Medical Mycology Case Reports · Published 2026-03-17 · DOI 10.1016/j.mmcr.2026.100781
Fungal infective endocarditis is a rare but highly morbid condition commonly caused by Candida species. Candida parapsilosis is an uncommon cause of native valve endocarditis and is increasingly associated with healthcare exposure. We report a 50-year-old woman with persistent Candida parapsilosis candidemia complicated by large native aortic valve vegetations and acute limb ischemia from arterial embolization, requiring surgical valve replacement and prolonged antifungal therapy.
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