Research map: The microbiota-host metabolic axis in cervical cancer: from homeostatic disruption to mechanisms of therapy resistance

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  1. Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries · Freddie Bray · 2024 · 26051 citations · Cited by this paper
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  19. Causal attribution of human papillomavirus genotypes to invasive cervical cancer worldwide: a systematic analysis of the global literature · Feixue Wei · 2024 · 303 citations · Cited by this paper
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  21. Linking cervicovaginal immune signatures, HPV and microbiota composition in cervical carcinogenesis in non-Hispanic and Hispanic women · Paweł Łaniewski · 2018 · 298 citations · Cited by this paper
  22. Tumor-resident Lactobacillus iners confer chemoradiation resistance through lactate-induced metabolic rewiring · Lauren Elizabeth Colbert · 2023 · 273 citations · Cited by this paper
  23. Signaling networks in immunometabolism · Jordy Saravia · 2020 · 251 citations · Cited by this paper
  24. Vaginal lactic acid elicits an anti-inflammatory response from human cervicovaginal epithelial cells and inhibits production of pro-inflammatory mediators associated with HIV acquisition · Anna C. Hearps · 2017 · 234 citations · Cited by this paper
  25. Assessment of the Capacity of Lactobacillus to Inhibit the Growth of Uropathogens and Block Their Adhesion to Vaginal Epithelial Cells · Jordi Osset · 2001 · 212 citations · Cited by this paper
  26. Nuclear GTPSCS functions as a lactyl-CoA synthetase to promote histone lactylation and gliomagenesis · Ruilong Liu · 2024 · 207 citations · Cited by this paper
  27. L- and D-lactate enhance DNA repair and modulate the resistance of cervical carcinoma cells to anticancer drugs via histone deacetylase inhibition and hydroxycarboxylic acid receptor 1 activation · W. C. Wagner · 2015 · 194 citations · Cited by this paper
  28. Lactate limits CNS autoimmunity by stabilizing HIF-1α in dendritic cells · Liliana María Sanmarco · 2023 · 192 citations · Cited by this paper
  29. Vaginal concentrations of lactic acid potently inactivate HIV · Muriel Aldunate · 2013 · 186 citations · Cited by this paper
  30. Dysfunction of exhausted T cells is enforced by MCT11-mediated lactate metabolism · Ronal M. Peralta · 2024 · 173 citations · Cited by this paper
  31. Distinct Immune Responses Elicited From Cervicovaginal Epithelial Cells by Lactic Acid and Short Chain Fatty Acids Associated With Optimal and Non-optimal Vaginal Microbiota · David Jose Delgado-Diaz · 2020 · 165 citations · Cited by this paper
  32. HPV infection alters vaginal microbiome through down-regulating host mucosal innate peptides used by Lactobacilli as amino acid sources · Alizée Lebeau · 2022 · 161 citations · Cited by this paper
  33. Crosstalk Between Female Gonadal Hormones and Vaginal Microbiota Across Various Phases of Women’s Gynecological Lifecycle · Harrisham Kaur · 2020 · 154 citations · Cited by this paper
  34. PI3K/AKT/mTOR Signaling Regulates the Virus/Host Cell Crosstalk in HPV-Positive Cervical Cancer Cells · Felicitas Bossler · 2019 · 153 citations · Cited by this paper
  35. Antimicrobial properties of Lactobacillus cell‐free supernatants against multidrug‐resistant urogenital pathogens · Marina Scillato · 2021 · 153 citations · Cited by this paper
  36. The Cervicovaginal Mucus Barrier · Guillaume Lacroix · 2020 · 149 citations · Cited by this paper
  37. Autocrine STAT3 activation in HPV positive cervical cancer through a virus-driven Rac1—NFκB—IL-6 signalling axis · Ethan L. Morgan · 2019 · 142 citations · Cited by this paper
  38. FASN promotes lymph node metastasis in cervical cancer via cholesterol reprogramming and lymphangiogenesis · Qiqiao Du · 2022 · 142 citations · Cited by this paper
  39. Suppression of Antitumor Immune Responses by Human Papillomavirus through Epigenetic Downregulation of CXCL14 · Louis Cicchini · 2016 · 124 citations · Cited by this paper

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