Tumour cell density quantified by artificial intelligence is associated with differential benefit from irinotecan-based chemo-radiotherapy in locally advanced rectal cancer: a post-hoc study of the phase 3 ARISTOTLE trial

EBioMedicine · Published 2026-07-01 · DOI 10.1016/j.ebiom.2026.106397

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Authors (11)

Zhuoyan Shen, Douglas Brand, Mikaël Simard, Nicholas P. West, Andre Lopes, Rubina Begum, Ying Zhang, Gary Royle, David Sebag-Montefiore, Charles-Antoine Collins Fekete, Maria A. Hawkins

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Year

2026

Citation

Shen, Z., Brand, D., Simard, M., et al. (2026). Tumour cell density quantified by artificial intelligence is associated with differential benefit from irinotecan-based chemo-radiotherapy in locally advanced rectal cancer: a post-hoc study of the phase 3 ARISTOTLE trial. EBioMedicine. https://doi.org/10.1016/j.ebiom.2026.106397

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