Research map: Recent advances in screening, diagnosis, prognosis and personalized treatment of sepsis

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Papers in this map

  1. Genomic landscape of the individual host response and outcomes in sepsis: a prospective cohort study · Emma E. Davenport · 2016 · 887 citations · Cited by this paper
  2. Epidemiological, clinical and immunological features of Schistosoma spp., Stronglyoides stercoralis and Taenia spp. infections in Ghanaian HIV patients · 2025 · Related
  3. Classification of patients with sepsis according to blood genomic endotype: a prospective cohort study · Brendon P. Scicluna · 2017 · 691 citations · Cited by this paper
  4. Gall bladder sludge and biliary pseudolithiasis as rare complications of ceftriaxone therapy in adult patients – A case report including sonographic workup · 2025 · Related
  5. Unsupervised Analysis of Transcriptomics in Bacterial Sepsis Across Multiple Datasets Reveals Three Robust Clusters · Timothy E. Sweeney · 2018 · 388 citations · Cited by this paper
  6. Genetic characterization of blaNDM-1-positive Klebsiella quasipneumoniae subsp. similipneumoniae from a human carrier · 2026 · Related
  7. Transcriptomic Signatures in Sepsis and a Differential Response to Steroids. From the VANISH Randomized Trial · David Benjamin Antcliffe · 2018 · 375 citations · Cited by this paper
  8. Distinct antibiotic treatment regimens differentially affect colonization resistance against multi-drug resistant Pseudomonas aeruginosa in mice · 2025 · Related
  9. Molecular diagnosis of sepsis: New aspects and recent developments · Oliver Liesenfeld · 2014 · 221 citations · Cited by this paper
  10. Structural biology of Nipah virus G and F glycoproteins: Insights into therapeutic and vaccine development · 2025 · Related
  11. The Next Generation of Sepsis Clinical Trial Designs · Steven M. Opal · 2014 · 199 citations · Cited by this paper
  12. Evaluation of a commercial real-time PCR assay targeting Leishmania spp. with microscopically positive skin biopsies obtained from Nigerian patients · 2026 · Related
  13. Global, regional, and national sepsis incidence and mortality, 1990–2021: a systematic analysis · Authia P Gray · 2025 · 199 citations · Cited by this paper
  14. Effects of a clinical metagenomics intervention on clinical outcomes, healthcare costs, and health-related quality of life in patients with sepsis or septic shock: results of the randomized-controlled DigiSep trial · 2026 · Related
  15. Infectious Diseases Society of America (IDSA) POSITION STATEMENT: Why IDSA Did Not Endorse the Surviving Sepsis Campaign Guidelines · IDSA Sepsis Task Force · 2017 · 181 citations · Cited by this paper
  16. Rapid diagnosis of common, undetected, and uncultivable bloodstream infections from positive blood cultures using Oxford Nanopore sequencing: a metagenomic pipeline analysis · 2026 · Related
  17. Integrated host-microbe plasma metagenomics for sepsis diagnosis in a prospective cohort of critically ill adults · Katrina Kalantar · 2022 · 158 citations · Cited by this paper
  18. The Global Impact of Sepsis: Epidemiology, Recognition, Management, and Health System Challenges · 2026 · Related
  19. SIRS, SOFA, qSOFA, and NEWS in the diagnosis of sepsis and prediction of adverse outcomes: a systematic review and meta-analysis · Xia Qiu · 2023 · 144 citations · Cited by this paper
  20. Implementation of pathogen genomics in clinical microbiology laboratories · 2026 · Related
  21. Development and Validation of the Sequential Organ Failure Assessment (SOFA)-2 Score · Otavio Ranzani · 2025 · 135 citations · Cited by this paper
  22. Biomarker-Guided Antibiotic Duration for Hospitalized Patients With Suspected Sepsis · Paul M Dark · 2024 · 105 citations · Cited by this paper
  23. Sepsis Alert Systems, Mortality, and Adherence in Emergency Departments · Hyung‐Jun Kim · 2024 · 86 citations · Cited by this paper
  24. Precision Immunotherapy to Improve Sepsis Outcomes · Evangelos J. Giamarellos‐Bourboulis · 2025 · 84 citations · Cited by this paper
  25. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2026 · Hallie C. Prescott · 2026 · 75 citations · Cited by this paper
  26. FDA-Authorized AI/ML Tool for Sepsis Prediction: Development and Validation · Akhil S. Bhargava · 2024 · 72 citations · Cited by this paper
  27. A consensus immune dysregulation framework for sepsis and critical illnesses · Andrew Reese Moore · 2025 · 71 citations · Cited by this paper
  28. Lactate and Lactylation in Sepsis: A Comprehensive Review · Sijia Liu · 2024 · 64 citations · Cited by this paper
  29. Diagnosis of bacterial sepsis: why are tests for bacteremia not sufficient? · Timothy E. Sweeney · 2019 · 62 citations · Cited by this paper
  30. Metagenomic Next-Generation Sequencing in Infectious Diseases: Clinical Applications, Translational Challenges, and Future Directions · Ayman Elbehiry · 2025 · 60 citations · Cited by this paper
  31. A consensus blood transcriptomic framework for sepsis · Brendon P. Scicluna · 2025 · 53 citations · Cited by this paper
  32. The immunology of sepsis: translating new insights into clinical practice · Matthijs Kox · 2025 · 51 citations · Cited by this paper
  33. The Optimization and Biological Significance of a 29-Host-Immune-mRNA Panel for the Diagnosis of Acute Infections and Sepsis · Yudong D. He · 2021 · 48 citations · Cited by this paper
  34. Early Administration of Antibiotics for Suspected Sepsis · Michael Mi · 2019 · 47 citations · Cited by this paper
  35. Corticosteroids in Sepsis and Septic Shock: A Systematic Review, Pairwise, and Dose-Response Meta-Analysis · Tyler Pitre · 2024 · 45 citations · Cited by this paper
  36. Transforming sepsis management: AI-driven innovations in early detection and tailored therapies · Praveen Papareddy · 2025 · 44 citations · Cited by this paper
  37. The American Society for Microbiology’s evidence-based laboratory medicine practice guidelines for the diagnosis of bloodstream infections using rapid tests: a systematic review and meta-analysis · Donna M. Wolk · 2025 · 43 citations · Cited by this paper
  38. Development and validation of a cellular host response test as an early diagnostic for sepsis · Lionel Guillou · 2021 · 41 citations · Cited by this paper
  39. Improving Sepsis Outcomes in the Era of Pay-for-Performance and Electronic Quality Measures: A Joint IDSA/ACEP/PIDS/SHEA/SHM/SIDP Position Paper · Chanu Rhee · 2023 · 40 citations · Cited by this paper

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