Research map: High Expression of PgRMC1 Correlates with Poor Neoadjuvant Chemotherapy Response and Alters Chemosensitivity in Breast Cancer Cells

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  1. Relevance of breast cancer hormone receptors and other factors to the efficacy of adjuvant tamoxifen: patient-level meta-analysis of randomised trials · Early Breast Cancer Trialists' Collaborative Group (EBCTCG) · 2011 · 3125 citations · Cited by this paper
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  14. Analytical Validation of Quantitative Polymerase Chain Reaction and AscentTM Low-Pass Whole Genome Sequencing to Report on Gene Copy Number Variants in Cerebrospinal Fluid Tumor-Derived DNA · 2026 · Related
  15. PGRMC1 (progesterone receptor membrane component 1): A targetable protein with multiple functions in steroid signaling, P450 activation and drug binding · Hannah J. Rohe · 2008 · 218 citations · Cited by this paper
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  17. Full-Length cDNA Sequence of a Progesterone Membrane-Binding Protein from Porcine Vascular Smooth Muscle Cells · Elisabeth Falkenstein · 1996 · 215 citations · Cited by this paper
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  21. Haem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistance · Yasuaki Kabe · 2016 · 198 citations · Cited by this paper
  22. Pgrmc1 (Progesterone Receptor Membrane Component 1) Associates with Epidermal Growth Factor Receptor and Regulates Erlotinib Sensitivity · Ikhlas Ahmed · 2010 · 135 citations · Cited by this paper
  23. Breast cancer subtyping by immunohistochemistry and histological grade outperforms breast cancer intrinsic subtypes in predicting neoadjuvant chemotherapy response · Esther H. Lips · 2013 · 120 citations · Cited by this paper
  24. Progesterone Increases the Release of Brain-Derived Neurotrophic Factor from Glia via Progesterone Receptor Membrane Component 1 (Pgrmc1)-Dependent ERK5 Signaling · Chang Su · 2012 · 100 citations · Cited by this paper
  25. Membrane Progesterone Receptors (mPRs, PAQRs): Review of Structural and Signaling Characteristics · Peter Thomas · 2022 · 93 citations · Cited by this paper
  26. GEPIA3: Enhanced drug sensitivity and interaction network analysis for cancer research · Yujian James Kang · 2025 · 79 citations · Cited by this paper
  27. Endometrial miR-181a and miR-98 Expression Is Altered during Transition from Normal into Cancerous State and TargetPGR,PGRMC1,CYP19A1,DDX3X, andTIMP3 · Harekrushna Panda · 2012 · 77 citations · Cited by this paper
  28. Membrane-initiated effects of progesterone on proliferation and activation of VEGF in breast cancer cells · Hans J. Neubauer · 2009 · 76 citations · Cited by this paper
  29. Hpr6 (Heme-1 Domain Protein) Regulates the Susceptibility of Cancer Cells to Chemotherapeutic Drugs · Gerard Crudden · 2005 · 63 citations · Cited by this paper
  30. Progesterone Receptor Membrane Component-1 Regulates the Development and Cisplatin Sensitivity of Human Ovarian Tumors in Athymic Nude Mice · John J. Peluso · 2009 · 62 citations · Cited by this paper
  31. Differential Responses of Progesterone Receptor Membrane Component-1 (Pgrmc1) and the Classical Progesterone Receptor (Pgr) to 17β-Estradiol and Progesterone in Hippocampal Subregions that Support Synaptic Remodeling and Neurogenesis · Namrata Bali · 2011 · 60 citations · Cited by this paper
  32. Possible role of PGRMC1 in breast cancer development · Hans J. Neubauer · 2013 · 54 citations · Cited by this paper
  33. PGRMC1 Elevation in Multiple Cancers and Essential Role in Stem Cell Survival · Kaia K. Hampton · 2015 · 44 citations · Cited by this paper
  34. High Level of Progesteron Receptor Membrane Component 1 (PGRMC 1) in Tissue of Breast Cancer Patients is Associated with Worse Response to Anthracycline-Based Neoadjuvant Therapy · Marina Willibald · 2017 · 37 citations · Cited by this paper
  35. Progesterone receptor membrane component 1 as a potential prognostic biomarker for hepatocellular carcinoma · Hung-Wen Tsai · 2018 · 34 citations · Cited by this paper
  36. Many or too many progesterone membrane receptors? Clinical implications · Alexandra Wendler · 2022 · 27 citations · Cited by this paper
  37. PGRMC1 Promotes Progestin-Dependent Proliferation of Breast Cancer Cells by Binding Prohibitins Resulting in Activation of ERα Signaling · Yingxue Bai · 2021 · 26 citations · Cited by this paper
  38. Comprehensive Analysis of the Implication of PGRMC1 in Triple-Negative Breast Cancer · Xin Yi Xu · 2021 · 9 citations · Cited by this paper
  39. Expression of reprogramming factors in breast cancer cell lines and the regulation by activated Stat3 · Chul Min Yang · 2012 · 8 citations · Cited by this paper

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