Treatment of Shiga toxin–producing E. coli infection by CRISPR-Cas–targeted cleavage of the Shiga toxin gene in animal models

Science Translational Medicine · Published 2026-05-27 · DOI 10.1126/scitranslmed.adw8114

Authors (29)

Matthieu Galtier, Antonina Krawczyk, Fabien J. Fuche, Loïc H. Charpenay, Igor Stzepourginski, Simone Pignotti, Marion Arraou, Rémi Terrasse, Andreas K. Brödel, Chloé Poquet, Gautier Prevot, Dalila Spadoni, Benjamin Buhot, Kristin Muench, Jan Havránek, Pablo Cárdenas Ramírez, Marie Rouquette, Antoine Decrulle, Olivier Kerbarh, Erica Lieberman, Camila Bramorski, Aurélie Grienenberger, Edith M. Hessel, Giuseppina Salzano, Daniel J. Garry, Aymeric Leveau, Xavier Duportet, David Bikard, Jesus Fernandez-Rodriguez

Abstract

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Publication details

Year

2026

Citation

Galtier, M., Krawczyk, A., Fuche, F., et al. (2026). Treatment of Shiga toxin–producing E. coli infection by CRISPR-Cas–targeted cleavage of the Shiga toxin gene in animal models. Science Translational Medicine. https://doi.org/10.1126/scitranslmed.adw8114

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