Research map: Polyamines are i-Motif disruptors

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  1. HELIX FORMATION BY GUANYLIC ACID · Martin F. Gellert · 1962 · 1662 citations · Cited by this paper
  2. Decoding preeclampsia: A fusion of multi-view machine learning and multi-omics to identify putative inflammation-related mechanisms · 2026 · Related
  3. Structure of a B-DNA dodecamer: conformation and dynamics. · Horace R. Drew · 1981 · 1571 citations · Cited by this paper
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  5. A tetrameric DNA structure with protonated cytosine-cytosine base pairs · Kalle Gehring · 1993 · 1255 citations · Cited by this paper
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  7. Polyamines in cell growth and cell death: molecular mechanisms and therapeutic applications · Thresia Thomas · 2001 · 870 citations · Cited by this paper
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  10. Neonatal expression of human FMRP isoform corrects cortical deficits and improves behavior in a mouse model of fragile X syndrome · 2026 · Related
  11. I-motif DNA structures are formed in the nuclei of human cells · Mahdi Zeraati · 2018 · 586 citations · Cited by this paper
  12. Intranasal Tat-modified PEG-PCL nanomicelles delivering anti-RelA siRNA attenuate ischemia-reperfusion injury in transient MCAO mice · 2026 · Related
  13. Polyamines in aging and disease · Nadège Minois · 2011 · 522 citations · Cited by this paper
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  15. Structure of the intramolecular human telomeric G-quadruplex in potassium solution: a novel adenine triple formation · Jixun Dai · 2007 · 398 citations · Cited by this paper
  16. To scramble or not: steric blocking 2′-MOE/PS control antisense oligonucleotides across cellular models · 2026 · Related
  17. The Dynamic Character of the BCL2 Promoter i-Motif Provides a Mechanism for Modulation of Gene Expression by Compounds That Bind Selectively to the Alternative DNA Hairpin Structure · Samantha L. Kendrick · 2014 · 290 citations · Cited by this paper
  18. ADAR RNA editing for cardiovascular disease: Targeting B4GALT1 to modulate lipid metabolism through reduced galactosyltransferase activity · 2026 · Related
  19. The Transcriptional Complex Between the BCL2 i-Motif and hnRNP LL Is a Molecular Switch for Control of Gene Expression That Can Be Modulated by Small Molecules · Hyun-Jin Kang · 2014 · 259 citations · Cited by this paper
  20. Evaluation of lipid nanoparticle adjuvants with different PEG lipid ratios and phospholipid modifications in non-human primates · 2026 · Related
  21. Polyamines: Functions, Metabolism, and Role in Human Disease Management · Narashans Alok Sagar · 2021 · 207 citations · Cited by this paper
  22. Biosynthesis of polyamines and polyamine-containing molecules · Anthony J. Michael · 2016 · 192 citations · Cited by this paper
  23. DNA G-Quadruplex and i-Motif Structure Formation Is Interdependent in Human Cells · Jessica J. King · 2020 · 145 citations · Cited by this paper
  24. I-Motif formation in gene promoters: unusually stable formation in sequences complementary to known G-quadruplexes · John Brazier · 2012 · 124 citations · Cited by this paper
  25. Genome-wide mapping of i-motifs reveals their association with transcription regulation in live human cells · Irene Zanin · 2023 · 109 citations · Cited by this paper
  26. Spermidine delays aging in humans · Frank Madeo · 2018 · 96 citations · Cited by this paper
  27. The i-Motif as a Molecular Target: More Than a Complementary DNA Secondary Structure · Susie L. Brown · 2021 · 96 citations · Cited by this paper
  28. pH-Dependent Structures of an i-Motif DNA in Solution · Kyeong Sik Jin · 2009 · 76 citations · Cited by this paper
  29. Compartmentalization of polyamines in mammalian cells · Michael Mach · 1982 · 48 citations · Cited by this paper
  30. Crystal and molecular structure of a DNA fragment: d(CGTGAATTCACG) · Narendra Narayana · 1991 · 47 citations · Cited by this paper
  31. i-Motif DNA: identification, formation, and cellular functions · Shentong Tao · 2024 · 44 citations · Cited by this paper
  32. i-Motif of cytosine-rich human telomere DNA fragments containing natural base lesions · Zuzana Dvořáková · 2018 · 41 citations · Cited by this paper
  33. Structural insights into i-motif DNA structures in sequences from the insulin-linked polymorphic region · Dilek Guneri · 2024 · 41 citations · Cited by this paper
  34. Pattern preferences of DNA nucleotide motifs by polyamines putrescine2+, spermidine3+ and spermine4+ · Sergiy M. Perepelytsya · 2019 · 33 citations · Cited by this paper
  35. Effects of Polyamine Binding on the Stability of DNA i-Motif Structures · Michael M. Molnar · 2019 · 23 citations · Cited by this paper
  36. i-Motifs as regulatory switches: Mechanisms and implications for gene expression · Auroni Deep · 2025 · 19 citations · Cited by this paper
  37. Polyamines in the Developing Mouse Brain · Thomas W. Jasper · 2007 · 18 citations · Cited by this paper
  38. Identification of multiple genomic DNA sequences which form i-motif structures at neutral pH · Elisé P. Wright · 2017 · 13 citations · Cited by this paper
  39. Chemically modified CRISPR-Cas9 enables targeting of individual G-quadruplex and i-motif structures, revealing ligand-dependent transcriptional perturbation · Sabrina Pia Nuccio · 2025 · 13 citations · Cited by this paper

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