Circadian rhythm disruption induces cardiac hypertrophy via promoting the mtDNA release-activated cGAS-STING pathway

Biochemical Pharmacology · Published 2026-08-01 · DOI 10.1016/j.bcp.2026.118309

Free full text

Authors (13)

Zizhang Ouyang, Runqi Luo, Jingxuan Li, Qiuyan Huang, Ziying Chen, Daofeng Cai, Sihua Zhu, Jun Gao, Zhanfang Kang, Peibin Lin, Guanfeng Liang, Ning Hou, Xiaoping Liu

Abstract

PubPorta does not have an abstract for this article yet.

Read the article at the publisher →

Publication details

Year

2026

Citation

Ouyang, Z., Luo, R., Li, J., et al. (2026). Circadian rhythm disruption induces cardiac hypertrophy via promoting the mtDNA release-activated cGAS-STING pathway. Biochemical Pharmacology. https://doi.org/10.1016/j.bcp.2026.118309

Related articles

• Renal denervation attenuates cardiac dysfunction in HFpEF by inhibiting the ATP-P2X7-NLRP3 inflammasome axis · Basic Research in Cardiology · 2025 · Cites or is cited by this article
• Targeting RIPK1 for the treatment of depression: From neuroinflammation to synaptic plasticity · Biochemical Pharmacology · 2026 · Same journal
• BiP-engaging xanthones from the mangosteen (Garcinia mangostana) induce androgen receptor degradation in prostate cancer cells · Biochemical Pharmacology · 2026 · Same journal
• Advanced therapy medicinal products for local treatment using new delivery methods · Biochemical Pharmacology · 2026 · Same journal
• Genetic polymorphisms of drug-metabolizing cytochromes P450 and flavin-containing monooxygenases in dogs and pigs inform the prediction of drug metabolism and toxicity in humans and other animal species · Biochemical Pharmacology · 2026 · Same journal
• CerS2/ceramide C24:1/ROCK2 signaling-mediated angiogenesis protects against ischemic brain injury in mice · Biochemical Pharmacology · 2026 · Same journal
• Core genes drive treatment resistance in triple-negative breast cancer: characteristics, mechanisms, intervention strategies · Biochemical Pharmacology · 2026 · Same journal
• HDAC1-mediated PKM2 delactylation modification regulates CIRP-induced angiogenesis in rheumatoid arthritis · Biochemical Pharmacology · 2026 · Same journal
• Orforglipron alleviates aortic aneurysm and dissection via inhibiting WNT5A noncanonical signaling · Biochemical Pharmacology · 2026 · Same journal
• Glycoprotein nonmetastatic B as a pharmacological target in cancer: structural mechanisms, druggability, and therapeutic translation · Biochemical Pharmacology · 2026 · Same journal