RADX protects against intestinal inflammation by restraining IFI16-mediated innate immunity

EMBO Molecular Medicine · Published 2026-07-24 · DOI 10.1038/s44321-026-00494-6

Free full text

Authors (27)

Huifang Xian, Wanming Huang, Zhanghua Chen, Lili Li, Liya Xiong, Jianheng Zhu, Haolan Jin, Xiaotian Li, Lizhi Song, Peiyu Chen, Lu Ren, Wei Wang, Rongli Fang, Xixi Chen, Wen Lei, Dengfeng Zhang, Weiliang Liao, Yuxin Huang, Andrew M Lew, Jun Cui, Sitang Gong, Jun Huang, Jaime S Rosa Duque, Min Zhi, Lanlan Geng, Wenhao Zhou, Yuxia Zhang

Abstract

PubPorta does not have an abstract for this article yet.

Read the article at the publisher →

Publication details

Year

2026

Citation

Xian, H., Huang, W., Chen, Z., et al. (2026). RADX protects against intestinal inflammation by restraining IFI16-mediated innate immunity. EMBO Molecular Medicine. https://doi.org/10.1038/s44321-026-00494-6

Related articles

• From Genes to Gut: Understanding Diagnosis and Treatment in Very Early Onset Inflammatory Bowel Disease · Pediatric Annals · 2025 · Cites or is cited by this article
• Mitochondrial activity promotes neutrophil degranulation and endothelial dysfunction in systemic infections · EMBO Molecular Medicine · 2026 · Same journal
• Impaired gephyrin G-domain trimerization and phase separation in a patient with developmental epileptic encephalopathy · EMBO Molecular Medicine · 2026 · Same journal
• Neoantigens and shared MICB α3 antigen dual-targeted vaccine generates potent antitumor immunity · EMBO Molecular Medicine · 2026 · Same journal
• Patient-derived resources for decoding and targeting brain metastases ecosystems · EMBO Molecular Medicine · 2026 · Same journal
• Loss of mitochondrial DNA helicase in retinal macroglia drives neovascular retinopathy · EMBO Molecular Medicine · 2026 · Same journal
• CCDC174 deficiency impaired human fertility by affecting the alternative splicing of maternal mRNAs · EMBO Molecular Medicine · 2026 · Same journal
• β-hydroxybutyrate restores social deficits by suppressing HDAC9 in the ACC of Shank3B-deficient mice · EMBO Molecular Medicine · 2026 · Same journal
• Targeted enzymatic therapy for coeliac disease · EMBO Molecular Medicine · 2026 · Same journal
• Experimental models for intestinal host-microbe interactions · EMBO Molecular Medicine · 2026 · Same journal