Research map: Clinical trials in late-stage Parkinson's disease

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Papers in this map

  1. The Emerging Evidence of the Parkinson Pandemic · Earl Ray Dorsey · 2018 · 2061 citations · Cited by this paper
  2. Integrating a biopsychosocial perspective: WHODAS 2.0 enhances functioning assessment in Parkinson's disease · 2026 · Related
  3. International Parkinson and movement disorder society evidence‐based medicine review: Update on treatments for the motor symptoms of Parkinson's disease · Susan Helen Fox · 2018 · 1011 citations · Cited by this paper
  4. A case of monotherapy with intracerebroventricular anaerobic dopamine allows complete control of Parkinson's disease symptoms · 2025 · Related
  5. Summary of the recommendations of the EFNS / MDS ‐ ES review on therapeutic management of P arkinson's disease · Joaquim José Ferreira · 2012 · 345 citations · Cited by this paper
  6. A review of FDG-PET biomarker analysis methods in Parkinson's disease · 2026 · Related
  7. Developing consensus among movement disorder specialists on clinical indicators for identification and management of advanced Parkinson’s disease: a multi-country Delphi-panel approach · Angelo Antonini · 2018 · 281 citations · Cited by this paper
  8. Effects of deep brain stimulation on functional autonomy and quality of life in Parkinson's disease: A systematic review and meta-analysis · 2026 · Related
  9. Late-stage Parkinson disease · Miguel M Coelho · 2012 · 253 citations · Cited by this paper
  10. Association between age at Parkinson's disease onset and divorce: An exploratory analysis from the fox insight cohort · 2026 · Related
  11. Patterns of levodopa response in Parkinson's disease: a clinico-pathological study · Peter A. Kempster · 2007 · 191 citations · Cited by this paper
  12. Continuous apomorphine infusion modulates cortical hyperexcitability and abnormal plasticity in Parkinson's disease · 2026 · Related
  13. European Academy of Neurology/Movement Disorder Society‐European Section Guideline on the Treatment of Parkinson's Disease: I. Invasive Therapies · Günther Deuschl · 2022 · 190 citations · Cited by this paper
  14. Rethinking the concept of disease modification in an evolving Parkinson's disease treatment landscape · 2026 · Related
  15. Overview on wearable sensors for the management of Parkinson’s disease · Caroline Moreau · 2023 · 147 citations · Cited by this paper
  16. Cognition endpoints for Parkinson's disease: A roadmap for developing patient-focused assessment tools to accelerate drug development · 2026 · Related
  17. Late-stage Parkinson’s disease: the Barcelona and Lisbon cohort · Miguel M Coelho · 2010 · 122 citations · Cited by this paper
  18. Gut microbiome dysbiosis, short-chain fatty acid depletion and implications for neuroinflammation in atypical parkinsonian syndromes – a systematic review of patient cohorts · 2026 · Related
  19. Do patients with late-stage Parkinson's disease still respond to levodopa? · Margherita Fabbri · 2016 · 78 citations · Cited by this paper
  20. Aligning incentives for open science in biomedical research: Navigating funder and institutional perspectives · 2025 · Related
  21. Update on Treatments for Parkinson's Disease Motor Fluctuations – An International Parkinson and Movement Disorder Society Evidence‐Based Medicine Review · Rob M. A. de Bie · 2025 · 69 citations · Cited by this paper
  22. Dysphagia predicts poor outcome in late-stage Parkinson's disease · Margherita Fabbri · 2019 · 67 citations · Cited by this paper
  23. The late stage of Parkinson's –results of a large multinational study on motor and non-motor complications · Anette E. Schrag · 2020 · 51 citations · Cited by this paper
  24. Levodopa Effect and Motor Function in Late Stage Parkinson’s Disease · Kristina Rosqvist · 2018 · 41 citations · Cited by this paper
  25. Caregiver Burden in Late-Stage Parkinsonism and Its Associations · Stefania Kalampokini · 2020 · 41 citations · Cited by this paper
  26. Challenges and Perspectives in the Management of Late-Stage Parkinson’s Disease · Margherita Fabbri · 2020 · 38 citations · Cited by this paper
  27. Factors Associated with Health‐Related Quality of Life in Late‐Stage Parkinson's Disease · Kristina Rosqvist · 2021 · 35 citations · Cited by this paper
  28. Reduction of Antihypertensive Treatment in Nursing Home Residents · Athanase Bénétos · 2025 · 32 citations · Cited by this paper
  29. Acute response of non-motor symptoms to subthalamic deep brain stimulation in Parkinson's disease · Margherita Fabbri · 2017 · 28 citations · Cited by this paper
  30. Proactive and Integrated Management and Empowerment in Parkinson’s Disease protocol for a randomised controlled trial (PRIME-UK) to evaluate a new model of care · Fiona E. Lithander · 2023 · 25 citations · Cited by this paper
  31. Outcome Measures for Disease-Modifying Trials in Parkinson’s Disease: Consensus Paper by the EJS ACT-PD Multi-Arm Multi-Stage Trial Initiative · Cristina Gonzalez‐Robles · 2023 · 22 citations · Cited by this paper
  32. Resource Utilization of Patients with Parkinson’s Disease in the Late Stages of the Disease in Germany: Data from the CLaSP Study · Christopher Kruse · 2021 · 20 citations · Cited by this paper
  33. Optimizing Treatment in Undertreated Late-Stage Parkinsonism: A Pragmatic Randomized Trial · Adrianus L.A.J. Hommel · 2020 · 16 citations · Cited by this paper
  34. Advantages and Challenges of Platform Trials for Disease Modifying Therapies in Parkinson's Disease · Margherita Fabbri · 2024 · 16 citations · Cited by this paper
  35. High frequency of psychosis in late-stage Parkinsońs disease · Inês Chendo · 2021 · 13 citations · Cited by this paper
  36. Care of Late‐Stage Parkinsonism: Resource Utilization of the Disease in Five European Countries · Christopher Kruse · 2024 · 12 citations · Cited by this paper
  37. Needs of patients with parkinsonism and their caregivers: a protocol for the PRIME-UK cross-sectional study · Emma Tenison · 2022 · 10 citations · Cited by this paper
  38. The Validity of Health-Related Quality of Life Instruments in Patients With Late-Stage Parkinson’s Disease · Mouhammed Ramadhan · 2022 · 8 citations · Cited by this paper
  39. Exclusion of older patients from randomized clinical trials in Parkinson’s disease · Danuta Kłosowska · 2024 · 7 citations · Cited by this paper

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