Research map: From ROS Signaling to Redox Resistance in Exercise and Metabolic Disease

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  1. Oxidative stress: a concept in redox biology and medicine · Helmut Sies · 2015 · 3032 citations · Cited by this paper
  2. Longitudinal changes between 24-h movement guidelines and academic performance in secondary school students: DADOS study · 2025 · Related
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  7. Exercise-Induced Oxidative Stress: Cellular Mechanisms and Impact on Muscle Force Production · Scott K. Powers · 2008 · 2451 citations · Cited by this paper
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  10. Is exercise induced oxidative stress a friend or a foe? · 2026 · Related
  11. Antioxidants prevent health-promoting effects of physical exercise in humans · Michael Ristow · 2009 · 1583 citations · Cited by this paper
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  13. Distinct Cysteine Residues in Keap1 Are Required for Keap1-Dependent Ubiquitination of Nrf2 and for Stabilization of Nrf2 by Chemopreventive Agents and Oxidative Stress · Donna D. Zhang · 2003 · 1476 citations · Cited by this paper
  14. The effect and mechanism of aerobic exercise on mitochondrial structure and function in skeletal muscle of CAV-3 knockout mice · 2026 · Related
  15. AMPK and PPARδ Agonists Are Exercise Mimetics · Vihang A. Narkar · 2008 · 1219 citations · Cited by this paper
  16. Fat mass and lean soft tissue mass moderate the association between handgrip strength indexes with bone parameters among adolescent athletes · 2025 · Related
  17. Low antioxidant enzyme gene expression in pancreatic islets compared with various other mouse tissues · Slgurd Lenzen · 1996 · 1169 citations · Cited by this paper
  18. Postural stability and muscle function responses to acute brisk walking in young and middle-aged women · 2025 · Related
  19. Relation Between Antioxidant Enzyme Gene Expression and Antioxidative Defense Status of Insulin-Producing Cells · Markus Tiedge · 1997 · 1166 citations · Cited by this paper
  20. Update: Is exercise-induced oxidative stress a friend or foe? · 2026 · Related
  21. Keap1-dependent Proteasomal Degradation of Transcription Factor Nrf2 Contributes to the Negative Regulation of Antioxidant Response Element-driven Gene Expression · Michael J. McMahon · 2003 · 1151 citations · Cited by this paper
  22. The role of exercise and PGC1α in inflammation and chronic disease · Christoph Handschin · 2008 · 1092 citations · Cited by this paper
  23. Pancreatic β-cells in type 1 and type 2 diabetes mellitus: different pathways to failure · Decio Laks Eizirik · 2020 · 887 citations · Cited by this paper
  24. Oral administration of vitamin C decreases muscle mitochondrial biogenesis and hampers training-induced adaptations in endurance performance · Mari Carmen Gómez‐Cabrera · 2008 · 845 citations · Cited by this paper
  25. Use of Cells Expressing γ Subunit Variants to Identify Diverse Mechanisms of AMPK Activation · Simon A. Hawley · 2010 · 778 citations · Cited by this paper
  26. Exercise Stimulates Pgc-1α Transcription in Skeletal Muscle through Activation of the p38 MAPK Pathway · Takayuki Akimoto · 2005 · 713 citations · Cited by this paper
  27. Regulation of Mitochondrial Biogenesis in Skeletal Muscle by CaMK · Haiyan Wu · 2002 · 686 citations · Cited by this paper
  28. Evidence that interleukin‐6 is produced in human skeletal muscle during prolonged running · Sisse Rye Ostrowski · 1998 · 679 citations · Cited by this paper
  29. Peroxiredoxins: guardians against oxidative stress and modulators of peroxide signaling · Arden Perkins · 2015 · 664 citations · Cited by this paper
  30. The pentose phosphate pathway in health and disease · Tara A. TeSlaa · 2023 · 653 citations · Cited by this paper
  31. A Liver-Derived Secretory Protein, Selenoprotein P, Causes Insulin Resistance · Hirofumi Misu · 2010 · 583 citations · Cited by this paper
  32. Reactive Oxygen Species as a Signal in Glucose-Stimulated Insulin Secretion · Jingbo Pi · 2007 · 579 citations · Cited by this paper
  33. Selective activation of AMPK‐PGC‐1α or PKB‐TSC2‐mTOR signaling can explain specific adaptive responses to endurance or resistance training‐like electrical muscle stimulation · Philip James Atherton · 2005 · 477 citations · Cited by this paper
  34. Decreasing xanthine oxidase‐mediated oxidative stress prevents useful cellular adaptations to exercise in rats · Mari Carmen Gómez‐Cabrera · 2005 · 476 citations · Cited by this paper
  35. Endurance Training in Humans Leads to Fiber Type-Specific Increases in Levels of Peroxisome Proliferator-Activated Receptor-γ Coactivator-1 and Peroxisome Proliferator-Activated Receptor-α in Skeletal Muscle · Aaron Paul Russell · 2003 · 456 citations · Cited by this paper
  36. Exposure to Hydrogen Peroxide Induces Oxidation and Activation of AMP-activated Protein Kinase* · Jaroslaw W. Zmijewski · 2010 · 449 citations · Cited by this paper
  37. PGC-1α regulation by exercise training and its influences on muscle function and insulin sensitivity · Vitor Agnew Lira · 2010 · 412 citations · Cited by this paper
  38. Reactive Oxygen Species in Skeletal Muscle Signaling · Elena Barbieri · 2011 · 410 citations · Cited by this paper
  39. Exercise intensity-dependent regulation of peroxisome proliferator-activated receptor γ coactivator-1α mRNA abundance is associated with differential activation of upstream signalling kinases in human skeletal muscle · Brendan Egan · 2010 · 371 citations · Cited by this paper

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