Research map: Chicken-derived phage display antibodies against ASARM for calcification and phosphate research

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  1. A hyperconversion mechanism generates the chicken light chain preimmune repertoire · Claude–Agnès Reynaud · 1987 · 686 citations · Cited by this paper
  2. Trends in anti-osteoporosis pharmacotherapy and pharmacological initiation for secondary fracture prevention in Japan, 2017–2023 · 2026 · Related
  3. Somatic hyperconversion diversifies the single VH gene of the chicken with a high incidence in the D region · Claude–Agnès Reynaud · 1989 · 479 citations · Cited by this paper
  4. Unsupervised machine learning derived bone phenotypes exhibit differential biomarker responses following acute ballistic loaded exercise · 2026 · Related
  5. MEPE, a New Gene Expressed in Bone Marrow and Tumors Causing Osteomalacia · Peter S. Rowe · 2000 · 367 citations · Cited by this paper
  6. Perspective on unmet need for effective treatment in fibrous dysplasia and rare paediatric bone disease · 2026 · Related
  7. Somatic diversification of the chicken immunoglobulin light chain gene is limited to the rearranged variable gene segment · Craig B. Thompson · 1987 · 283 citations · Cited by this paper
  8. Roles of circulating proteins in osteoporosis pathogenesis: Insights from Mendelian randomization · 2026 · Related
  9. MEPE has the properties of an osteoblastic phosphatonin and minhibin · Peter S. Rowe · 2003 · 271 citations · Cited by this paper
  10. Gut microbiome and avascular necrosis: A scoping review of current evidence and knowledge gaps · 2026 · Related
  11. Sclerostin is a locally acting regulator of late-osteoblast/preosteocyte differentiation and regulates mineralization through a MEPE-ASARM-dependent mechanism · Gerald J. Atkins · 2011 · 241 citations · Cited by this paper
  12. Body composition and energy expenditure of patients with Fibrodysplasia Ossificans Progressiva · 2026 · Related
  13. MEPE-ASARM Peptides Control Extracellular Matrix Mineralization by Binding to Hydroxyapatite: An Inhibition Regulated by PHEX Cleavage of ASARM · William N. Addison · 2008 · 214 citations · Cited by this paper
  14. The fracture healing diet. Can nutritional supplements enhance osteogenic potential and fracture healing? A scoping review of current literature · 2026 · Related
  15. Degradation of MEPE, DMP1, and Release of SIBLING ASARM-Peptides (Minhibins): ASARM-Peptide(s) Are Directly Responsible for Defective Mineralization in HYP · Aline Martin · 2007 · 171 citations · Cited by this paper
  16. Complexity of genomic diagnosis: Lessons learnt from the UK Biobank and Generation study newborn genome sequencing analyses · 2026 · Related
  17. Surface plasmon resonance (SPR) confirms that MEPE binds to PHEX via the MEPE–ASARM motif: a model for impaired mineralization in X-linked rickets (HYP) · Peter S. Rowe · 2004 · 151 citations · Cited by this paper
  18. Partial lumbar spine response in hip non-responders to romosozumab: Baseline bone mineral density as the principal determinant in a multi-center real-world Japanese cohort (n = 398) · 2026 · Related
  19. Serum MEPE-ASARM-peptides are elevated in X-linked rickets (HYP): implications for phosphaturia and rickets · Doron Bresler · 2004 · 115 citations · Cited by this paper
  20. MRI reveals selective recovery in bone microarchitecture two years following kidney transplantation · 2026 · Related
  21. Selection of specific phage-display antibodies using libraries derived from chicken immunoglobulin genes · Evelyn Davies · 1995 · 111 citations · Cited by this paper
  22. Matrix Extracellular Phosphoglycoprotein (MEPE) Is a New Bone Renal Hormone and Vascularization Modulator · Valentin David · 2009 · 107 citations · Cited by this paper
  23. Phosphorylated acidic serine–aspartate-rich MEPE-associated motif peptide from matrix extracellular phosphoglycoprotein inhibits phosphate regulating gene with homologies to endopeptidases on the X-chromosome enzyme activity · Shiguang Liu · 2007 · 91 citations · Cited by this paper
  24. MEPE-Derived ASARM Peptide Inhibits Odontogenic Differentiation of Dental Pulp Stem Cells and Impairs Mineralization in Tooth Models of X-Linked Hypophosphatemia · Benjamin Jean Rene Salmon · 2013 · 68 citations · Cited by this paper
  25. MEPE’s Diverse Effects on Mineralization · Adele L. Boskey · 2009 · 63 citations · Cited by this paper
  26. ASARM peptides: PHEX-dependent and -independent regulation of serum phosphate · Valentin David · 2010 · 62 citations · Cited by this paper
  27. A large semi-synthetic single-chain Fv phage display library based on chicken immunoglobulin genes · Wouter Van Wyngaardt · 2004 · 60 citations · Cited by this paper
  28. Correction of the mineralization defect in hyp mice treated with protease inhibitors CA074 and pepstatin · Peter S. Rowe · 2006 · 56 citations · Cited by this paper
  29. MEPE is a novel regulator of growth plate cartilage mineralization · Katherine Ann Staines · 2012 · 50 citations · Cited by this paper
  30. Age dependent regulation of bone-mass and renal function by the MEPE ASARM-motif · Lesya V. Zelenchuk · 2015 · 39 citations · Cited by this paper
  31. Abnormal Presence of the Matrix Extracellular Phosphoglycoprotein-Derived Acidic Serine- and Aspartate-Rich Motif Peptide in Human Hypophosphatemic Dentin · Tchilalo Boukpessi · 2010 · 39 citations · Cited by this paper
  32. Dentin Noncollagenous Matrix Proteins in Familial Hypophosphatemic Rickets · Céline Gaucher · 2008 · 29 citations · Cited by this paper
  33. Evocalcet Rescues Secondary Hyperparathyroidism-driven Cortical Porosity in CKD Male Rats · Tomoka Hasegawa · 2023 · 29 citations · Cited by this paper
  34. An Improved Phage Display Antibody Cloning System Using Newly Designed PCR Primers Optimized for Pfu DNA Polymerase · Hachiro I. Yamanaka · 1995 · 27 citations · Cited by this paper
  35. PHEX Mimetic (SPR4-Peptide) Corrects and Improves HYP and Wild Type Mice Energy-Metabolism · Lesya V. Zelenchuk · 2014 · 19 citations · Cited by this paper
  36. Expression vectors for chicken–human chimeric antibodies · Nahoko Nishibori · 2004 · 17 citations · Cited by this paper
  37. Do ASARM peptides play a role in nephrogenic systemic fibrosis? · Peter S. Rowe · 2015 · 15 citations · Cited by this paper
  38. SPR4-peptide alters bone metabolism of normal and HYP mice · Lesya V. Zelenchuk · 2014 · 14 citations · Cited by this paper
  39. Active sites of human MEPE-ASARM regulating bone matrix mineralization · Tomoko Minamizaki · 2020 · 8 citations · Cited by this paper

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