Research map: Transdermal Curcumin Gel (VAS-101 Drug Candidate) Improves the Microcirculation and Tissue Oxygenation in a Rat Model of Sickle Cell Vaso-Occlusive Episode

Back to the article

Papers in this map

  1. Curcumin: A Review of Its Effects on Human Health · Susan Joyce Hewlings · 2017 · 2695 citations · Cited by this paper
  2. Altered Sensory-Pain Transitions in Sickle Cell Disease Reflect Central Sensitization · 2026 · Related
  3. Oral bioavailability of curcumin: problems and advancements · Weidong Liu · 2016 · 568 citations · Cited by this paper
  4. Long Term Anticoagulation for Venous Thromboembolism in Sickle Cell Disease: A Systematic Review (1995–December 2025) · 2026 · Related
  5. Primary role for adherent leukocytes in sickle cell vascular occlusion: A new paradigm · Aslıhan Turhan · 2002 · 483 citations · Cited by this paper
  6. Public Health Awareness of Sickle Cell Anemia: A Qualitative Descriptive Study among Educated Young Adults in India · 2026 · Related
  7. Neutrophils, platelets, and inflammatory pathways at the nexus of sickle cell disease pathophysiology · Dachuan Zhang · 2016 · 420 citations · Cited by this paper
  8. Using Electronic-Medical Records to Facilitate Transition From Pediatric to Adult Hematology for Sickle Cell Disease · 2026 · Related
  9. Inflammation in sickle cell disease · Nicola Conran · 2018 · 296 citations · Cited by this paper
  10. Warrior Intelligence: A Community-Led Navigation Infrastructure for Real-Time Sickle Cell Crisis Data and Clinical Blind Spot Detection · 2026 · Related
  11. Natural History of Blood Pressure in Sickle Cell Disease: Risks for Stroke and Death Associated with Relative Hypertension in Sickle Cell Anemia · Charles H. Pegelow · 1997 · 271 citations · Cited by this paper
  12. Patient-Specific Modeling Reveals Stroke-Related Cerebral Hemodynamic Changes in Adults With Sickle Cell Disease · 2026 · Related
  13. Endothelial nitric oxide synthase in red blood cells: Key to a new erythrocrine function? · Miriam Margherita Cortese-Krott · 2014 · 185 citations · Cited by this paper
  14. Dietary Antioxidant Intake and Associations with Self-Reported Pain Among Adults Living with Sickle Cell Disease in the U.S · 2026 · Related
  15. Interplay between coagulation and vascular inflammation in sickle cell disease · Erica Sparkenbaugh · 2013 · 170 citations · Cited by this paper
  16. From Sidelines to Systems: An Interprofessional Model for Supporting Athletes with Sickle Cell Disease · 2026 · Related
  17. Curcumin improves endothelial dysfunction and vascular remodeling in 2K-1C hypertensive rats by raising nitric oxide availability and reducing oxidative stress · Orachorn Boonla · 2014 · 120 citations · Cited by this paper
  18. Association between Newborn Sickle Cell Disease and Low Birth Weight Among Full-term Births: A Population-Based Study in the State of Virginia (2014- 2023) · 2026 · Related
  19. Rat spinotrapezius muscle preparation for microscopic observation of the terminal vascular bed · Sarah D. Gray · 1973 · 119 citations · Cited by this paper
  20. Accelerating access to gene therapy: Lessons from commercial implementation in sickle cell disease and transfusion-dependent thalassemia · 2026 · Related
  21. Sickle Red Cell Microrheology and Sickle Blood Rheology · Samir K. Ballas · 2004 · 116 citations · Cited by this paper
  22. Sickle Cell Disease: Role of Oxidative Stress and Antioxidant Therapy · Rosa Vona · 2021 · 105 citations · Cited by this paper
  23. The Role of RBC Oxidative Stress in Sickle Cell Disease: From the Molecular Basis to Pathologic Implications · Qinhong Wang · 2021 · 92 citations · Cited by this paper
  24. Analysis of phosphorescence in heterogeneous systems using distributions of quencher concentration · Aleksander Sergeevich Golub · 1997 · 86 citations · Cited by this paper
  25. Time-dependent changes in the density and hemoglobin F content of biotin-labeled sickle cells. · R S Franco · 1998 · 81 citations · Cited by this paper
  26. Probing vasoocclusion phenomena in sickle cell anemia via mesoscopic simulations · Huan Lei · 2013 · 78 citations · Cited by this paper
  27. Thermostatic animal platform for intravital microscopy of thin tissues · Aleksander Sergeevich Golub · 2003 · 47 citations · Cited by this paper
  28. Vascular complications of sickle cell disease · Ashar Usmani · 2018 · 38 citations · Cited by this paper
  29. Effects of a hemoglobin-based oxygen carrier (HBOC-201) and derivatives with altered oxygen affinity and viscosity on systemic and microcirculatory variables in a top-load rat model · Bjorn Kyungsuck Song · 2014 · 31 citations · Cited by this paper
  30. Sickle cell disease as a vascular disorder · Solomon Fiifi Ofori-Acquah · 2020 · 28 citations · Cited by this paper
  31. Simultaneous sampling of tissue oxygenation and oxygen consumption in skeletal muscle · William H. Nugent · 2015 · 27 citations · Cited by this paper
  32. Microvascular and Systemic Impact of Resuscitation with PEGylated Carboxyhemoglobin-Based Oxygen Carrier or Hetastarch in a Rat Model of Transient Hemorrhagic Shock · William H. Nugent · 2019 · 21 citations · Cited by this paper
  33. Regulatory effects of curcumin on nitric oxide signaling in the cardiovascular system · Sajad Abolfazli · 2023 · 17 citations · Cited by this paper
  34. Novel transdermal curcumin therapeutic preserves endothelial barrier function in a high-dose LPS rat model · William H. Nugent · 2023 · 13 citations · Cited by this paper
  35. Reduced blood pressure in sickle cell disease is associated with decreased angiotensin converting enzyme (ACE) activity and is not modulated by ACE inhibition · Pâmela L. Brito · 2022 · 12 citations · Cited by this paper
  36. Faster Sickling Kinetics and Sickle Cell Shape Evolution during Repeated Deoxygenation and Oxygenation Cycles · Enming Du · 2018 · 10 citations · Cited by this paper
  37. Microvascular and systemic responses to novel PEGylated carboxyhaemoglobin-based oxygen carrier in a rat model of vaso-occlusive crisis · William H. Nugent · 2019 · 9 citations · Cited by this paper
  38. Inflammatory pathways and anti‐inflammatory therapies in sickle cell disease · Karina Tozatto‐Maio · 2024 · 9 citations · Cited by this paper
  39. Targeting sickle cell pathobiology and pain with novel transdermal curcumin · Yugal Goel · 2025 · 9 citations · Cited by this paper

Source: OpenAlex (CC0)