Dual Modulation of Prostaglandin E2 Receptors EP3 and EP4 Protects β-Cell Mass in a Model of Aggressive Autoimmune Inflammation

Diabetes · Published 2026-07-31 · DOI 10.2337/db25-1007

Free full text

Authors (15)

Juliann B. Burkett, Jennifer Fuhr, Alexander C. Falk, Prasanna Dadi, Alexa N. Del Bene, Audrey Lucerne, Dudley McNitt, Landon M. Clark, Micaela Maxwell, Victoria Gaeth, Kaelyn Allen, David Jacobson, Daniel J. Moore, Christopher S. Wilson, Maureen Gannon

Abstract

PubPorta does not have an abstract for this article yet.

Read the article at the publisher →

Publication details

Year

2026

Citation

Burkett, J., Fuhr, J., Falk, A., et al. (2026). Dual Modulation of Prostaglandin E2 Receptors EP3 and EP4 Protects β-Cell Mass in a Model of Aggressive Autoimmune Inflammation. Diabetes. https://doi.org/10.2337/db25-1007

Related articles

• GIP Acutely Blunts Insulin- and GLP-1–Induced Muscle Microvascular Perfusion · Diabetes · 2026 · Same journal
• 1314-OR: Allogeneic Islets Are Rejected by Diabetic NOD Mice while Allogeneic Neo-Islets, 3D Organoids of Islet and Mesenchymal Stromal Cells, Durably Cure Their Type 1 Diabetes without Antirejection Drugs: Mechanisms · Diabetes · 2026 · Same journal
• 1295-OR: Safety and Efficacy Study of a Needle-Free Intradermal Glucose Sensor with Activity and Sleep Tracking · Diabetes · 2026 · Same journal
• 1278-OR: IGFBP7 Blockade Protects from Diabetic Cardiomyopathy · Diabetes · 2026 · Same journal
• 1289-OR: Effect of Different Treatment Durations of Sodium–Glucose Cotransporter 2 Inhibitor on Cardiovascular Outcomes in Patients with Type 2 Diabetes: A Target Trial Emulation Study · Diabetes · 2026 · Same journal
• 1342-OR: CGM Data Provides Weekly Insulin Efsitora Dose Guidance Equivalent to the Current Standard of FBG and Hypoglycemia Events for T2D Insulin Naïve Adults: A Retrospective Analysis · Diabetes · 2026 · Same journal
• The Mechanism of TNF-α Combined With High Glucose in Regulating Calnexin Aggravates Endoplasmic Reticulum Stress in Endothelial Cell Injury of Diabetic Retinopathy · Diabetes · 2026 · Same journal
• Adipose Tissue Overexpression of Nicotinamide Phosphoribosyltransferase Prevents Metabolic Dysfunction in Obese Mice via Extracellular Vesicles · Diabetes · 2026 · Same journal
• 1316-OR: Prevention of Cellular Senescence and EMT Enables Expansion of Human Pluripotent Stem Cell–Derived Pancreatic Endoderm Cells · Diabetes · 2026 · Same journal
• Effects of Pharmacological GIP Infusion on Insulin, Glucagon, and Cardiovascular Responses During Hyperglycemia in Type 2 Diabetes · Diabetes · 2026 · Same journal