Research map: Myrtenol modulates TWEAK/TLR4–NF-κB, miR-21, PTEN, and ERK-1 expressions and improves behavioral outcomes in a rat glioblastoma model

Back to the article

Papers in this map

  1. Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method · Kenneth J. Livak · 2001 · 185110 citations · Cited by this paper
  2. Lipid-based nanocarrier-enabled combination therapy for breast cancer: overcoming drug resistance toward precision oncology · 2026 · Related
  3. Tumour-associated macrophages as treatment targets in oncology · Alberto Mantovani · 2017 · 4192 citations · Cited by this paper
  4. Apoptosis-inducing potential of tilorone dihydrochloride in triple-negative breast cancer: in silico and in vitro evidences · 2026 · Related
  5. MicroRNA-21 Regulates Expression of the PTEN Tumor Suppressor Gene in Human Hepatocellular Cancer · Fanyin Meng · 2007 · 2792 citations · Cited by this paper
  6. EPA-loaded silica nanoemulsions attenuate DEN-induced hepatic fibroinflammation by modulating homocysteine, PKCα/NF-κB, and Nrf2 signaling · 2026 · Related
  7. MicroRNA-21 Is an Antiapoptotic Factor in Human Glioblastoma Cells · Jennifer Ai-wen Chan · 2005 · 2565 citations · Cited by this paper
  8. Cycloastragenol overcomes trastuzumab resistance in HER2-positive breast cancer by regulating cell cycle and epithelial-mesenchymal transition through EZH2/PTEN/AKT pathway · 2026 · Related
  9. The role of microglia and macrophages in glioma maintenance and progression · Dolores Hambardzumyan · 2015 · 1742 citations · Cited by this paper
  10. Exploring betanin regulatory impact on TGF-β and PI3K/AKT pathways in oral cancer · 2026 · Related
  11. Microglia as a source and target of cytokines · Uwe‐Karsten Hanisch · 2002 · 1672 citations · Cited by this paper
  12. Protective effects of ginseng against reproductive injury: mechanisms and research progress · 2026 · Related
  13. Essential Oils in Combination and Their Antimicrobial Properties · Imaël Henri Nestor Bassolé · 2012 · 1327 citations · Cited by this paper
  14. Development of citrinin-loaded liposomes and in vitro toxicogenetic evaluation on breast cells · 2026 · Related
  15. Neurobiology of rodent self-grooming and its value for translational neuroscience · Allan V. Kalueff · 2015 · 898 citations · Cited by this paper
  16. Luteolin alleviates inflammation by inhibiting the PI3K-Akt-FOXO3a pathway · 2026 · Related
  17. MicroRNA 21 Promotes Glioma Invasion by Targeting Matrix Metalloproteinase Regulators · Galina Gabriely · 2008 · 891 citations · Cited by this paper
  18. Novel copper–phenothiazine–amino acid complexes exhibit selective anticancer activity via induction of apoptosis and cell cycle arrest in HepG2 cells · 2026 · Related
  19. MicroRNA-21 Targets a Network of Key Tumor-Suppressive Pathways in Glioblastoma Cells · Thales Y. Papagiannakopoulos · 2008 · 709 citations · Cited by this paper
  20. Targeting early pulmonary fibrosis with bone marrow mesenchymal stem cells and their derived exosomes: a comparative study of inhalation versus injection delivery in bleomycin-induced rat lung injury · 2026 · Related
  21. A Review on Anti-Inflammatory Activity of Monoterpenes · Rita de Cássia da Silveira e Sá · 2013 · 556 citations · Cited by this paper
  22. Understanding the immunosuppressive microenvironment of glioma: mechanistic insights and clinical perspectives · Hao Lin · 2024 · 378 citations · Cited by this paper
  23. Neuroinflammation induces anxiety- and depressive-like behavior by modulating neuronal plasticity in the basolateral amygdala · Zhi-Heng Zheng · 2020 · 307 citations · Cited by this paper
  24. Glioblastoma at the crossroads: current understanding and future therapeutic horizons · Shilpi Singh · 2025 · 272 citations · Cited by this paper
  25. Glioblastoma multiforme: insights into pathogenesis, key signaling pathways, and therapeutic strategies · Ashkan Pouyan · 2025 · 271 citations · Cited by this paper
  26. MicroRNA-21 inhibitor sensitizes human glioblastoma cells U251 (PTEN-mutant) and LN229 (PTEN-wild type) to taxol · Yu Ren · 2010 · 218 citations · Cited by this paper
  27. The Interleukin-10 Family of Cytokines and Their Role in the CNS · Amanda Rae Burmeister · 2018 · 216 citations · Cited by this paper
  28. The Tumor Necrosis Factor-like Weak Inducer of Apoptosis (TWEAK)-Fibroblast Growth Factor-inducible 14 (Fn14) Signaling System Regulates Glioma Cell Survival via NFκB Pathway Activation and BCL-XL/BCL-W Expression · Nhan L. Tran · 2004 · 179 citations · Cited by this paper
  29. PTEN deficiency reprogrammes human neural stem cells towards a glioblastoma stem cell-like phenotype · Shunlei Duan · 2015 · 176 citations · Cited by this paper
  30. Progress in targeting PTEN/PI3K/Akt axis in glioblastoma therapy: Revisiting molecular interactions · Mehrdad Hashemi · 2023 · 160 citations · Cited by this paper
  31. DNA Damage Induces NF-κB-dependent MicroRNA-21 Up-regulation and Promotes Breast Cancer Cell Invasion · Jixiao Niu · 2012 · 154 citations · Cited by this paper
  32. Targeting NF-κB in glioblastoma: A therapeutic approach · Dinorah Friedmann‐Morvinski · 2016 · 144 citations · Cited by this paper
  33. The Human Fn14 Receptor Gene Is Up-Regulated in Migrating Glioma Cells in Vitro and Overexpressed in Advanced Glial Tumors · Nhan L. Tran · 2003 · 143 citations · Cited by this paper
  34. Toll-like receptors and toll-like receptor-targeted immunotherapy against glioma · Yang Xun · 2021 · 136 citations · Cited by this paper
  35. Glioblastoma hijacks microglial gene expression to support tumor growth · Sybren L. N. Maas · 2020 · 135 citations · Cited by this paper
  36. Understanding the role of cytokines in Glioblastoma Multiforme pathogenesis · Vivian F. Zhu · 2011 · 125 citations · Cited by this paper
  37. Preclinical development and clinical use of perillyl alcohol for chemoprevention and cancer therapy. · Thomas C. Chen · 2015 · 120 citations · Cited by this paper
  38. Anticancer activity of limonene: A systematic review of target signaling pathways · Heitor G. Araújo-Filho · 2021 · 116 citations · Cited by this paper
  39. PI3K/AKT signaling and neuroprotection in ischemic stroke: molecular mechanisms and therapeutic perspectives · Tianlong Liu · 2024 · 107 citations · Cited by this paper

Source: OpenAlex (CC0)