Routes to colorectal cancer in Lynch syndrome: a decade of molecular and clinical insights converging on Schrödinger’s cat

Familial Cancer · Published 2026-08-04 · DOI 10.1007/s10689-026-00593-w

Free full text

Authors (5)

Aysel Ahadova, Fatima Fayyaz, Leon Marin Grez, Hendrik Bläker, Matthias Kloor

Abstract

PubPorta does not have an abstract for this article yet.

Read the article at the publisher →

Publication details

Year

2026

Citation

Ahadova, A., Fayyaz, F., Grez, L., et al. (2026). Routes to colorectal cancer in Lynch syndrome: a decade of molecular and clinical insights converging on Schrödinger’s cat. Familial Cancer. https://doi.org/10.1007/s10689-026-00593-w

Related articles

• A computational model for investigating the evolution of colonic crypts during Lynch syndrome carcinogenesis · Computational and Systems Oncology · 2021 · Cites or is cited by this article
• Incidences of colorectal adenomas and cancers under colonoscopy surveillance suggest an accelerated “Big Bang” pathway to CRC in three of the four Lynch syndromes · Hereditary Cancer in Clinical Practice · 2024 · Cites or is cited by this article
• Colonoscopy findings and polyp pathology in CHEK2 carriers: a single center experience · Familial Cancer · 2026 · Same journal
• Familial risks in prostate cancer between brothers and half-brothers as clues to germline genetic and environmental causes · Familial Cancer · 2026 · Same journal
• Attenuated Li–Fraumeni syndrome with TP53 p.R181H in a Japanese patient with metastatic rectal adenocarcinoma: a case report · Familial Cancer · 2026 · Same journal
• Patient-derived outcome assessment of knowledge, communication, and management in those diagnosed with BAP1-tumor predisposition syndrome · Familial Cancer · 2026 · Same journal
• Breast cancer phenotypes in carriers of pathogenic POT1 variants · Familial Cancer · 2026 · Same journal
• Homozygous TP53 alterations: a case of a biallelic splice variant and a brief review of the literature · Familial Cancer · 2026 · Same journal
• Genotypic and phenotypic characteristics of germline TP53 variant carriers: experience from two cancer genetic counseling units · Familial Cancer · 2026 · Same journal
• When screentime fails: initiative to improve completion of hereditary cancer genetic testing after telemedicine counseling · Familial Cancer · 2026 · Same journal