Research map: Erectile dysfunction in aging men: evidence and insights related to antihypertensive and antidiabetic medications

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  1. Efficacy and safety of glucagon‐like peptide‐1 receptor agonists in type 2 diabetes: A systematic review and mixed‐treatment comparison analysis · Zin Zin Htike · 2016 · 419 citations · Cited by this paper
  2. Small RNA profile alterations as a potential mechanism for sperm quality improvement following varicocelectomy · 2026 · Related
  3. Interactions between erectile dysfunction, cardiovascular disease and cardiovascular drugs · Dimitrios G. Terentes-Printzios · 2021 · 161 citations · Cited by this paper
  4. Molecular mechanisms of erectile dysfunction in type 1 and type 2 diabetic rats: a multiomics approach · 2026 · Related
  5. Molecular Mechanisms of SGLT2 Inhibitor on Cardiorenal Protection · Yi‐Chou Hou · 2020 · 101 citations · Cited by this paper
  6. A novel hemizygous missense variant in the BEND2 gene is associated with nonobstructive azoospermia · 2026 · Related
  7. Antihypertensive Treatment and Sexual Dysfunction · Athanasios J. Manolis · 2012 · 92 citations · Cited by this paper
  8. Disease characteries, treatment patterns, and oncological outcomes of de novo metastatic hormone-sensitive prostate cancer: real-world experience from a multicenter Asian cohort · 2026 · Related
  9. ACE-Inhibitors in Hypertension: A Historical Perspective and Current Insights · Stacey Cutrell · 2023 · 87 citations · Cited by this paper
  10. Testicular sperm aspiration enhances fertilization rates in MMAF patients undergoing ICSI: a retrospective cohort study · 2026 · Related
  11. Individualized Beta-Blocker Treatment for High Blood Pressure Dictated by Medical Comorbidities: Indications Beyond the 2018 European Society of Cardiology/European Society of Hypertension Guidelines · Giuseppe Mancia · 2022 · 85 citations · Cited by this paper
  12. Dynamic changes of serum albumin-to-globulin ratio predict major adverse cardiovascular events in prostate cancer patients undergoing androgen deprivation therapy · 2026 · Related
  13. Erectile Dysfunction in a Sample of Sexually Active Young Adult Men from a U.S. Cohort: Demographic, Metabolic and Mental Health Correlates · Jerel P. Calzo · 2020 · 84 citations · Cited by this paper
  14. C-phycocyanin protects against obesity-associated type 2 diabetes-induced male fertility dysfunction via key enzyme regulation · 2026 · Related
  15. Efficacy and safety evaluation of SGLT2i on blood pressure control in patients with type 2 diabetes and hypertension: a new meta-analysis · Qin Zhang · 2023 · 73 citations · Cited by this paper
  16. A cross-species multi-omics analyze uncovers conserved molecular mechanisms underlying age-related erectile dysfunction · 2025 · Related
  17. Update of the position paper on arterial hypertension and erectile dysfunction · Margus Viigimaa · 2020 · 65 citations · Cited by this paper
  18. Efficacy of short message service (SMS) intervention on medication adherence and knowledge of stroke prevention among clinic attendees at risk of stroke: a randomized controlled trial · 2025 · Related
  19. Drugs Affecting Body Weight, Body Fat Distribution, and Metabolic Function—Mechanisms and Possible Therapeutic or Preventive Measures: an Update · Ann A. Verhaegen · 2021 · 55 citations · Cited by this paper
  20. Hypertension precision medicine: the promise and pitfalls of pharmacogenomics · 2025 · Related
  21. Erectile function in men with type 2 diabetes treated with dulaglutide: an exploratory analysis of the REWIND placebo-controlled randomised trial · HARPREET SINGH BAJAJ · 2021 · 55 citations · Cited by this paper
  22. Princeton IV consensus guidelines: PDE5 inhibitors and cardiac health · Robert Alan Kloner · 2023 · 55 citations · Cited by this paper
  23. The management of erectile dysfunction in men with diabetes mellitus unresponsive to phosphodiesterase type 5 inhibitors · Axel Alberto Cayetano-Alcaráz · 2022 · 52 citations · Cited by this paper
  24. Erectile dysfunction and adherence to antihypertensive therapy: Focus on β-blockers · Athanasios J. Manolis · 2020 · 43 citations · Cited by this paper
  25. The Evolving Role of Calcium Channel Blockers in Hypertension Management: Pharmacological and Clinical Considerations · Kamryn E. Jones · 2024 · 43 citations · Cited by this paper
  26. Long‐acting glucagon‐like peptide 1 receptor agonists boost erectile function in men with type 2 diabetes mellitus complaining of erectile dysfunction: A retrospective cohort study · Giuseppe Lisco · 2023 · 42 citations · Cited by this paper
  27. Relationship Between Hypertension, Antihypertensive Drugs and Sexual Dysfunction in Men and Women: A Literature Review · Inmaculada Xu Lou · 2023 · 42 citations · Cited by this paper
  28. Effect of icariside II and metformin on penile erectile function, glucose metabolism, reaction oxygen species, superoxide dismutase, and mitochondrial autophagy in type 2 diabetic rats with erectile dysfunction · Jian Zhang · 2020 · 37 citations · Cited by this paper
  29. Effects of Major Antihypertensive Drug Classes on Erectile Function: a Network Meta-analysis · Ioannis T. Farmakis · 2021 · 37 citations · Cited by this paper
  30. Characteristics and molecular mechanisms through which SGLT2 inhibitors improve metabolic diseases: A mechanism review · Lingli Xie · 2022 · 31 citations · Cited by this paper
  31. Effect of Icariside II and Metformin on Penile Erectile Function, Histological Structure, Mitochondrial Autophagy, Glucose-Lipid Metabolism, Angiotensin II and Sex Hormone in Type 2 Diabetic Rats With Erectile Dysfunction · Jian Zhang · 2020 · 29 citations · Cited by this paper
  32. Association of erectile dysfunction and type II diabetes mellitus at a tertiary care centre of south India · Sreeharsha Nutalapati · 2020 · 28 citations · Cited by this paper
  33. Comparison of Antihypertensive Drug Classes for Dementia Prevention · Venexia M. Walker · 2020 · 28 citations · Cited by this paper
  34. Time in Target Range for Blood Pressure and Adverse Health Outcomes: A Systematic Review · Heping Wang · 2025 · 26 citations · Cited by this paper
  35. Angiotensin Receptor Blockers for Erectile Dysfunction in Hypertensive Men: A Brief Meta-Analysis of Randomized Control Trials · Shaiful Bahari Ismail · 2019 · 25 citations · Cited by this paper
  36. Understanding Erectile Dysfunction in Hypertensive Patients: The Need for Good Patient Management · Jorge Hernández-Cerdá · 2020 · 25 citations · Cited by this paper
  37. Diabetes associated with hypertension exacerbated oxidative stress–mediated inflammation, apoptosis and autophagy leading to erectile dysfunction in rats · Chih-Ching Yang · 2022 · 23 citations · Cited by this paper
  38. Erectile dysfunction and associated risk factors in male patients with ischemic stroke · Hengheng Dai · 2020 · 22 citations · Cited by this paper
  39. Effects of Anti-Diabetic Drugs on Erectile Dysfunction: A Systematic Review and Meta-Analysis · Bo Yang · 2025 · 21 citations · Cited by this paper

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