PARP7 enhances doxorubicin-induced cardiomyocyte ferroptosis and cardiotoxicity by ADP-ribosylation-dependent suppression of GPX4 activity

Translational Research · Published 2026-08-02 · DOI 10.1016/j.trsl.2026.07.016

Authors (10)

Yiting Lyu, Lintao Wang, Xiaowen Shi, Yang Li, Ke Xu, Jian Sheng, Xin Zhong, Huihui Xie, Jiajun Xu, Jibo Han

Abstract

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Publication details

Year

2026

Citation

Lyu, Y., Wang, L., Shi, X., et al. (2026). PARP7 enhances doxorubicin-induced cardiomyocyte ferroptosis and cardiotoxicity by ADP-ribosylation-dependent suppression of GPX4 activity. Translational Research. https://doi.org/10.1016/j.trsl.2026.07.016

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