Research map: DOTAM-TCB: A Universal Small Molecule-Guided Hapten- and T Cell-Bispecific Antibodies for Cancer Immunotherapy

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  1. Lutetium-177–PSMA-617 for Metastatic Castration-Resistant Prostate Cancer · Oliver A. Sartor · 2021 · 2844 citations · Cited by this paper
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  15. Emerging Opportunities and Challenges in Cancer Immunotherapy · Theresa L. Whiteside · 2016 · 318 citations · Cited by this paper
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  17. Biologics vs. small molecules: Drug costs and patient access · Favour Danladi Makurvet · 2020 · 268 citations · Cited by this paper
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  19. CD20-TCB with Obinutuzumab Pretreatment as Next-Generation Treatment of Hematologic Malignancies · Marina Bacac · 2018 · 254 citations · Cited by this paper
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  21. Folate targeting of haptens to cancer cell surfaces mediates immunotherapy of syngeneic murine tumors · Philip S. Low · 2002 · 186 citations · Cited by this paper
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  23. Clinical Translation and First In-Human Use of [44Sc]Sc-PSMA-617 for PET Imaging of Metastasized Castrate-Resistant Prostate Cancer · Elisabeth Eppard · 2017 · 146 citations · Cited by this paper
  24. Use of a Single CAR T Cell and Several Bispecific Adapters Facilitates Eradication of Multiple Antigenically Different Solid Tumors · Yong Gu Lee · 2018 · 138 citations · Cited by this paper
  25. Substantial Energetic Improvement with Minimal Structural Perturbation in a High Affinity Mutant Antibody · Katarina Senn Midelfort · 2004 · 135 citations · Cited by this paper
  26. Chemical Control over Immune Recognition: A Class of Antibody-Recruiting Small Molecules That Target Prostate Cancer · Ryan P. Murelli · 2009 · 134 citations · Cited by this paper
  27. Efficient tumor killing and minimal cytokine release with novel T-cell agonist bispecific antibodies · Nathan D. Trinklein · 2019 · 111 citations · Cited by this paper
  28. Carbonic anhydrase XIV: Luminal expression suggests key role in renal acidification · Kari Kaunisto · 2002 · 97 citations · Cited by this paper
  29. Current modalities in cancer immunotherapy: Immunomodulatory antibodies, CARs and vaccines · Jason J. Lohmueller · 2017 · 93 citations · Cited by this paper
  30. Ten years in the making: application of CrossMab technology for the development of therapeutic bispecific antibodies and antibody fusion proteins · Marlena Surowka · 2021 · 93 citations · Cited by this paper
  31. Isolation and affinity maturation of hapten-specific antibodies · Claudia Sheedy · 2007 · 85 citations · Cited by this paper
  32. Engineering an antibody with picomolar affinity to DOTA chelates of multiple radionuclides for pretargeted radioimmunotherapy and imaging · Kelly Davis Orcutt · 2010 · 73 citations · Cited by this paper
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  34. Novel strategies for the mitigation of cytokine release syndrome induced by T cell engaging therapies with a focus on the use of kinase inhibitors · Gabrielle Leclercq-Cohen · 2022 · 69 citations · Cited by this paper
  35. Expression of Carbonic Anhydrase IX in Mouse Tissues · Mika Hilvo · 2004 · 61 citations · Cited by this paper
  36. Physiologically based pharmacokinetic models of small molecules and therapeutic antibodies: a mini‐review on fundamental concepts and applications · Gregory Z. Ferl · 2015 · 54 citations · Cited by this paper
  37. The structural comparison between membrane‐associated human carbonic anhydrases provides insights into drug design of selective inhibitors · Vincenzo Alterio · 2013 · 52 citations · Cited by this paper
  38. Carbonic anhydrase inhibitors. Inhibition of isoforms I, II, IV, VA, VII, IX, and XIV with sulfonamides incorporating fructopyranose–thioureido tails · Jean‐Yves Winum · 2007 · 52 citations · Cited by this paper
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