Research map: Donor-specific immunomodulation is mediated by mechanisms beyond CD4 + regulatory T cells

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Papers in this map

  1. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells · Jason D. Fontenot · 2003 · 7785 citations · Cited by this paper
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  3. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases · Shimon Sakaguchi · 1995 · 5588 citations · Cited by this paper
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  5. Conversion of Peripheral CD4+CD25− Naive T Cells to CD4+CD25+ Regulatory T Cells by TGF-β Induction of Transcription Factor Foxp3 · WanJun Chen · 2003 · 4706 citations · Cited by this paper
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  9. HLA-Mismatched Renal Transplantation without Maintenance Immunosuppression · Tatsuo Kawai · 2013 · 1022 citations · Cited by this paper
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  11. HLA-Mismatched Renal Transplantation without Maintenance Immunosuppression · Tatsuo Kawai · 2008 · 980 citations · Cited by this paper
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  13. The cell proliferation-associated antigen of antibody Ki-67: a very large, ubiquitous nuclear protein with numerous repeated elements, representing a new kind of cell cycle-maintaining proteins. · Carsten Schlüter · 1993 · 780 citations · Cited by this paper
  14. Extracellular vesicles secreted by adipose-derived stem cells alleviate dedifferentiation and senescence in monolayer-expanded chondrocytes by suppressing interleukin-1β-induced MAPK signaling · 2026 · Related
  15. A pilot study of operational tolerance with a regulatory T‐cell‐based cell therapy in living donor liver transplantation · Satoru Todo · 2016 · 444 citations · Cited by this paper
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  17. Immunosuppressive Mechanisms of Regulatory B Cells · Diego Catalán · 2021 · 400 citations · Cited by this paper
  18. Cryopreservation of hepatocytes: Impact of long-term storage and organ donor factors on cell quality for clinical applications · 2026 · Related
  19. Anergic T Cells as Suppressor Cells in Vitro · Giovanna Lombardi · 1994 · 371 citations · Cited by this paper
  20. Immunophenotypic characterization and clinical relevance of passage number in umbilical cord mesenchymal stromal cells: A review · 2026 · Related
  21. Tr1 cells: From discovery to their clinical application · Manuela Battaglia · 2006 · 276 citations · Cited by this paper
  22. Clinical Grade Manufacturing of Human Alloantigen-Reactive Regulatory T Cells for Use in Transplantation · Amy L. Putnam · 2013 · 261 citations · Cited by this paper
  23. Interferon γ: a crucial role in the function of induced regulatory T cells in vivo · Kathryn J. Wood · 2006 · 207 citations · Cited by this paper
  24. SOCS1 is essential for regulatory T cell functions by preventing loss of Foxp3 expression as well as IFN-γ and IL-17A production · Reiko Takahashi · 2011 · 191 citations · Cited by this paper
  25. T reg cells limit IFN-γ production to control macrophage accrual and phenotype during skeletal muscle regeneration · Marisella Panduro · 2018 · 157 citations · Cited by this paper
  26. No Gains in Long-term Survival After Liver Transplantation Over the Past Three Decades · Abbas A. Rana · 2018 · 149 citations · Cited by this paper
  27. Immunosuppression in liver transplant · Tommaso Di Maira · 2020 · 138 citations · Cited by this paper
  28. TGF-β and kynurenines as the key to infectious tolerance · Maria Laura Belladonna · 2009 · 128 citations · Cited by this paper
  29. Trained immunity in organ transplantation · Jordi Ochando · 2019 · 112 citations · Cited by this paper
  30. REGULATION OF LYMPHOCYTE RESPONSES IN VITRO · Masaru Yoshinaga · 1972 · 110 citations · Cited by this paper
  31. Renal allograft rejection is prevented by adoptive transfer of anergic T cells in nonhuman primates · Hisashi Bashuda · 2005 · 98 citations · Cited by this paper
  32. Regulatory T cells inhibit acute IFN-γ synthesis without blocking T-helper cell type 1 (Th1) differentiation via a compartmentalized requirement for IL-10 · Dorothy K. Sojka · 2011 · 93 citations · Cited by this paper
  33. Tolerance in clinical liver transplantation · Josh Levitsky · 2017 · 86 citations · Cited by this paper
  34. Regulatory T cells in solid organ transplantation · Muhammad Atif · 2020 · 86 citations · Cited by this paper
  35. Mechanistic insights into the role of probiotics in modulating immune cells in ulcerative colitis · Ni Guo · 2023 · 85 citations · Cited by this paper
  36. Novel CD8+ Treg suppress EAE by TGF‐β‐ and IFN‐γ‐dependent mechanisms · Meiling Chen · 2009 · 83 citations · Cited by this paper
  37. IFNγ-induction of TH1-like regulatory T cells controls antiviral responses · Angela M. Gocher-Demske · 2023 · 69 citations · Cited by this paper
  38. Co‐operative action of interleukin‐10 and interferon‐γ to regulate dendritic cell functions · Yoshiki Yanagawa · 2008 · 68 citations · Cited by this paper
  39. The future of liver transplantation · Sandy Feng · 2024 · 64 citations · Cited by this paper

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