangiogenesis
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Potently neutralizing and protective human antibodies against SARS-CoV-2
· Seth J. Zost · 2020 · 1200 citations · Cited by this paper
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IgA dominates the early neutralizing antibody response to SARS-CoV-2
· Delphine Sterlin · 2020 · 1145 citations · Cited by this paper
Engineered antibodies bypass bacterial immune evasion to drive complement-mediated protection against lethal infections
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Molecular Architecture of the SARS-CoV-2 Virus
· Hangping Yao · 2020 · 1128 citations · Cited by this paper
Heterogeneous human muscle fibroadipogenic progenitors include a DLK1 + subpopulation that prevents fatty infiltration after injury
· 2026 · Related
Fc receptor but not complement binding is important in antibody protection against HIV
· Ann Jones Hessell · 2007 · 917 citations · Cited by this paper
Cytokine-mediated activation of kidney-infiltrating CD8 + T cells enables their contribution to inflammation in human lupus nephritis
· 2026 · Related
Complement Is Activated by IgG Hexamers Assembled at the Cell Surface
· Christoph A. Diebolder · 2014 · 821 citations · Cited by this paper
The pyrrolidinamide antimalarial drug MMV367 rapidly clears blood-stage Plasmodium falciparum in healthy adults with experimental malaria
· 2026 · Related
Structural biology of SARS-CoV-2 and implications for therapeutic development
· Haitao Yang · 2021 · 586 citations · Cited by this paper
Syncytia formation by SARS‐CoV‐2‐infected cells
· Julian Buchrieser · 2020 · 519 citations · Cited by this paper
Broadly neutralizing antibodies to SARS-CoV-2 and other human coronaviruses
· Yanjia Chen · 2022 · 415 citations · Cited by this paper
Broad and potent activity against SARS-like viruses by an engineered human monoclonal antibody
· C. Garrett Rappazzo · 2021 · 393 citations · Cited by this paper
Lectins enhance SARS-CoV-2 infection and influence neutralizing antibodies
· Florian A. Lempp · 2021 · 330 citations · Cited by this paper
Broadly neutralizing antibodies target the coronavirus fusion peptide
· Cherrelle Dacon · 2022 · 279 citations · Cited by this paper
Natural Antibody and Complement Mediate Neutralization of Influenza Virus in the Absence of Prior Immunity
· Jerome P. Jayasekera · 2007 · 268 citations · Cited by this paper
Distinct evolution of SARS-CoV-2 Omicron XBB and BA.2.86/JN.1 lineages combining increased fitness and antibody evasion
· Delphine Planas · 2024 · 256 citations · Cited by this paper
Increased complement activation is a distinctive feature of severe SARS-CoV-2 infection
· Lina Ma · 2021 · 237 citations · Cited by this paper
A Novel Platform for the Potentiation of Therapeutic Antibodies Based on Antigen-Dependent Formation of IgG Hexamers at the Cell Surface
· Rob N. de Jong · 2016 · 233 citations · Cited by this paper
Resistance of Omicron subvariants BA.2.75.2, BA.4.6, and BQ.1.1 to neutralizing antibodies
· Delphine Planas · 2023 · 205 citations · Cited by this paper
Rational identification of potent and broad sarbecovirus-neutralizing antibody cocktails from SARS convalescents
· Yunlong Cao · 2022 · 177 citations · Cited by this paper
Analysis of memory B cells identifies conserved neutralizing epitopes on the N-terminal domain of variant SARS-Cov-2 spike proteins
· Zijun Wang · 2022 · 167 citations · Cited by this paper
Neutralization mechanism of a human antibody with pan-coronavirus reactivity including SARS-CoV-2
· Xiaoyu Sun · 2022 · 159 citations · Cited by this paper
Recognition and inhibition of SARS-CoV-2 by humoral innate immunity pattern recognition molecules
· Matteo Stravalaci · 2022 · 158 citations · Cited by this paper
Anti-C5a antibody (vilobelimab) therapy for critically ill, invasively mechanically ventilated patients with COVID-19 (PANAMO): a multicentre, double-blind, randomised, placebo-controlled, phase 3 trial
· Alexander P. J. Vlaar · 2022 · 153 citations · Cited by this paper
Multiplex assays for the identification of serological signatures of SARS-CoV-2 infection: an antibody-based diagnostic and machine learning study
· Jason Rosado · 2020 · 125 citations · Cited by this paper
FCM PASS Software Aids Extracellular Vesicle Light Scatter Standardization
· Joshua A Welsh · 2019 · 90 citations · Cited by this paper
Early cross-coronavirus reactive signatures of humoral immunity against COVID-19
· Paulina Kapłonek · 2021 · 88 citations · Cited by this paper
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