Research map: GFI1 as a novel regulator of γδ T cell development and the IL-17/IFN-γ lineage commitment

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  1. Fast, sensitive and accurate integration of single-cell data with Harmony · Ilya Korsunsky · 2019 · 11385 citations · Cited by this paper
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  13. CD27 is a thymic determinant of the balance between interferon-γ- and interleukin 17–producing γδ T cell subsets · Julie C. Ribot · 2009 · 645 citations · Cited by this paper
  14. Integrated plasma proteomics identifies HLA-G and osteopontin as circulating biomarkers of resistance to PD-1 inhibitor plus chemotherapy in choriocarcinoma · 2026 · Related
  15. γδ T cells in tissue physiology and surveillance · Julie C. Ribot · 2020 · 542 citations · Cited by this paper
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  17. GATA-3 promotes Th2 responses through three different mechanisms: induction of Th2 cytokine production, selective growth of Th2 cells and inhibition of Th1 cell-specific factors · Jinfang Zhu · 2006 · 488 citations · Cited by this paper
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  19. Heterogeneity among DN1 Prothymocytes Reveals Multiple Progenitors with Different Capacities to Generate T Cell and Non-T Cell Lineages · Helen E. Porritt · 2004 · 433 citations · Cited by this paper
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  21. Epigenetic Regulation of Hematopoietic Differentiation by Gfi-1 and Gfi-1b Is Mediated by the Cofactors CoREST and LSD1 · Shireen Saleque · 2007 · 399 citations · Cited by this paper
  22. γδ T cells: origin and fate, subsets, diseases and immunotherapy · Yi Hu · 2023 · 379 citations · Cited by this paper
  23. Development of Interleukin-17-Producing γδ T Cells Is Restricted to a Functional Embryonic Wave · Jan D. Haas · 2012 · 353 citations · Cited by this paper
  24. Transcription factor Gfi1 regulates self‐renewal and engraftment of hematopoietic stem cells · Hui Zeng · 2004 · 339 citations · Cited by this paper
  25. PI3K-Akt-mTORC1-S6K1/2 Axis Controls Th17 Differentiation by Regulating Gfi1 Expression and Nuclear Translocation of RORγ · Yutaka Kurebayashi · 2012 · 327 citations · Cited by this paper
  26. Inflammatory reactions and severe neutropenia in mice lacking the transcriptional repressor Gfi1 · Holger Karsunky · 2002 · 323 citations · Cited by this paper
  27. Gfi -1 Encodes a Nuclear Zinc Finger Protein That Binds DNA and Functions as a Transcriptional Repressor · Patrick A. Zweidler‐McKay · 1996 · 314 citations · Cited by this paper
  28. Solo: Doublet Identification in Single-Cell RNA-Seq via Semi-Supervised Deep Learning · Nicholas Bernstein · 2020 · 309 citations · Cited by this paper
  29. The Gfi-1 Proto-Oncoprotein Contains a Novel Transcriptional Repressor Domain, SNAG, and Inhibits G 1 Arrest Induced by Interleukin-2 Withdrawal · H. Leighton Grimes · 1996 · 281 citations · Cited by this paper
  30. Commitment and Developmental Potential of Extrathymic and Intrathymic T Cell Precursors: Plenty to Choose from · Avinash Bhandoola · 2007 · 278 citations · Cited by this paper
  31. Cutting Edge: Identification of a Motile IL-17–Producing γδ T Cell Population in the Dermis · Elizabeth E. Gray · 2011 · 265 citations · Cited by this paper
  32. GFI1 proteins orchestrate the emergence of haematopoietic stem cells through recruitment of LSD1 · Roshana Thambyrajah · 2015 · 228 citations · Cited by this paper
  33. Deficiency in IL-17-committed Vγ4+ γδ T cells in a spontaneous Sox13-mutant CD45.1+ congenic mouse substrain provides protection from dermatitis · Elizabeth E. Gray · 2013 · 223 citations · Cited by this paper
  34. Gfi1 and Gfi1b: key regulators of hematopoiesis · Laurens T. van der Meer · 2010 · 215 citations · Cited by this paper
  35. Growth Factor Independent-1 Induced by IL-4 Regulates Th2 Cell Proliferation · Jinfang Zhu · 2002 · 215 citations · Cited by this paper
  36. LSD1: Biologic Roles and Therapeutic Targeting · Alba Maiqués-Díaz · 2016 · 213 citations · Cited by this paper
  37. Inflammation induces dermal Vγ4 + γδT17 memory-like cells that travel to distant skin and accelerate secondary IL-17–driven responses · Francisco Ramírez‐Valle · 2015 · 211 citations · Cited by this paper
  38. A Recurrent Network Involving the Transcription Factors PU.1 and Gfi1 Orchestrates Innate and Adaptive Immune Cell Fates · Chauncey J. Spooner · 2009 · 193 citations · Cited by this paper
  39. Identification of CD25+ γδ T Cells As Fetal Thymus-Derived Naturally Occurring IL-17 Producers · Kensuke Shibata · 2008 · 182 citations · Cited by this paper

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