Research map: Large amyloid plaques associate with early behavioral alterations in 6-month-old APPswe/PS1dE9 mice
Back to the article
Papers in this map
QuPath: Open source software for digital pathology image analysis
· Peter Bankhead · 2017 · 9171 citations · Cited by this paper
Efficacy of Low Dose of Dihydroquercetin (DHQ) in Two Genetic Models of Neurodegeneration: Insights from FUS[1-359]-Tg and APPswe/PS1dE9 Paradigms
· Ekaterina A. Lysikova · 2026 · Cites this paper
A pediatric case of YAP1::MAML2 fusion-positive supratentorial ependymoma: A potential subtype of YAP1 -fused ependymoma
· 2026 · Related
Alzheimer's Disease: The Amyloid Cascade Hypothesis
· John Hardy · 1992 · 7593 citations · Cited by this paper
Comprehensive clinicomolecular characterization of a methylation-defined supratentorial high-grade astrocytoma with piloid features in a young adult with confirmed germline NF1 mutation
· 2026 · Related
Alzheimer's Disease
· Henry W. Querfurth · 2010 · 4534 citations · Cited by this paper
Somatic PIK3CA and PTEN mutations with endothelial PI3K/AKT/mTOR activation in RAS-negative brain arteriovenous malformations
· 2026 · Related
Phases of Aβ-deposition in the human brain and its relevance for the development of AD
· Dietmar Rudolf Thal · 2002 · 3614 citations · Cited by this paper
Novel YWHAE-NTRK3 fusion in a pediatric glioma
· 2026 · Related
National Institute on Aging–Alzheimer’s Association guidelines for the neuropathologic assessment of Alzheimer’s disease: a practical approach
· Thomas Jude Montine · 2011 · 2990 citations · Cited by this paper
GSK126 mitigates oxidative stress in Alzheimer disease models via an enhancer of Zeste homolog 2–H3 lysine 27 trimethylation–superoxide dismutase 1 axis
· 2026 · Related
Two Phase 3 Trials of Bapineuzumab in Mild-to-Moderate Alzheimer's Disease
· Stephen Salloway · 2014 · 1999 citations · Cited by this paper
Skin biopsy for detection of phosphorylated alpha-synuclein by indirect immunofluorescence: Diagnostic accuracy in a cohort of patients with cognitive impairment
· 2026 · Related
Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease – is this type 3 diabetes?
· Eric van Steen · 2005 · 1707 citations · Cited by this paper
Unusual immunohistochemical profiles in hemangioblastomas and their relevance in differential diagnosis: A comprehensive study of 112 cases
· 2026 · Related
Mutant presenilins specifically elevate the levels of the 42 residue β-amyloid peptide in vivo: evidence for augmentation of a 42-specific γ secretase
· Joanna L. Jankowsky · 2003 · 1631 citations · Cited by this paper
Comorbid neuropathologies but not Braak stage influence cognitive impairment in primary age-related tauopathy
· 2026 · Related
Tangle and neuron numbers, but not amyloid load, predict cognitive status in Alzheimer’s disease
· Pantéleimon Giannakopoulos · 2003 · 1147 citations · Cited by this paper
In This Issue
· 2026 · Related
Co-expression of multiple transgenes in mouse CNS: a comparison of strategies
· Joanna L. Jankowsky · 2001 · 846 citations · Cited by this paper
Immunomodulatory effects of new phytotherapy on human macrophages and TLR4- and TLR7/8-mediated viral-like inflammation in mice
· 2022 · Related
Characterization of amyloid deposition in the APPswe/PS1dE9 mouse model of Alzheimer disease
· Mónica Garcı́a-Alloza · 2006 · 770 citations · Cited by this paper
Early Aβ accumulation and progressive synaptic loss, gliosis, and tangle formation in AD brain
· Martin Ingelsson · 2004 · 669 citations · Cited by this paper
Claudin-5: gatekeeper of neurological function
· Chris Greene · 2019 · 602 citations · Cited by this paper
Loss of the Presynaptic Vesicle Protein Synaptophysin in Hippocampus Correlates with Cognitive Decline in Alzheimer Disease
· Chun‐I Sze · 1997 · 578 citations · Cited by this paper
Gender and incidence of dementia in the Framingham Heart Study from mid‐adult life
· Geneviève Chêne · 2014 · 536 citations · Cited by this paper
Myelin dysfunction drives amyloid-β deposition in models of Alzheimer’s disease
· Constanze Depp · 2023 · 471 citations · Cited by this paper
Management of agitation and aggression associated with Alzheimer disease
· Clive G. Ballard · 2009 · 412 citations · Cited by this paper
The complexity of Alzheimer’s disease: an evolving puzzle
· Camilla Ferrari · 2021 · 310 citations · Cited by this paper
Past, present and future of therapeutic strategies against amyloid-β peptides in Alzheimer’s disease: a systematic review
· Danko Jeremic · 2021 · 309 citations · Cited by this paper
Characterizing the Appearance and Growth of Amyloid Plaques in APP/PS1 Mice
· Ping Yan · 2009 · 273 citations · Cited by this paper
Amyloidosis in Alzheimer’s Disease: Pathogeny, Etiology, and Related Therapeutic Directions
· Chen Ma · 2022 · 237 citations · Cited by this paper
Nucleation-Dependent Polymerization Is an Essential Component of Amyloid-Mediated Neuronal Cell Death
· Mark D. Wogulis · 2005 · 234 citations · Cited by this paper
Monoamine oxidase B is elevated in Alzheimer disease neurons, is associated with γ-secretase and regulates neuronal amyloid β-peptide levels
· Sophia Schedin‐Weiss · 2017 · 233 citations · Cited by this paper
Prefrontal Cortex Regulates Sensory Filtering through a Basal Ganglia-to-Thalamus Pathway
· Miho Nakajima · 2019 · 230 citations · Cited by this paper
Mouse Models of Alzheimer’s Disease
· Miyabishara Yokoyama · 2022 · 216 citations · Cited by this paper
Measuring behavior in mice with chronic stress depression paradigm
· Tatyana V. Strekalova · 2009 · 214 citations · Cited by this paper
β-Amyloid Clustering around ASC Fibrils Boosts Its Toxicity in Microglia
· Lea Lydia Friker · 2020 · 201 citations · Cited by this paper
SQSTM1/p62: A Potential Target for Neurodegenerative Disease
· Shifan Ma · 2019 · 199 citations · Cited by this paper
Source: OpenAlex (CC0)