Hepatocyte MLKL drives obesity-driven hepatocellular carcinoma progression via mitochondrial dysfunction independent of necroptosis in MASLD

Hepatology · Published 2026-08-04 · DOI 10.1097/hep.0000000000001830

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Authors (22)

Phoebe Ohene-Marfo, Sabira Mohammed, Chao Jiang, Shylesh Bhaskaran, Kara Kneuper, Satoshi Matsuzaki, Bo Hagy, Randal J. May, Constantin Georgescu, Megan John, Julianne N. Hoang, Kevin Pham, Albert Tran, Chinthalapally V. Rao, Tae Gyu Oh, Michael Kinter, Willard M. Freeman, Courtney Houchen, Surendra Shukla, Kenneth Humphries, Jonathan D. Wren, Sathyaseelan S. Deepa

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Publication details

Year

2026

Citation

Ohene-Marfo, P., Mohammed, S., Jiang, C., et al. (2026). Hepatocyte MLKL drives obesity-driven hepatocellular carcinoma progression via mitochondrial dysfunction independent of necroptosis in MASLD. Hepatology. https://doi.org/10.1097/hep.0000000000001830

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