Research map: Cognitive function in the context of pharmacogenetic CYP2D6 variability and anticholinergic burden in older adults – results from the ActiFE study

Back to the article

Papers in this map

  1. “Mini-mental state” · Marshal F. Folstein · 1975 · 87558 citations · Cited by this paper
  2. Response to “Comment on cognitive function in the context of pharmacogenetic CYP2D6 variability and anticholinergic burden in older adults – results from the ActiFE study” · Linda Lorenz · 2026 · Cites this paper
  3. The Effect of the combination therapy of statin and dapagliflozin, a selective inhibitor of sodium_glucose Co-transporter type 2, in the treatment of Ischemic heart disease with heart failure: A randomized controlled trial · 2026 · Related
  4. Dementia prevention, intervention, and care · Gill Livingston · 2017 · 6275 citations · Cited by this paper
  5. Acetaminophen exposure in an aging population and neurodegenerative outcomes · 2026 · Related
  6. American Geriatrics Society 2019 Updated AGS Beers Criteria® for Potentially Inappropriate Medication Use in Older Adults · By the 2019 American Geriatrics Society Beers Criteria® Update Expert Panel · 2019 · 3220 citations · Cited by this paper
  7. Population pharmacokinetics of unbound imipenem in critically ill patients: a comparison of five renal function estimators for PK/PD-guided dosing · 2026 · Related
  8. Pharmacogenomics: Translating Functional Genomics into Rational Therapeutics · William Edward Evans · 1999 · 2499 citations · Cited by this paper
  9. Faster dementia progression was associated with use of potentially inappropriate medications · 2026 · Related
  10. CENTRAL CHOLINERGIC SYSTEMS AND COGNITION · Barry J. Everitt · 1997 · 1359 citations · Cited by this paper
  11. Examining the risk of neurotoxicity in patients who receive unadjusted doses of oral beta-lactams in renal insufficiency: a retrospective cohort study · 2026 · Related
  12. Mini-Mental State Examination (MMSE) for the detection of Alzheimer's disease and other dementias in people with mild cognitive impairment (MCI) · Ingrid Arévalo-Rodríguez · 2015 · 850 citations · Cited by this paper
  13. Secondary data analysis of Adverse Drug Reactions reported by healthcare professionals and patients: interventions to manage ADRs of ACE inhibitors and ARBs · 2026 · Related
  14. Impact of Anticholinergics on the Aging Brain: A Review and Practical Application · Malaz A. Boustani · 2008 · 845 citations · Cited by this paper
  15. Detection of intravenous drug physicochemical incompatibilities in clinical practice: e-Harvis compared to reference tools · 2026 · Related
  16. Polymorphism of Human Cytochrome P450 2D6 and Its Clinical Significance · Shufeng Zhou · 2009 · 765 citations · Cited by this paper
  17. Effects of renal impairment on the pharmacokinetics, safety, and tolerability of pudexacianinium (ASP5354) after IV administration: a mechanistic exploration · 2026 · Related
  18. Social Isolation and Loneliness · Aparna Shankar · 2013 · 650 citations · Cited by this paper
  19. Authors response to the comments by Muhammad Salman, Muhammad Hammad Chola and Muhammad Hasan on our paper “prescribing patterns of glucagon like peptide-1 receptor agonists in the Swedish capital region: a register-based cross-sectional study” · 2026 · Related
  20. Anticholinergic burden quantified by anticholinergic risk scales and adverse outcomes in older people: a systematic review · Mohammed Saji Salahudeen · 2015 · 553 citations · Cited by this paper
  21. Response to comment on “CYP2C19 genotyping and mavacamten: predicting outcomes in normal, intermediate and rapid metabolisers in obstructive hypertrophic cardiomyopathy” · 2026 · Related
  22. Standardizing CYP 2D6 Genotype to Phenotype Translation: Consensus Recommendations from the Clinical Pharmacogenetics Implementation Consortium and Dutch Pharmacogenetics Working Group · Kelly E. Caudle · 2019 · 552 citations · Cited by this paper
  23. Drugs with anticholinergic effects and cognitive impairment, falls and all‐cause mortality in older adults: A systematic review and meta‐analysis · Kimberley Ruxton · 2015 · 374 citations · Cited by this paper
  24. Addressing phenoconversion: the Achilles' heel of personalized medicine · Rashmi R. Shah · 2014 · 275 citations · Cited by this paper
  25. Association of Anticholinergic Burden with Cognitive and Functional Status in a Cohort of Hospitalized Elderly: Comparison of the Anticholinergic Cognitive Burden Scale and Anticholinergic Risk Scale · Luca Pasina · 2012 · 194 citations · Cited by this paper
  26. Phenoconversion of Cytochrome P450 Metabolism: A Systematic Review · Sylvia D. Klomp · 2020 · 184 citations · Cited by this paper
  27. Temporal trends in anticholinergic medication prescription in older people: repeated cross-sectional analysis of population prescribing data · Deepa Sumukadas · 2013 · 122 citations · Cited by this paper
  28. Anticholinergic burden: considerations for older adults · Lisa Kouladjian O’Donnell · 2016 · 74 citations · Cited by this paper
  29. Drugs With Anticholinergic Properties as a Risk Factor for Cognitive Impairment in Elderly People · Iacopo Cancelli · 2008 · 71 citations · Cited by this paper
  30. Accelerometer-based physical activity in a large observational cohort - study protocol and design of the activity and function of the elderly in Ulm (ActiFE Ulm) study · ActiFE Ulm Study Group · 2010 · 67 citations · Cited by this paper
  31. Impact of CYP2D6 Functional Allelic Variations on Phenoconversion and Drug–Drug Interactions · Flavia Storelli · 2017 · 63 citations · Cited by this paper
  32. Association of Anticholinergic Drug Burden with Cognitive and Functional Decline Over Time in Older Inpatients: Results from the CRIME Project · Gloria Brombo · 2018 · 49 citations · Cited by this paper
  33. Anticholinergic Burden in Children, Adults and Older Adults in Slovenia: A Nationwide Database Study · Nanča Čebron Lipovec · 2020 · 42 citations · Cited by this paper
  34. Accurately Genotyping CYP2D6 : Not for the Faint of Heart · Charity Nofziger · 2018 · 39 citations · Cited by this paper
  35. Association Between Inherited CYP2D6/2C19 Phenotypes and Anticholinergic Measures in Elderly Patients Using Anticholinergic Drugs · Hege Kersten · 2013 · 15 citations · Cited by this paper
  36. The Role of Smoking, Obesity, and Physical Inactivity in Cognitive Performance and Decline: A Multicohort Study · Chenlu Hong · 2023 · 14 citations · Cited by this paper
  37. Anticholinergic Risk and Frequency of Anticholinergic Drug Prescriptions in a Population Older Than 65 · Jorge Enrique Machado‐Alba · 2016 · 13 citations · Cited by this paper
  38. Anticholinergic burden in middle and older age is associated with lower cognitive function, but not with brain atrophy · Jure Mur · 2023 · 12 citations · Cited by this paper
  39. Anticholinergic action is rarely a good thing · Delia Bishara · 2023 · 12 citations · Cited by this paper

Source: OpenAlex (CC0)