Beyond necroptosis: structural determinants, context-dependent non-canonical functions, and precision therapeutic targeting of RIPK3

Biochemical Pharmacology · Published 2026-08-01 · DOI 10.1016/j.bcp.2026.118310

Authors (9)

Yuntian Shen, Haiyan Jiang, Jie Wang, Yanan Ji, Xinlei Yao, Jiacheng Sun, Meiyuan Li, Hua Liu, Hualin Sun

Abstract

PubPorta does not have an abstract for this article yet.

Read the article at the publisher →

Publication details

Year

2026

Citation

Shen, Y., Jiang, H., Wang, J., et al. (2026). Beyond necroptosis: structural determinants, context-dependent non-canonical functions, and precision therapeutic targeting of RIPK3. Biochemical Pharmacology. https://doi.org/10.1016/j.bcp.2026.118310

Related articles

• RIPK3 Inhibition Mitigates Denervated Muscle Atrophy via NOX4‐Mediated Mitochondrial Restoration and Inflammation Suppression · Journal of Cachexia, Sarcopenia and Muscle · 2026 · Cites or is cited by this article
• Targeting RIPK1 for the treatment of depression: From neuroinflammation to synaptic plasticity · Biochemical Pharmacology · 2026 · Same journal
• BiP-engaging xanthones from the mangosteen (Garcinia mangostana) induce androgen receptor degradation in prostate cancer cells · Biochemical Pharmacology · 2026 · Same journal
• Advanced therapy medicinal products for local treatment using new delivery methods · Biochemical Pharmacology · 2026 · Same journal
• Genetic polymorphisms of drug-metabolizing cytochromes P450 and flavin-containing monooxygenases in dogs and pigs inform the prediction of drug metabolism and toxicity in humans and other animal species · Biochemical Pharmacology · 2026 · Same journal
• CerS2/ceramide C24:1/ROCK2 signaling-mediated angiogenesis protects against ischemic brain injury in mice · Biochemical Pharmacology · 2026 · Same journal
• Core genes drive treatment resistance in triple-negative breast cancer: characteristics, mechanisms, intervention strategies · Biochemical Pharmacology · 2026 · Same journal
• HDAC1-mediated PKM2 delactylation modification regulates CIRP-induced angiogenesis in rheumatoid arthritis · Biochemical Pharmacology · 2026 · Same journal
• Orforglipron alleviates aortic aneurysm and dissection via inhibiting WNT5A noncanonical signaling · Biochemical Pharmacology · 2026 · Same journal
• Glycoprotein nonmetastatic B as a pharmacological target in cancer: structural mechanisms, druggability, and therapeutic translation · Biochemical Pharmacology · 2026 · Same journal