Clinical and Laboratory Characteristics of Elderly Patients with Type 2 Diabetes Mellitus in Samara, Russia: A Registry-Based Study

Russian Open Medical Journal · Published 2025-09-30 · DOI 10.15275/rusomj.2025.0314

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Abstract

Relevance — A comprehensive analysis of standard inpatient monitoring indicators for Diabetes Mellitus (DM) accessible to physicians during routine outpatient visits provides valuable insights within the context of a registry-based study. This approach is scientifically significant as it enables the identification of patterns in the interplay between comorbidities and vascular complications of diabetes in elderly patients, along with key factors driving their progression. Aim — To conduct a comprehensive epidemiological assessment of the clinical and metabolic profiles of elderly outpatients with Type 2 Diabetes Mellitus (T2DM) in Samara, based on a registry study. Material and Methods — This retrospective study analyzed data from 837 outpatient consultation records of 484 elderly patients with T2DM, aged 60 to 74.9 years. The data were stored in a local registry utilizing specialized digital tools and a formalized protocol. Epidemiological indicators, parameters of therapeutic control of diabetes, frequency of target achievement, and drug therapy regimens were evaluated. Results and Conclusion — The study revealed a high prevalence of cardiovascular complications in Diabetes Mellitus (DM), closely linked to the frequency of atherogenic comorbidities such as hypertension, obesity, and dyslipidemia. These conditions are driven by pronounced insulin resistance and metabolic syndrome, which are characteristic of the elderly population. The achievement of therapeutic control targets — glycated hemoglobin (HbA1c), blood glucose levels, and systolic blood pressure (SBP) – was generally unsatisfactory. Additionally, although drug therapy was frequently prescribed, it often failed to adequately address the pronounced manifestations of concomitant metabolic syndrome. The findings support optimizing guidelines for outpatient monitoring of elderly patients with T2DM through a multidisciplinary team approach, mandating the involvement of a cardiology specialist.

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Publication details

Year
2025

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