Research map: Curcumin as a multi-target therapeutic strategy in metabolic dysfunction-associated steatotic liver disease: integrating preclinical evidence with traditional chinese medicine perspectives

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  1. Bioavailability of Curcumin: Problems and Promises · Preetha Anand · 2007 · 5524 citations · Cited by this paper
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  11. Treatment of Non-alcoholic Fatty Liver Disease with Curcumin: A Randomized Placebo-controlled Trial · Sepideh Rahmani · 2016 · 458 citations · Cited by this paper
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  13. Metabolic dysfunction–associated steatotic liver disease: Update and impact of new nomenclature on the American Association for the Study of Liver Diseases practice guidance on nonalcoholic fatty liver disease · Fasiha Kanwal · 2023 · 379 citations · Cited by this paper
  14. Quercetin, kaempferol, baicalein, and ellagic acid in Guizhi Fuling Wan suppress Glioblastoma by inducing p21-mediated cell cycle arrest and mitochondrial apoptosis · 2026 · Related
  15. The Pathogenesis of Nonalcoholic Fatty Liver Disease: Interplay between Diet, Gut Microbiota, and Genetic Background · Jinsheng Yu · 2016 · 205 citations · Cited by this paper
  16. Mechanistic pharmacology of TCM-derived bioactive compounds in Alzheimer’s disease: molecular targets, standardization, and translational insights · 2026 · Related
  17. Pharmacological actions of curcumin in liver diseases or damage · Yadira Rivera‐Espinoza · 2009 · 192 citations · Cited by this paper
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  19. Curcumin regulates endogenous and exogenous metabolism via Nrf2-FXR-LXR pathway in NAFLD mice · Caixia Yan · 2018 · 169 citations · Cited by this paper
  20. From Qi to synapse: A systems-based review of Traditional Chinese Medicine in the treatment of major depressive disorder · 2026 · Related
  21. Curcumin ameliorates liver damage and progression of NASH in NASH-HCC mouse model possibly by modulating HMGB1-NF-κB translocation · Rejina Afrin · 2017 · 123 citations · Cited by this paper
  22. A polymeric nanoparticle formulation of curcumin (NanoCurc™) ameliorates CCl4-induced hepatic injury and fibrosis through reduction of pro-inflammatory cytokines and stellate cell activation · Savita Bisht · 2011 · 118 citations · Cited by this paper
  23. Curcumin limits the fibrogenic evolution of experimental steatohepatitis · Francesco Vizzutti · 2009 · 105 citations · Cited by this paper
  24. Curcumin administration suppresses collagen synthesis in the hearts of rats with experimental diabetes · Shuang Guo · 2017 · 99 citations · Cited by this paper
  25. Μetabolic dysfunction-associated steatotic liver disease: a condition of heterogeneous metabolic risk factors, mechanisms and comorbidities requiring holistic treatment · Christopher D. Byrne · 2025 · 86 citations · Cited by this paper
  26. Traditional Chinese medicine for prevention and treatment of hepatocarcinoma: From bench to bedside · Bing Hu · 2015 · 81 citations · Cited by this paper
  27. Curcumin Ameliorates Streptozotocin-Induced Heart Injury in Rats · Osama M. Abo‐Salem · 2014 · 44 citations · Cited by this paper
  28. Dietary Supplemented Curcumin Improves Meat Quality and Antioxidant Status of Intrauterine Growth Retardation Growing Pigs via Nrf2 Signal Pathway · Ligen Zhang · 2020 · 44 citations · Cited by this paper
  29. Predicting the future burden of NAFLD and NASH · Suzanne E. Mahady · 2018 · 43 citations · Cited by this paper
  30. Hepatoprotective effect of curcumin against bisphenol A-induced hepatic steatosis via modulating gut microbiota dysbiosis and related gut-liver axis activation in CD-1 mice · Ting Hong · 2022 · 43 citations · Cited by this paper
  31. Molecular Mechanisms of Curcumin in the Pathogenesis of Metabolic Dysfunction Associated Steatotic Liver Disease · Marta Guariglia · 2023 · 38 citations · Cited by this paper
  32. Nanocurcumin and curcumin prevent N, N'-methylenebisacrylamide-induced liver damage and promotion of hepatic cancer cell growth · Mona Mohamed Atia · 2022 · 35 citations · Cited by this paper
  33. Potential Roles and Mechanisms of Curcumin and its Derivatives in the Regulation of Ferroptosis · Yuan Zhang · 2024 · 33 citations · Cited by this paper
  34. Effect of curcumin on the non-alcoholic steatohepatitis via inhibiting the M1 polarization of macrophages · Cong Tong · 2021 · 30 citations · Cited by this paper
  35. Curcumin protects against bisphenol A‐induced hepatic steatosis by inhibiting cholesterol absorption and synthesis in CD ‐1 mice · Ting Hong · 2023 · 30 citations · Cited by this paper
  36. Advances and Perspectives in Curcumin Regulation of Systemic Metabolism: A Focus on Multi-Organ Mechanisms · Dingya Sun · 2026 · 30 citations · Cited by this paper
  37. Curcumin Compensates GLP‐1 Deficiency via the Microbiota‐Bile Acids Axis and Modulation in Functional Crosstalk between TGR5 and FXR in ob/ob Mice · Fengyuan Tian · 2023 · 29 citations · Cited by this paper
  38. Curcumin activation of nuclear factor E2-related factor 2 gene (Nrf2): Prophylactic and therapeutic effect in nonalcoholic steatohepatitis (NASH) · Nahla Mohammed Abd El-Hameed · 2021 · 28 citations · Cited by this paper
  39. Effectiveness of curcumin nanoparticles in rat liver fibrosis caused by thioacetamide · Aliaa M. Radwan · 2023 · 28 citations · Cited by this paper

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