Research map: PANoptosis in the pathogenesis of myelodysplastic syndromes

Back to the article

Papers in this map

  1. The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors · Taro Kawai · 2010 · 9360 citations · Cited by this paper
  2. Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective · 2026 · Related
  3. Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin · Yupeng Wang · 2017 · 3285 citations · Cited by this paper
  4. Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients · 2026 · Related
  5. Cytokine Storm · David C. Fajgenbaum · 2020 · 3279 citations · Cited by this paper
  6. Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer · 2026 · Related
  7. Regulation and Function of NF-κB Transcription Factors in the Immune System · Sivakumar Vallabhapurapu · 2009 · 2600 citations · Cited by this paper
  8. Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer · 2026 · Related
  9. Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes · Rajendra Karki · 2020 · 1768 citations · Cited by this paper
  10. Translating whole‐genome doubling into precision medicine in cancer · 2026 · Related
  11. Molecular mechanisms and functions of pyroptosis, inflammatory caspases and inflammasomes in infectious diseases · Si Ming Man · 2017 · 1725 citations · Cited by this paper
  12. Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr ‐mutated lung cancer · 2026 · Related
  13. Innate Immune Pattern Recognition: A Cell Biological Perspective · Sky W. Brubaker · 2015 · 1488 citations · Cited by this paper
  14. NKCC1 : A key regulator of glioblastoma progression · 2026 · Related
  15. SomaticSF3B1Mutation in Myelodysplasia with Ring Sideroblasts · Elli Papaemmanuil · 2011 · 1239 citations · Cited by this paper
  16. EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas · 2026 · Related
  17. Caspase-8 is the molecular switch for apoptosis, necroptosis and pyroptosis · Melanie Fritsch · 2019 · 1179 citations · Cited by this paper
  18. Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis · 2026 · Related
  19. cIAP1 and cIAP2 Facilitate Cancer Cell Survival by Functioning as E3 Ligases that Promote RIP1 Ubiquitination · Mathieu J.M. Bertrand · 2008 · 1108 citations · Cited by this paper
  20. Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology · 2026 · Related
  21. Pathogen blockade of TAK1 triggers caspase-8–dependent cleavage of gasdermin D and cell death · Pontus Ørning · 2018 · 1079 citations · Cited by this paper
  22. Programmed cell death as a defence against infection · Ine Jørgensen · 2017 · 1070 citations · Cited by this paper
  23. Identification of RPS14 as a 5q- syndrome gene by RNA interference screen · Benjamin L. Ebert · 2008 · 936 citations · Cited by this paper
  24. Caspase-8 induces cleavage of gasdermin D to elicit pyroptosis during Yersinia infection · Joseph Sarhan · 2018 · 920 citations · Cited by this paper
  25. NINJ1 mediates plasma membrane rupture during lytic cell death · Nobuhiko Kayagaki · 2021 · 870 citations · Cited by this paper
  26. ZBP1/DAI is an innate sensor of influenza virus triggering the NLRP3 inflammasome and programmed cell death pathways · Teneema Kuriakose · 2016 · 828 citations · Cited by this paper
  27. Recruitment of the Linear Ubiquitin Chain Assembly Complex Stabilizes the TNF-R1 Signaling Complex and Is Required for TNF-Mediated Gene Induction · Tobias L. Haas · 2009 · 785 citations · Cited by this paper
  28. ZBP1 and TAK1: Master Regulators of NLRP3 Inflammasome/Pyroptosis, Apoptosis, and Necroptosis (PAN-optosis) · R. K. Subbarao Malireddi · 2019 · 750 citations · Cited by this paper
  29. TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo · Jae‐Hyuck Shim · 2005 · 738 citations · Cited by this paper
  30. RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL · Kate E. Lawlor · 2015 · 657 citations · Cited by this paper
  31. Polo-like kinases: conservation and divergence in their functions and regulation · Vincent Archambault · 2009 · 619 citations · Cited by this paper
  32. RIP1 autophosphorylation is promoted by mitochondrial ROS and is essential for RIP3 recruitment into necrosome · Yingying Zhang · 2017 · 617 citations · Cited by this paper
  33. SRSF2 Mutations Contribute to Myelodysplasia by Mutant-Specific Effects on Exon Recognition · Eun Hee Kim · 2015 · 595 citations · Cited by this paper
  34. RIP Kinase-Dependent Necrosis Drives Lethal Systemic Inflammatory Response Syndrome · Linde Duprez · 2011 · 595 citations · Cited by this paper
  35. Luspatercept in Patients with Lower-Risk Myelodysplastic Syndromes · Pierre Fenaux · 2020 · 555 citations · Cited by this paper
  36. The Death Domain Superfamily in Intracellular Signaling of Apoptosis and Inflammation · Hyun Ho Park · 2007 · 535 citations · Cited by this paper
  37. Receptor-interacting protein kinase 1 (RIPK1) as a therapeutic target · Lauren Mifflin · 2020 · 514 citations · Cited by this paper
  38. Cleavage of GSDME by caspase-3 determines lobaplatin-induced pyroptosis in colon cancer cells · Junhui Yu · 2019 · 498 citations · Cited by this paper
  39. Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner · Stephanie A. Conos · 2017 · 488 citations · Cited by this paper

Source: OpenAlex (CC0)