Research map: NT-A9, a new triazole, exhibits potent antifungal activity against Candida and Cryptococcus species through potent ergosterol biosynthesis inhibition

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  1. Clinical Practice Guideline for the Management of Candidiasis: 2016 Update by the Infectious Diseases Society of America · Peter G. Pappas · 2015 · 4223 citations · Cited by this paper
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  11. The Effect of Therapeutic Drug Monitoring on Safety and Efficacy of Voriconazole in Invasive Fungal Infections: A Randomized Controlled Trial · Wan Beom Park · 2012 · 399 citations · Cited by this paper
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  15. History of the development of antifungal azoles: A review on structures, SAR, and mechanism of action · Mohammad Shafiei · 2020 · 293 citations · Cited by this paper
  16. Recalculation of inhibitor concentration fold-changes for CMY-219: comments on a recent article about CMY-219 conferring resistance to ceftazidime-avibactam · 2026 · Related
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  18. NagX, a periplasmic β- N -acetylglucosaminidase, contributes to NagZ-independent β-lactamase expression in Stenotrophomonas maltophilia · 2026 · Related
  19. Rapid Induction of Multiple Resistance Mechanisms in Aspergillus fumigatus during Azole Therapy: a Case Study and Review of the Literature · Simone M. T. Camps · 2011 · 233 citations · Cited by this paper
  20. Candida auris and multidrug resistance: Defining the new normal · Shawn R. Lockhart · 2019 · 217 citations · Cited by this paper
  21. Structural Insights into Inhibition of Sterol 14α-Demethylase in the Human Pathogen Trypanosoma cruzi · Galina I. Lepesheva · 2010 · 147 citations · Cited by this paper
  22. Candida auris Infections · Michail S. Lionakis · 2024 · 122 citations · Cited by this paper
  23. Candidiasis: From cutaneous to systemic, new perspectives of potential targets and therapeutic strategies · Hui Lu · 2023 · 89 citations · Cited by this paper
  24. Clinical Practice Guideline for the Therapeutic Drug Monitoring of Voriconazole in Non-Asian and Asian Adult Patients: Consensus Review by the Japanese Society of Chemotherapy and the Japanese Society of Therapeutic Drug Monitoring · Yoshio Takesue · 2022 · 87 citations · Cited by this paper
  25. A comparative study of the post-antifungal effect (PAFE) of amphotericin B, triazoles and echinocandins on Aspergillus fumigatus and Candida albicans · Elias K. Manavathu · 2004 · 76 citations · Cited by this paper
  26. Candida auris: Epidemiology and Antifungal Strategy · Emily F. Eix · 2024 · 73 citations · Cited by this paper
  27. Understanding the mechanisms of resistance to azole antifungals in Candida species · Yunxiao Li · 2025 · 54 citations · Cited by this paper
  28. Pharmacology and clinical use of voriconazole · George R. Thompson · 2009 · 52 citations · Cited by this paper
  29. Design, synthesis, and in vitro evaluation of novel antifungal triazoles · Fei Xie · 2017 · 49 citations · Cited by this paper
  30. Toxic eburicol accumulation drives the antifungal activity of azoles against Aspergillus fumigatus · Hesham Elsaman · 2024 · 47 citations · Cited by this paper
  31. Understanding fluconazole tolerance in Candida albicans: implications for effective treatment of candidiasis and combating invasive fungal infections · Yanru Feng · 2023 · 39 citations · Cited by this paper
  32. Baicalein Acts against Candida albicans by Targeting Eno1 and Inhibiting Glycolysis · Liping Li · 2022 · 38 citations · Cited by this paper
  33. Myriocin enhances the antifungal activity of fluconazole by blocking the membrane localization of the efflux pump Cdr1 · Hongkang Wang · 2022 · 31 citations · Cited by this paper
  34. A Small Molecule Inhibitor of Erg251 Makes Fluconazole Fungicidal by Inhibiting the Synthesis of the 14α-Methylsterols · Hui Lu · 2022 · 30 citations · Cited by this paper
  35. The evolution of antifungal therapy: Traditional agents, current challenges and future perspectives · Cássia Milena de Souza · 2025 · 27 citations · Cited by this paper
  36. Differential Response of Candida Species Morphologies and Isolates to Fluconazole and Boric Acid · Ola E. Salama · 2022 · 25 citations · Cited by this paper
  37. The Microevolution of Antifungal Drug Resistance in Pathogenic Fungi · Kylie J. Boyce · 2023 · 24 citations · Cited by this paper
  38. Candidozyma auris (formerly Candida auris): resistant, long lasting, and everywhere · Jon Salmanton-Garcia · 2026 · 23 citations · Cited by this paper
  39. Mutant Prevention Concentration and Mutant Selection Window of Micafungin and Anidulafungin in Clinical Candida glabrata Isolates · María Ángeles Bordallo-Cardona · 2018 · 21 citations · Cited by this paper

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