Effects of a clinical metagenomics intervention on clinical outcomes, healthcare costs, and health-related quality of life in patients with sepsis or septic shock: results of the randomized-controlled DigiSep trial

Intensive Care Medicine · Published 2026-06-30 · DOI 10.1007/s00134-026-08521-3

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Authors (51)

Thorsten Brenner, Annabell Skarabis, Stefan J. Schaller, Thilo von Groote, Christian Putensen, Ulf Günther, Martin Sauer, Sebastian O. Decker, Fabian Dusse, Manfred Weiss, Klaudiusz Suchodolski, Tim-Philipp Simon, Peter Rosenberger, Onnen Moerer, Matthias Unterberg, Jens-Christian Schewe, Hendrik Bracht, Selina Hutzl, Manuel Feißt, Ursula Marschall, Patrick Brandenburg, Philip Stevens, Juliana Schmidt, Mathias W. Pletz, Marc M. Berger, on behalf of the German Society of Anaesthesiology and Intensive Care (GSAIC) Trials Group, Jens Brands, Alberto Antinoro, Linus O. Warner, Markus A. Weigand, Dominique M. Hart, Gernot Marx, Jana Mossanen, Thomas Breuer, Helene Häberle, Kristina Nitzsche, Paul Thalmann, Jolanda Brezinski, Joachim Saam, Silke Grumaz, Maren Steinmann, Maxime Gaasch, Bastian Pasieka, Ulrike Jaekel, Timo Brandenburger, Friedhelm Bach, Haitham Mutlak, Stefan Utzolino, Wolfgang A. Krueger, Stefan Hagel, Christian Lanckohr

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Publication details

Year
2026

Citation

Brenner, T., Skarabis, A., Schaller, S., et al. (2026). Effects of a clinical metagenomics intervention on clinical outcomes, healthcare costs, and health-related quality of life in patients with sepsis or septic shock: results of the randomized-controlled DigiSep trial. Intensive Care Medicine. https://doi.org/10.1007/s00134-026-08521-3

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