Research map: From inflammaging to steroid resistance: reframing the pathogenesis of neutrophilic asthma

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Papers in this map

  1. Role for NLRP3 Inflammasome–mediated, IL-1β–Dependent Responses in Severe, Steroid-Resistant Asthma · Richard Kim · 2017 · 448 citations · Cited by this paper
  2. An immunodominance perspective on a paradoxical phenomenon: discovery and modeling of ragweed and tree sensitization as negative predictors for high mugwort IgE reactivity · 2026 · Related
  3. Senolytics dasatinib and quercetin in idiopathic pulmonary fibrosis: results of a phase I, single-blind, single-center, randomized, placebo-controlled pilot trial on feasibility and tolerability · Anoop M. Nambiar · 2023 · 286 citations · Cited by this paper
  4. Challenges of using the Occupational Asthma-specific job exposure matrix to assess occupational exposure and hand eczema · 2026 · Related
  5. Tight junction, mucin, and inflammasome‐related molecules are differentially expressed in eosinophilic, mixed, and neutrophilic experimental asthma in mice · Hern‐Tze Tina Tan · 2018 · 171 citations · Cited by this paper
  6. The potential of targeted IL-4 therapy for the comorbidity of atopic dermatitis and attention-deficit/hyperactivity disorder in children via the skin-brain axis · 2026 · Related
  7. Neutrophils in asthma: the good, the bad and the bacteria · Helena A Crisford · 2021 · 125 citations · Cited by this paper
  8. Allergic diseases in early childhood and their association with migraine: a large-scale retrospective study · 2026 · Related
  9. Orally-active, clinically-translatable senolytics restore α-Klotho in mice and humans · Yi Zhun Zhu · 2022 · 96 citations · Cited by this paper
  10. IgE levels correlate with FcεRI expression on circulatory basophils but not with their activation response in patients with Hymenoptera anaphylaxis · 2026 · Related
  11. Targeting lymphoid-derived IL-17 signaling to delay skin aging · Paloma Solá · 2023 · 86 citations · Cited by this paper
  12. Cpg boosts peptide-based oral immunotherapy in mice with peanut allergy · 2026 · Related
  13. IL-17–CXC Chemokine Receptor 2 Axis Facilitates Breast Cancer Progression by Up-Regulating Neutrophil Recruitment · Lingyun Wu · 2019 · 77 citations · Cited by this paper
  14. Homeopathic medication for seasonal allergic rhinitis—a randomised placebo-controlled trial · 2026 · Related
  15. Neutrophils restrain sepsis associated coagulopathy via extracellular vesicles carrying superoxide dismutase 2 in a murine model of lipopolysaccharide induced sepsis · Wenjie Bao · 2022 · 75 citations · Cited by this paper
  16. The forgotten billion: bridging the global allergy care chasm through scalable, equity-driven strategies · 2026 · Related
  17. Effect of aging on sputum inflammation and asthma control · Paula Jane Busse · 2016 · 72 citations · Cited by this paper
  18. Bridging innovation and risk: the missing role of validated risk-stratification in IgE-mediated food allergy management · 2026 · Related
  19. Immunosenescence, Inflammaging, and Lung Senescence in Asthma in the Elderly · Tomoyuki Soma · 2022 · 69 citations · Cited by this paper
  20. Mechanisms regulating neutrophil responses in immunity, allergy, and autoimmunity · Alaz Özcan · 2022 · 52 citations · Cited by this paper
  21. Role of the NLRP3 inflammasome in asthma: Relationship with neutrophilic inflammation, obesity, and therapeutic options · Evan J. Williams · 2021 · 51 citations · Cited by this paper
  22. Neutrophil extracellular trap production and CCL4L2 expression influence corticosteroid response in asthma · Ching‐Hui Tsai · 2023 · 47 citations · Cited by this paper
  23. An anti-complement homogeneous polysaccharide from Houttuynia cordata ameliorates acute pneumonia with H1N1 and MRSA coinfection through rectifying Treg/Th17 imbalance in the gut–lung axis and NLRP3 inflammasome activation · Xinxing Li · 2025 · 31 citations · Cited by this paper
  24. Cellular senescence in chronic obstructive pulmonary disease: Molecular mechanisms and therapeutic interventions · Sapana Subedi · 2025 · 31 citations · Cited by this paper
  25. Aging-induced immune microenvironment remodeling fosters melanoma in male mice via γδ17-Neutrophil-CD8 axis · Runping Duan · 2024 · 29 citations · Cited by this paper
  26. Diagnosis and Treatment Options for T2-Low Asthma · Dennis Thomas · 2025 · 26 citations · Cited by this paper
  27. Glucocorticoids promote CCL20 expression in keratinocytes · Lanqi Wang · 2021 · 24 citations · Cited by this paper
  28. LECs regulate neutrophil clearance through IL-17RC/CMTM4/NF-κB axis at sites of inflammation or infection · Qiaoqi Ni · 2024 · 24 citations · Cited by this paper
  29. Involvement of IL-17 A/IL-17 Receptor A with Neutrophil Recruitment and the Severity of Coronary Arteritis in Kawasaki Disease · I-Chun Lin · 2024 · 23 citations · Cited by this paper
  30. House dust mite‐induced Akt‐ERK1 / 2‐C / EBP beta pathway triggers CCL20 ‐mediated inflammation and epithelial–mesenchymal transition for airway remodeling · Shin‐Young Park · 2022 · 18 citations · Cited by this paper
  31. Characterization and inhibition of inflammasome responses in severe and non-severe asthma · Jay Christopher Horvat · 2023 · 15 citations · Cited by this paper
  32. Potential Role of Inflammasomes in Aging · Gilyoung Lee · 2025 · 15 citations · Cited by this paper
  33. Senotherapy for chronic lung disease · Peter John Barnes · 2025 · 14 citations · Cited by this paper
  34. The oncogenic kinase TOPK upregulates in psoriatic keratinocytes and contributes to psoriasis progression by regulating neutrophils infiltration · Fanfan Zeng · 2024 · 13 citations · Cited by this paper
  35. Unraveling CCL20's role by regulating Th17 cell chemotaxis in experimental autoimmune prostatitis · Cheng Zhang · 2024 · 12 citations · Cited by this paper
  36. Intermittent hypoxia aggravates asthma inflammation via NLRP3/IL-1β-dependent pyroptosis mediated by HIF-1α signalling pathway · Ling Zhou · 2025 · 12 citations · Cited by this paper
  37. Modified Bushen Yiqi Formula mitigates pulmonary inflammation and airway remodeling by inhibiting neutrophils chemotaxis and IL17 signaling pathway in rats with COPD · Qing Kong · 2023 · 11 citations · Cited by this paper
  38. Epigenetic age acceleration and allergic diseases: a bidirectional two-sample Mendelian randomization study · Junfang Sun · 2025 · 6 citations · Cited by this paper
  39. Chronic lung diseases (Asthma and COPD) among middle-aged and older populations in India: social, individual, and household determinants and their associations with geriatric syndromes · Aditi Chakraborty · 2025 · 5 citations · Cited by this paper

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